Disease on EC 1.13.12.7 - firefly luciferase
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Acidosis
Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism.
Adenocarcinoma
Biodegradable CpG DNA hydrogels for sustained delivery of doxorubicin and immunostimulatory signals in tumor-bearing mice.
Adenocarcinoma
Establishment of a cellular assay system for G protein-linked receptors: coupling of human NK2 and 5-HT2 receptors to phospholipase C activates a luciferase reporter gene.
Adenocarcinoma
Simultaneous delivery of doxorubicin and immunostimulatory CpG motif to tumors using a plasmid DNA/doxorubicin complex in mice.
Adenocarcinoma of Lung
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Adenoviridae Infections
Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene.
Alzheimer Disease
A new bioluminescence-based tool for modulating target proteins in live cells.
Asthma
Ability of polymorphonuclear leukocytes to generate active oxygen species in children with bronchial asthma. Use of chemiluminescence probes with a Cypridina luciferin analog and luminol.
Bacteriuria
Analysis of the disagreement between automated bioluminescence-based and culture methods for detecting significant bacteriuria, with proposals for standardizing evaluations of bacteriuria detection methods.
Bacteriuria
Evaluation of an adenosine 5'-triphosphate assay as a screening method to detect significant bacteriuria.
Bacteriuria
Screening of bacteria in urine using luciferin-luciferase assay of microbial ATP: a comparative study.
Brain Injuries
In vivo bioluminescence imaging of neurogenesis - the role of the blood brain barrier in an experimental model of Parkinson's disease.
Brain Neoplasms
A novel pre-clinical in vivo mouse model for malignant brain tumor growth and invasion.
Brain Neoplasms
A novel rat model for glioblastoma multiforme using a bioluminescent F98 cell line.
Brain Neoplasms
Angiogenesis-targeting microbubbles combined with ultrasound-mediated gene therapy in brain tumors.
Brain Neoplasms
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Brain Neoplasms
Evaluation of a bispecific biological drug designed to simultaneously target glioblastoma and its neovasculature in the brain.
Brain Neoplasms
Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging.
Brain Neoplasms
Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery.
Brain Neoplasms
Pulsed-wave low-dose ultrasound hyperthermia selectively enhances nanodrug delivery and improves antitumor efficacy for brain metastasis of breast cancer.
Brain Neoplasms
Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging.
Breast Neoplasms
A multimodality imaging model to track viable breast cancer cells from single arrest to metastasis in the mouse brain.
Breast Neoplasms
A Novel Cationic Microbubble Coated with Stearic Acid-Modified Polyethylenimine to Enhance DNA Loading and Gene Delivery by Ultrasound.
Breast Neoplasms
A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy.
Breast Neoplasms
Anti?inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF??B pathway.
Breast Neoplasms
Assessment of therapeutic efficacy of liposomal nanoparticles mediated gene delivery by molecular imaging for cancer therapy.
Breast Neoplasms
C19 steroids estrogenic activity in human breast cancer cell lines: importance of dehydroepiandrosterone sulfate at physiological plasma concentration.
Breast Neoplasms
Conversion of dehydroepiandrosterone sulfate at physiological plasma concentration into estrogens in MCF-7 cells.
Breast Neoplasms
Dehydroepiandrosterone sulfate estrogenic action at its physiological plasma concentration in human breast cancer cell lines.
Breast Neoplasms
Determination of chemotherapeutic activity in vivo by luminescent imaging of luciferase-transfected human tumors.
Breast Neoplasms
Development of lipopolyplexes for gene delivery: A comparison of the effects of differing modes of targeting peptide display on the structure and transfection activities of lipopolyplexes.
Breast Neoplasms
Egr-1 is activated by 17beta-estradiol in MCF-7 cells by mitogen-activated protein kinase-dependent phosphorylation of ELK-1.
Breast Neoplasms
Enhanced Anti-Tumor Efficacy through a Combination of Integrin ?v?6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition.
Breast Neoplasms
Estrogenic/antiestrogenic activity of selected selective serotonin reuptake inhibitors.
Breast Neoplasms
In vivo long-term investigation of tumor bearing mKate2 by an in-house fluorescence molecular imaging system.
Breast Neoplasms
In vivo monitoring of CD44+ cancer stem-like cells by ?-irradiation in breast cancer.
Breast Neoplasms
In Vivo Photoactivation Without "Light": Use of Cherenkov Radiation to Overcome the Penetration Limit of Light.
Breast Neoplasms
Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis.
Breast Neoplasms
Molecular imaging for assessment of mesenchymal stem cells mediated breast cancer therapy.
Breast Neoplasms
Molecular Imaging of Tumor Angiogenesis and Therapeutic Effects with Dual Bioluminescence.
Breast Neoplasms
Multimodal fluorescence- and bioluminescence imaging reveals transfection potential of intratracheally administered polyplexes for breast cancer lung metastases.
Breast Neoplasms
Phosphorylatable short peptide conjugated low molecular weight chitosan for efficient siRNA delivery and target gene silencing.
Breast Neoplasms
Prolonged treatment of breast cancer cells with antiestrogens increases the activating protein-1-mediated response: involvement of the estrogen receptor.
Breast Neoplasms
Pulsed-wave low-dose ultrasound hyperthermia selectively enhances nanodrug delivery and improves antitumor efficacy for brain metastasis of breast cancer.
Breast Neoplasms
Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation.
Breast Neoplasms
Repair of mitomycin C cross-linked DNA in mammalian cells measured by a host cell reactivation assay.
Breast Neoplasms
Short-time focused ultrasound hyperthermia enhances liposomal doxorubicin delivery and antitumor efficacy for brain metastasis of breast cancer.
Breast Neoplasms
Targeting trastuzumab-resistant breast cancer cells with a lentivirus engineered to bind antibodies that recognize HER-2.
Breast Neoplasms
The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs.
Breast Neoplasms
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
Breast Neoplasms
Tubulin-Destabilizing Agent BPR0L075 Induces Vascular-Disruption in Human Breast Cancer Mammary Fat Pad Xenografts.
Breast Neoplasms
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Bronchitis
Towards Construction of Viral Vectors Based on Avian Coronavirus Infectious Bronchitis Virus for Gene Delivery and Vaccine Development.
Burkitt Lymphoma
Longitudinal Monitoring of Antibody Responses against Tumor Cells Using Magneto-nanosensors with a Nanoliter of Blood.
Carcinogenesis
The human splice variant ?16HER2 induces rapid tumor onset in a reporter transgenic mouse.
Carcinoma
A nonviral vector with transfection activity comparable with adenoviral transduction.
Carcinoma
An immunocompetent murine model of metastatic mammary cancer accessible to bioluminescence imaging.
Carcinoma
Detailed assessment of gene activation levels by multiple hypoxia-responsive elements under various hypoxic conditions.
Carcinoma
Effect of Sugar 2',4'-Modifications on Gene Silencing Activity of siRNA Duplexes.
Carcinoma
Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging.
Carcinoma
Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro.
Carcinoma
Fractionated Radiation Severely Reduces the Number of CD8+ T Cells and Mature Antigen Presenting Cells Within Lung Tumors.
Carcinoma
Human bone marrow mesenchymal stem cells functionalized by hybrid baculovirus-adeno-associated viral vectors for targeting hypopharyngeal carcinoma.
Carcinoma
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.
Carcinoma
Interference of contaminated sediment extracts and environmental pollutants with retinoid signaling.
Carcinoma
Investigation on the transcription factors of porcine 3?-hydroxysteroid dehydrogenase and 17?-hydroxysteroid dehydrogenase genes.
Carcinoma
Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts.
Carcinoma
NS-398, a selective cyclooxygenase-2 inhibitor, reduces experimental bladder carcinoma outgrowth by inhibiting tumor cell proliferation.
Carcinoma
Potent preclinical impact of metronomic low-dose oral topotecan combined with the antiangiogenic drug pazopanib for the treatment of ovarian cancer.
Carcinoma
Synergistic effect of interstitial laser coagulation and doxorubicin in a murine tumor recurrence model of solitary colorectal liver metastasis.
Carcinoma
Use of the ODD-Luciferase Transgene for the Non-Invasive Imaging of Spontaneous Tumors in Mice.
Carcinoma
Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3.
Carcinoma, Embryonal
Vasopressin gene expression is stimulated by cyclic AMP in homologous and heterologous expression systems.
Carcinoma, Hepatocellular
A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.
Carcinoma, Hepatocellular
Application of molecular imaging technology in evaluating the inhibiting effect of apigenin in vivo on subcutaneous hepatocellular carcinoma.
Carcinoma, Hepatocellular
Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds.
Carcinoma, Hepatocellular
Cloning and characterization of the promoter region of a gene encoding a 67-kDa glycoprotein.
Carcinoma, Hepatocellular
Cloning the genomic sequence and identification of promoter regions of bovine pyruvate carboxylase.
Carcinoma, Hepatocellular
Comprehensive evaluation of the anti-angiogenic and anti-neoplastic effects of Endostar on liver cancer through optical molecular imaging.
Carcinoma, Hepatocellular
Correlation between luminescence intensity and cytotoxicity in cell-based cytotoxicity assay using luciferase.
Carcinoma, Hepatocellular
Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter.
Carcinoma, Hepatocellular
Dual-modality monitoring of tumor response to cyclophosphamide therapy in mice with bioluminescence imaging and small-animal positron emission tomography.
Carcinoma, Hepatocellular
Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta.
Carcinoma, Hepatocellular
Impaired ability of neutrophils to produce oxygen-derived free radicals in patients with chronic liver disease and hepatocellular carcinoma.
Carcinoma, Hepatocellular
In Vitro Design and Characterization of the Nonviral Gene Delivery Vector Iopamidol, Protamine, Ethiodized Oil Reagent.
Carcinoma, Hepatocellular
Inhibition of hepatitis C virus gene expression by adenoviral vectors encoding antisense RNA in vitro and in vivo.
Carcinoma, Hepatocellular
Inhibition of internal ribosomal entry site-directed translation of HCV by recombinant IFN-alpha correlates with a reduced La protein.
Carcinoma, Hepatocellular
Isolation and characterization of the human gp130 promoter. Regulation by STATS.
Carcinoma, Hepatocellular
Molecular cloning and sequence analysis of the rat liver carnitine octanoyltransferase cDNA, its natural gene and the gene promoter.
Carcinoma, Hepatocellular
Nuclear uptake of the Ah (dioxin) receptor in response to omeprazole: transcriptional activation of the human CYP1A1 gene.
Carcinoma, Hepatocellular
Propionate induces the bovine cytosolic phosphoenolpyruvate carboxykinase promoter activity.
Carcinoma, Hepatocellular
Regulation of human apolipoprotein A-I expression in Caco-2 and HepG2 cells by all-trans and 9-cis retinoic acids.
Carcinoma, Hepatocellular
Relative potencies of PAHs and PCBs based on the response of human cells.
Carcinoma, Hepatocellular
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.
Carcinoma, Hepatocellular
Trout CYP1A3 Gene: Recognition of Fish DNA Motifs by Mouse Regulatory Proteins.
Carcinoma, Hepatocellular
Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1.
Carcinoma, Lewis Lung
Fractionated Radiation Severely Reduces the Number of CD8+ T Cells and Mature Antigen Presenting Cells Within Lung Tumors.
Carcinoma, Non-Small-Cell Lung
Identification of miR-200a-5p targeting the peptide transporter TAP1 and its association with the clinical outcome of melanoma patients.
Carcinoma, Renal Cell
Arabinonucleic acids: 2'-stereoisomeric modulators of siRNA activity.
Carcinoma, Renal Cell
Effect of Sugar 2',4'-Modifications on Gene Silencing Activity of siRNA Duplexes.
Carcinoma, Squamous Cell
Longitudinal bioluminescence imaging of the dynamics of Doxorubicin induced apoptosis.
Cardiomegaly
Identification and visualization of stimulus-specific transcriptional activity in cardiac hypertrophy in mice.
Cardiovascular Diseases
A Synthetic Luciferin Improves In Vivo Bioluminescence Imaging of Gene Expression in Cardiovascular Brain Regions.
Central Nervous System Infections
Persistent infection of a gammaherpesvirus in the central nervous system.
Choriocarcinoma
Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.
Choriocarcinoma
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
Classical Swine Fever
Generation of a recombinant classical swine fever virus stably expressing the firefly luciferase gene for quantitative antiviral assay.
Coinfection
Dual Reporter Comparative Indexing of rAAV Pseudotyped Vectors in Chimpanzee Airway.
Colonic Neoplasms
Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model.
Colonic Neoplasms
Visualization of the Biological Behavior of Tumor-Associated Macrophages in Living Mice with Colon Cancer Using Multimodal Optical Reporter Gene Imaging.
Colorectal Neoplasms
A cell-based screen for inhibitors of protein folding and degradation.
Colorectal Neoplasms
Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors.
Colorectal Neoplasms
Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model.
Dehydration
Quantitative imaging of gene expression in individual bacterial cells by chemiluminescence.
Dengue
Towards Construction of Viral Vectors Based on Avian Coronavirus Infectious Bronchitis Virus for Gene Delivery and Vaccine Development.
Diabetes Mellitus
Improvement of an impaired chemiluminescence response to formyl-methionyl-leucyl-phenylalanine in neutrophils from patients with non insulin dependent diabetes mellitus by recombinant human granulocyte-colony stimulating factor.
Diabetes Mellitus, Type 1
Simultaneous in vivo monitoring of regulatory and effector T lymphocytes using secreted Gaussia luciferase, Firefly luciferase, and secreted alkaline phosphatase.
Diphtheria
Ribozyme-mediated selective induction of new gene activity in hepatitis C virus internal ribosome entry site-expressing cells by targeted trans-splicing.
Distemper
Host range and receptor utilization of canine distemper virus analyzed by recombinant viruses: Involvement of heparin-like molecule in CDV infection.
Encephalitis, Viral
Visualizing production of interferon-? by astrocytes and microglia in the brain of La Crosse virus-infected mice.
Encephalomyelitis
Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain.
Feline Infectious Peritonitis
Coronaviruses as vectors: stability of foreign gene expression.
Fetal Death
Enhanced in vivo gene transfer into the placenta using RGD fiber-mutant adenovirus vector.
Fibrosarcoma
Cell cycle arrest drastically extends the duration of gene silencing after transient expression of short hairpin RNA.
Fibrosarcoma
Human U6 promoter drives stronger shRNA activity than its schistosome orthologue in Schistosoma mansoni and human fibrosarcoma cells.
Fibrosarcoma
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Fibrosarcoma
Resistance to heat radiosensitization and protein damage in thermotolerant and thermoresistant cells.
Glioblastoma
A novel bispecific ligand-directed toxin designed to simultaneously target EGFR on human glioblastoma cells and uPAR on tumor neovasculature.
Glioblastoma
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Glioblastoma
Firefly Luciferase Inhibitor-Conjugated Peptide Quenches Bioluminescence: A Versatile Tool for Real Time Monitoring Cellular Uptake of Biomolecules.
Glioblastoma
Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response.
Glioblastoma
In Vivo Follow-Up of Gene Inhibition in Solid Tumors Using Peptide-Based Nanoparticles for siRNA Delivery.
Glioblastoma
Multimodal molecular imaging system for pathway-specific reporter gene expression.
Glioblastoma
Therapeutic Effect of IL-4 Receptor-Targeting Pro-Apoptotic Peptide (AP1-ELP-KLAK) in Glioblastoma Tumor Model.
Glioma
A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma.
Glioma
Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging.
Glioma
Development and Characterisation of a Novel NF-?B Reporter Cell Line for Investigation of Neuroinflammation.
Glioma
Evaluation of a bispecific biological drug designed to simultaneously target glioblastoma and its neovasculature in the brain.
Glioma
Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression.
Glioma
In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model.
Glioma
Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery.
Glioma
Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect.
Glioma
Synergistic inhibition of glioma cell proliferation by Withaferin A and tumor treating fields.
Glioma
Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells.
Glioma
Using [¹?F]FBAU for imaging brain tumor progression in an F98/tk-luc glioma-bearing rat model.
Gliosarcoma
Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging.
Gliosarcoma
The influence of hypoxia on bioluminescence in luciferase-transfected gliosarcoma tumor cells in vitro.
Hepatitis
Evaluating post-transcriptional regulatory elements for enhancing transient gene expression levels in CHO K1 and HEK293 cells.
Hepatitis
Fluorogenic RNA nanoparticles for monitoring RNA folding and degradation in real time in living cells.
Hepatitis
Impaired ability of neutrophils to produce oxygen-derived free radicals in patients with chronic liver disease and hepatocellular carcinoma.
Hepatitis
Influence of murine hepatitis induced by D-(+)-galactosamine hydrochloride and lipopolysaccharide on gene expression of polyethylenimine/plasmid DNA polyplex.
Hepatitis A
Replication of subgenomic hepatitis A virus RNAs expressing firefly luciferase is enhanced by mutations associated with adaptation of virus to growth in cultured cells.
Hepatitis B
Development of ultra-high sensitivity bioluminescent enzyme immunoassay for hepatitis B virus surface antigen using firefly luciferase.
Hepatitis B
Practical application of bioluminescence enzyme immunoassay using enhancer for firefly luciferin-luciferase bioluminescence.
Hepatitis B
Use of SV40-based vectors to transduce foreign genes to normal human peripheral blood mononuclear cells.
Hepatitis C
Activation of interferon-stimulated response element in huh-7 cells replicating hepatitis C virus subgenomic RNA.
Hepatitis C
Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon.
Hepatitis C
Two flavonoids extracts from Glycyrrhizae radix inhibit in vitro hepatitis C virus replication.
Hepatitis, Chronic
Impaired ability of neutrophils to produce oxygen-derived free radicals in patients with chronic liver disease and hepatocellular carcinoma.
Hepatoblastoma
Bioluminescence Measurement of Time-Dependent Dynamic Changes of CYP-Mediated Cytotoxicity in CYP-Expressing Luminescent HepG2 Cells.
Hepatoblastoma
Synergistic enhansons located within an acute phase responsive enhancer modulate glucocorticoid induction of angiotensinogen gene transcription.
Herpes Simplex
A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma.
Herpes Simplex
A Tri-fusion Reporter Mouse Reveals Tissue-Specific FGF1B Promoter Activity in vivo.
Herpes Simplex
An A/G-rich motif in the rat fibroblast growth factor-2 gene confers enhancer activity on a heterologous promoter in neonatal rat cardiac myocytes.
Herpes Simplex
An optimized triple modality reporter for quantitative in vivo tumor imaging and therapy evaluation.
Herpes Simplex
Angiogenesis-targeting microbubbles combined with ultrasound-mediated gene therapy in brain tumors.
Herpes Simplex
Coexpression of the partial androgen receptor enhances the efficacy of prostate-specific antigen promoter-driven suicide gene therapy for prostate cancer cells at low testosterone concentrations.
Herpes Simplex
Controlling and monitoring stem cell safety in vivo in an experimental rodent model.
Herpes Simplex
CRISPR/Cas9-edited triple-fusion reporter gene imaging of dynamics and function of transplanted human urinary-induced pluripotent stem cell-derived cardiomyocytes.
Herpes Simplex
Effect of the rabbit alphas1-casein gene distal enhancer on the expression of a reporter gene in vitro and in vivo.
Herpes Simplex
Effects of Endogenous Proteins and microRNA Target Sequence in a Positive Feedback System.
Herpes Simplex
Efficient targeting and tumor retardation effect of pancreatic adenocarcinoma up-regulated factor (PAUF)-specific RNA replacement in pancreatic cancer mouse model.
Herpes Simplex
Fetal gene transfer using lentiviral vectors: in vivo detection of gene expression by microPET and optical imaging in fetal and infant monkeys.
Herpes Simplex
Genetic incorporation of a herpes simplex virus type 1 thymidine kinase and firefly luciferase fusion into the adenovirus protein IX for functional display on the virion.
Herpes Simplex
Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells with Zinc Finger Nuclease for Cellular Imaging.
Herpes Simplex
Human embryonic stem cell-derived cardiomyocyte therapy in mouse permanent ischemia and ischemia-reperfusion models.
Herpes Simplex
Imaging of Sleeping Beauty-Modified CD19-Specific T Cells Expressing HSV1-Thymidine Kinase by Positron Emission Tomography.
Herpes Simplex
Improvement of the monitoring and biosafety of encapsulated cells using the SFGNESTGL triple reporter system.
Herpes Simplex
Long term non-invasive imaging of embryonic stem cells using reporter genes.
Herpes Simplex
Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation.
Herpes Simplex
Molecular Imaging of Tumor Angiogenesis and Therapeutic Effects with Dual Bioluminescence.
Herpes Simplex
Multimodality molecular imaging to monitor transplanted stem cells for the treatment of ischemic heart disease.
Herpes Simplex
Noninvasive imaging of lentiviral-mediated reporter gene expression in living mice.
Herpes Simplex
Rational design of a triple reporter gene for multimodality molecular imaging.
Herpes Simplex
Second-generation triple reporter for bioluminescence, micro-positron emission tomography, and fluorescence imaging.
Herpes Simplex
Simultaneous imaging of temporal changes of NF-?B activity and viable tumor cells in Huh7/NF-?B-tk-luc2/rfp tumor-bearing mice.
Herpes Simplex
Spying on cancer: molecular imaging in vivo with genetically encoded reporters.
Herpes Simplex
Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor.
Herpes Simplex
Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice.
Herpes Simplex
Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters.
Herpes Simplex
Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases.
Herpes Simplex
Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice.
Herpes Simplex
Using [¹?F]FBAU for imaging brain tumor progression in an F98/tk-luc glioma-bearing rat model.
Herpesviridae Infections
Video imaging of firefly luciferase activity to identify and monitor herpesvirus infection in cell culture.
HIV Infections
Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses.
HIV Infections
Use of new T-cell-based cell lines expressing two luciferase reporters for accurately evaluating susceptibility to anti-human immunodeficiency virus type 1 drugs.
Huntington Disease
Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells.
Hypersensitivity
Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model.
Hyperthyroidism
Evaluation of highly sensitive thyrotropin assay for detecting thyroid diseases in neonatal screening: preliminary studies.
Hypothyroidism
Evaluation of highly sensitive thyrotropin assay for detecting thyroid diseases in neonatal screening: preliminary studies.
Infections
4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency.
Infections
A quantitative assay for measuring of bovine immunodeficiency virus using a luciferase-based indicator cell line.
Infections
Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain.
Infections
Adoptive immunotherapy mediated by ex vivo expanded natural killer T cells against CD1d-expressing lymphoid neoplasms.
Infections
An LASV GPC pseudotyped virus based reporter system enables evaluation of vaccines in mice under non-BSL-4 conditions.
Infections
Biodistribution and residence time of adenovector serotype 5 in normal and immunodeficient mice and rats detected with bioluminescent imaging.
Infections
Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread.
Infections
Detection of Bioluminescent Borrelia burgdorferi from In Vitro Cultivation and During Murine Infection.
Infections
Effect of a Single Nucleotide Polymorphism in the LAMA1 Promoter Region on Transcriptional Activity: Implication for Pathological Myopia.
Infections
ENTRY SITES OF VENEZUELAN AND WESTERN EQUINE ENCEPHALITIS VIRUSES IN THE MOUSE CENTRAL NERVOUS SYSTEM FOLLOWING PERIPHERAL INFECTION.
Infections
Expression of human amyloid precursor proteins in cultured neuronal cells through the use of HSV-1 defective vectors.
Infections
Generation of stable L. major(+EGFP-LUC) and simultaneous comparison between EGFP and luciferase sensitivity.
Infections
Human Adipose Tissue Stem Cells Promote the Growth of Acute Lymphoblastic Leukemia Cells in NOD/SCID Mice.
Infections
Imaging gene expression in live transgenic mice after providing luciferin in drinking water.
Infections
Improvement of an impaired chemiluminescence response to formyl-methionyl-leucyl-phenylalanine in neutrophils from patients with non insulin dependent diabetes mellitus by recombinant human granulocyte-colony stimulating factor.
Infections
In vivo bioluminescence imaging for prolonged survival of transplanted human neural stem cells using 3D biocompatible scaffold in corticectomized rat model.
Infections
Luciferase real-time bioluminescence imaging for the study of viral pathogenesis.
Infections
Measurement of Mouse Cytomegalovirus-Induced Interferon-? with Immortalized Luciferase Reporter Cells.
Infections
Miltefosine enhances infectivity of a miltefosine-resistant Leishmania infantum strain by attenuating its innate immune recognition.
Infections
Monitoring recombinant baculovirus replication in Spodoptera litura (Lepidoptera: Noctuidae) larvae by using firefly luciferase gene as a reporter.
Infections
Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice.
Infections
Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1.
Infections
Pathology and immunogenicity in the cotton rat (Sigmodon hispidus) model after infection with a bovine adenovirus type 3 recombinant virus expressing the firefly luciferase gene.
Infections
Red-Shifted Firefly Luciferase Optimized for Candida albicans In vivo Bioluminescence Imaging.
Infections
Simultaneous synthesis of enzymatically active luciferase and biologically active beta subunit of human chorionic gonadotropin in caterpillars infected with a recombinant baculovirus.
Infections
Successful biolistic transformation of mouse pancreatic islets while preserving cellular function.
Infections
Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells.
Infections
Targeting of suicide gene delivery in pancreatic cancer cells via FGF receptors.
Infections
Titration of cell-associated varicella-zoster virus with the MV9G reporter cell line for antiviral studies.
Infections
Transcriptional transactivation of parvovirus B19 promoters in nonpermissive human cells by adenovirus type 2.
Infections
Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice.
Infections
Tropism of human adenovirus type 5-based vectors in swine and their ability to protect against transmissible gastroenteritis coronavirus.
Influenza, Human
In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses.
Influenza, Human
The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes.
Influenza, Human
Virus-inducible reporter genes as a tool for detecting and quantifying influenza A virus replication.
Kidney Neoplasms
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Leukemia
Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission.
Leukemia
Factors affecting long-term stability of Moloney murine leukemia virus-based vectors.
Leukemia
Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles.
Leukemia
Neutralization Assay with SARS-CoV-1 and SARS-CoV-2 Spike Pseudotyped Murine Leukemia Virions.
Leukemia
Neutralization assay with SARS-CoV-1 and SARS-CoV-2 spike pseudotyped murine leukemia virions.
Leukemia
Topoisomerase II alpha promoter trans-activation early in monocytic differentiation of HL-60 human leukemia cells.
Leukemia
Use of Humanized RS-ATL8 Reporter System for Detection of Allergen-Specific IgE Sensitization in Human Food Allergy.
Leukemia, Erythroblastic, Acute
A new system that analyzes erythropoietin-mediated early signal transduction: transfection of the c-fos enhancer.promoter-luciferase gene into a murine erythroid cell line.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Comparison of cell-labeling methods with ¹²?I-FIAU and ??Cu-PTSM for cell tracking using chronic myelogenous leukemia cells expressing HSV1-tk and firefly luciferase.
Liver Diseases
Impaired ability of neutrophils to produce oxygen-derived free radicals in patients with chronic liver disease and hepatocellular carcinoma.
Lung Diseases
Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung.
Lung Neoplasms
Bioluminescence imaging correlates with tumor progression in an orthotopic mouse model of lung cancer.
Lung Neoplasms
Gene silencing activity of siRNA polyplexes based on biodegradable polymers.
Lung Neoplasms
Gene Silencing Activity of siRNA Polyplexes Based on Thiolated N,N,N-Trimethylated Chitosan.
Lung Neoplasms
Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library.
Lung Neoplasms
Overexpression of CXCR7 accelerates tumor growth and metastasis of lung cancer cells.
Lung Neoplasms
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Lymphoma
Human umbilical cord mesenchymal stem cells as vehicles of CD20-specific TRAIL fusion protein delivery: a double-target therapy against non-Hodgkin's lymphoma.
Lymphoma
Longitudinal Monitoring of Antibody Responses against Tumor Cells Using Magneto-nanosensors with a Nanoliter of Blood.
Lymphoma
Non-invasive bioluminescence imaging to monitor the immunological control of a plasmablastic lymphoma-like B cell neoplasia after hematopoietic cell transplantation.
Lymphoma, B-Cell
Non-invasive bioluminescence imaging to monitor the immunological control of a plasmablastic lymphoma-like B cell neoplasia after hematopoietic cell transplantation.
Malaria
An ultrasensitive NanoLuc-based luminescence system for monitoring Plasmodium berghei throughout its life cycle.
Melanoma
Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression.
Melanoma
Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice.
Melanoma
Efficient gene transfer into Xiphophorus muscle and melanoma by injection of supercoiled plasmid DNA.
Melanoma
Identification of a cis-acting element that enhances the pigment cell-specific expression of the human tyrosinase gene.
Melanoma
Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene.
Melanoma
Imaging of Firefly Luciferase Activity under Antiangiogenic Therapy in a Heat Shock Protein 70-Transfected Melanoma Tumor Model.
Melanoma
Imaging of Red-Shifted Light From Bioluminescent Tumors Using Fluorescence by Unbound Excitation From Luminescence.
Melanoma
In vivo electroporation-mediated transfer of interleukin-12 and interleukin-18 genes induces significant antitumor effects against melanoma in mice.
Melanoma
Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells.
Melanoma
Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice.
Melanoma
Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis.
Melanoma
Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene.
Melanoma
Pivotal role of oxidative stress in tumor metastasis under diabetic conditions in mice.
Melanoma
Quantitative and temporal analysis of gene silencing in tumor cells induced by small interfering RNA or short hairpin RNA expressed from plasmid vectors.
Melanoma
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Metabolic Diseases
In vivo monitoring of pancreatic beta-cells in a transgenic mouse model.
Multiple Myeloma
A bioluminescence imaging based in vivo model for preclinical testing of novel cellular immunotherapy strategies to improve the graft-versus-myeloma effect.
Multiple Sclerosis
[Construction and identification of luciferase reporter gene containing mouse T-bet promoter].
Muscular Dystrophies
Induced Pluripotent Stem Cells derived Muscle Progenitors Effectively Mitigate Muscular Dystrophy through Restoring the Dystrophin Distribution.
Mycoses
Visualizing fungal infections in living mice using bioluminescent pathogenic Candida albicans strains transformed with the firefly luciferase gene.
Myocardial Infarction
IGF-1C domain-modified hydrogel enhanced the efficacy of stem cells in the treatment of AMI.
Myocardial Infarction
Multimodality molecular imaging to monitor transplanted stem cells for the treatment of ischemic heart disease.
Myocardial Infarction
The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia.
Nasopharyngeal Carcinoma
Differential expression in human cells from the p6 promoter of human parvovirus B19 following plasmid transfection and recombinant adeno-associated virus 2 (AAV) infection: human megakaryocytic leukaemia cells are non-permissive for AAV infection.
Neoplasm Metastasis
An orthotopic, postsurgical model of luciferase transfected murine osteosarcoma with spontaneous metastasis.
Neoplasm Metastasis
Characterization of thyroid cancer cell lines in murine orthotopic and intracardiac metastasis models.
Neoplasm Metastasis
Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases.
Neoplasm Metastasis
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Neoplasm Metastasis
Development of bone-targeted catalase derivatives for inhibition of bone metastasis of tumor cells in mice.
Neoplasm Metastasis
Differential microRNA expression profiles in HCT116 colorectal cancer cell lines located in the lung and colon.
Neoplasm Metastasis
Establishment of animal model for the analysis of cancer cell metastasis during radiotherapy.
Neoplasm Metastasis
Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.
Neoplasm Metastasis
Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis.
Neoplasm Metastasis
High Sensitivity In Vivo Imaging of Cancer Metastasis Using a Near-Infrared Luciferin Analogue seMpai.
Neoplasm Metastasis
Human Embryonic Stem Cell-Derived Endothelial Cells as Cellular Delivery Vehicles for Treatment of Metastatic Breast Cancer.
Neoplasm Metastasis
Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo.
Neoplasm Metastasis
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
Neoplasm Metastasis
Inhibition of transforming growth factor-?-activated kinase-1 blocks cancer cell adhesion, invasion, and metastasis.
Neoplasm Metastasis
Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells.
Neoplasm Metastasis
Monitoring luciferase-labeled cancer cell growth and metastasis in different in vivo models.
Neoplasm Metastasis
Mouse model of lymph node metastasis via afferent lymphatic vessels for development of imaging modalities.
Neoplasm Metastasis
Multimodal fluorescence- and bioluminescence imaging reveals transfection potential of intratracheally administered polyplexes for breast cancer lung metastases.
Neoplasm Metastasis
Multimodality imaging of IL-18--binding protein-Fc therapy of experimental lung metastasis.
Neoplasm Metastasis
Multimodality imaging of TGF{beta} signaling in breast cancer metastases.
Neoplasm Metastasis
Overexpression of CXCR7 accelerates tumor growth and metastasis of lung cancer cells.
Neoplasm Metastasis
Reduction of tumor cell migration and metastasis by adenoviral gene transfer of plasminogen activator inhibitors.
Neoplasm Metastasis
Short-time focused ultrasound hyperthermia enhances liposomal doxorubicin delivery and antitumor efficacy for brain metastasis of breast cancer.
Neoplasm Metastasis
Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.
Neoplasm Metastasis
TMTP1-modified Indocyanine Green-loaded Polymeric Micelles for Targeted Imaging of Cervical Cancer and Metastasis Sentinel Lymph Node in vivo.
Neoplasm Metastasis
[Inhibitory effect of ONO-AE3-208 on the formation of bone metastasis of prostate cancer in mice].
Neoplasm Micrometastasis
The Transcription Factor SPDEF Suppresses Prostate Tumor Metastasis.
Neoplasms
2-(2-nitrobenzylidene) indolin-3-one compound inhibits transmembrane prostate androgen-induced protein (TMEPAI) expression and cancer cell proliferation.
Neoplasms
A gastrin transcript expressed in gastrointestinal cancer cells contains an internal ribosome entry site.
Neoplasms
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging.
Neoplasms
A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy.
Neoplasms
A novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells. Laboratory investigation.
Neoplasms
A novel xenograft mouse model for testing approaches targeting human kappa light-chain diseases.
Neoplasms
A tightly regulated and reversibly inducible siRNA expression system for conditional RNAi-mediated gene silencing in mammalian cells.
Neoplasms
A Unique Human Immunoglobulin Heavy Chain Variable Domain-Only CD33 CAR for the Treatment of Acute Myeloid Leukemia.
Neoplasms
Adenovirus-Mediated Transcriptional Targeting of Colorectal Cancer and Effects on Treatment-Resistant Hypoxic Cells.
Neoplasms
Adoptive immunotherapy mediated by ex vivo expanded natural killer T cells against CD1d-expressing lymphoid neoplasms.
Neoplasms
An optimized triple modality reporter for quantitative in vivo tumor imaging and therapy evaluation.
Neoplasms
Antibody-based tumor vascular theranostics targeting endosialin/TEM1 in a new mouse tumor vascular model.
Neoplasms
Application of molecular imaging technology in evaluating the inhibiting effect of apigenin in vivo on subcutaneous hepatocellular carcinoma.
Neoplasms
Artificial MicroRNAs as Novel Secreted Reporters for Cell Monitoring in Living Subjects.
Neoplasms
Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells.
Neoplasms
Bioluminescence imaging of a tumor-selective, thymidine kinase-defective vaccinia virus Guang9 strain after intratumoral or intraperitoneal administration in mice.
Neoplasms
Bioluminescence imaging of the response of rat gliosarcoma to ALA-PpIX-mediated photodynamic therapy.
Neoplasms
CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma.
Neoplasms
Central nervous system tumor immunity generated by a recombinant listeria monocytogenes vaccine targeting tyrosinase related protein-2 and real-time imaging of intracranial tumor burden.
Neoplasms
Characterization of thyroid cancer cell lines in murine orthotopic and intracardiac metastasis models.
Neoplasms
Combined E7-dendritic cell-based immunotherapy and human sodium/iodide symporter radioiodine gene therapy with monitoring of antitumor effects by bioluminescent imaging in a mouse model of uterine cervical cancer.
Neoplasms
Combined in vivo bioluminescence and fluorescence imaging for cancer gene therapy.
Neoplasms
Combined noninvasive imaging and luminometric quantification of luciferase-labeled human prostate tumors and metastases.
Neoplasms
Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors.
Neoplasms
Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs.
Neoplasms
Comparison of optical and power Doppler ultrasound imaging for non-invasive evaluation of arsenic trioxide as a vascular disrupting agent in tumors.
Neoplasms
Comparison of subcutaneous and intraperitoneal injection of D-luciferin for in vivo bioluminescence imaging.
Neoplasms
Comprehensive evaluation of the anti-angiogenic and anti-neoplastic effects of Endostar on liver cancer through optical molecular imaging.
Neoplasms
Correlating quantitative tumor accumulation and gene knockdown using SPECT/CT and bioluminescence imaging within an orthotopic ovarian cancer model.
Neoplasms
Correlation Between Epidermal Growth Factor Receptor-Specific Nanobody Uptake and Tumor Burden: A Tool for Noninvasive Monitoring of Tumor Response to Therapy.
Neoplasms
Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate.
Neoplasms
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Neoplasms
Development and comparison of novel bioluminescent mouse models of pancreatic neuroendocrine neoplasm metastasis.
Neoplasms
Different effect of paclitaxel on primary tumor mass, tumor cell contents, and metastases for four experimental human prostate tumors expressing luciferase.
Neoplasms
Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.
Neoplasms
Dual-modality monitoring of tumor response to cyclophosphamide therapy in mice with bioluminescence imaging and small-animal positron emission tomography.
Neoplasms
Dynamic bioluminescence and fluorescence imaging of the effects of the antivascular agent Combretastatin-A4P (CA4P) on brain tumor xenografts.
Neoplasms
Engineered Ferritin Nanoparticles for the Bioluminescence Tracking of Nanodrug Delivery in Cancer.
Neoplasms
Enhanced Anti-Tumor Efficacy through a Combination of Integrin ?v?6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition.
Neoplasms
Enhanced transgene expression and effective in vivo antitumor immune responses initiated by dendritic progenitors transfected with a nonviral T7 vector expressing a model tumor antigen.
Neoplasms
Estrogen receptor beta and the progression of prostate cancer: role of 5alpha-androstane-3beta,17beta-diol.
Neoplasms
Evaluation of chemical chaperones based on the monitoring of Bip promoter activity and visualization of extracellular vesicles by real-time bioluminescence imaging.
Neoplasms
Evaluation of Firefly Luciferase Bioluminescence Mediated Photodynamic Toxicity in Cancer Cells.
Neoplasms
Evaluation of firefly luciferase bioluminescence mediated photodynamic toxicity in cancer cells.
Neoplasms
Evaluation of Tumor Specificity and Immunity of Thymidine Kinase-Deleted Vaccinia Virus Guang9 Strain.
Neoplasms
Extended-release PEG-luciferin allows for long-term imaging of firefly luciferase activity in vivo.
Neoplasms
Formulation of photon diffusion from spherical bioluminescent sources in an infinite homogeneous medium.
Neoplasms
Gaussia Luciferase for Bioluminescence Tumor Monitoring in Comparison with Firefly Luciferase.
Neoplasms
Generation of Tumor Cells Expressing Firefly Luciferase (fLuc) to Evaluate the Effectiveness of CAR in a Murine Model.
Neoplasms
Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression.
Neoplasms
Glucosamine-Linked Near-Infrared Fluorescent Probes for Imaging of Solid Tumor Xenografts.
Neoplasms
High Sensitivity In Vivo Imaging of Cancer Metastasis Using a Near-Infrared Luciferin Analogue seMpai.
Neoplasms
Human adipose tissue-derived mesenchymal stromal cells as vehicles for tumor bystander effect: a model based on bioluminescence imaging.
Neoplasms
Hydrogen peroxide-mediated nuclear factor kappaB activation in both liver and tumor cells during initial stages of hepatic metastasis.
Neoplasms
IFN-? mediates graft-versus-breast cancer effects via enhancing cytotoxic T lymphocyte activity.
Neoplasms
Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds.
Neoplasms
Imaging gene expression in live transgenic mice after providing luciferin in drinking water.
Neoplasms
Imaging of Firefly Luciferase Activity under Antiangiogenic Therapy in a Heat Shock Protein 70-Transfected Melanoma Tumor Model.
Neoplasms
Imaging of Red-Shifted Light From Bioluminescent Tumors Using Fluorescence by Unbound Excitation From Luminescence.
Neoplasms
In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma.
Neoplasms
In Vivo Bioluminescence Imaging of Murine Xenograft Cancer Models with a Red-shifted Thermostable Luciferase.
Neoplasms
In Vivo Bioluminescence Imaging Validation of a Human Biopsy-derived Orthotopic Mouse Model of Glioblastoma Multiforme.
Neoplasms
In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene.
Neoplasms
In vivo imaging of colorectal cancer growth and metastasis by targeting MACC1 with shRNA in xenografted mice.
Neoplasms
In vivo monitoring of CD44+ cancer stem-like cells by ?-irradiation in breast cancer.
Neoplasms
Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses.
Neoplasms
Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer.
Neoplasms
Inhibition of androgen action by dehydroepiandrosterone sulfotransferase transfected in PC-3 prostate cancer cells.
Neoplasms
Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex.
Neoplasms
Intra-adrenal murine TH-MYCN neuroblastoma tumors grow more aggressive and exhibit a distinct tumor microenvironment relative to their subcutaneous equivalents.
Neoplasms
Intracranial elimination of human glioblastoma brain tumors in nude rats using the bispecific ligand-directed toxin, DTEGF13 and convection enhanced delivery.
Neoplasms
Intratumoral DNA electroporation induces anti-tumor immunity and tumor regression.
Neoplasms
Intravenously administered alphavirus vector VA7 eradicates orthotopic human glioma xenografts in nude mice.
Neoplasms
Investigation of oncogenic cooperation in simple liver-specific transgenic mouse models using noninvasive in vivo imaging.
Neoplasms
In vivo targeting of lentiviral vectors pseudotyped with the Tupaia paramyxovirus H glycoprotein bearing a cell-specific ligand.
Neoplasms
Long-term ex vivo and in vivo monitoring of tumor progression by using dual luciferases.
Neoplasms
Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo.
Neoplasms
Monitoring of tumour progression using bioluminescence imaging and computed tomography scanning in a nude mouse orthotopic model of human small cell lung cancer.
Neoplasms
Mucosal vascular addressin cell adhesion molecule-1 is expressed outside the endothelial lineage on fibroblasts and melanoma cells.
Neoplasms
Multimodal fluorescence- and bioluminescence imaging reveals transfection potential of intratracheally administered polyplexes for breast cancer lung metastases.
Neoplasms
Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer.
Neoplasms
Multimodality imaging methods for assessing retinoblastoma orthotopic xenograft growth and development.
Neoplasms
Murine tyrosinase expressed by a T7 vector in bone marrow-derived dendritic progenitors effectively prevents and eradicates melanoma tumors in mice.
Neoplasms
Non-invasive bioluminescence imaging to monitor the immunological control of a plasmablastic lymphoma-like B cell neoplasia after hematopoietic cell transplantation.
Neoplasms
Noninvasive bioluminescence imaging of luciferase expressing intracranial U87 xenografts: correlation with magnetic resonance imaging determined tumor volume and longitudinal use in assessing tumor growth and antiangiogenic treatment effect.
Neoplasms
Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy.
Neoplasms
Noninvasive imaging of transcriptionally restricted transgene expression following intratumoral injection of an adenovirus in which the COX-2 promoter drives a reporter gene.
Neoplasms
Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4.
Neoplasms
Noninvasive in vivo whole body luminescent analysis of luciferase labelled orthotopic prostate tumours.
Neoplasms
Noninvasive of adenovirus tumor retargeting in living subjects by a soluble adenovirus receptor-epidermal growth factor (sCAR-EGF) fusion protein.
Neoplasms
Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells.
Neoplasms
Oncolytic vesicular stomatitis viruses are potent agents for intravesical treatment of high-risk bladder cancer.
Neoplasms
Optical imaging: bacteria, viruses, and mammalian cells encoding light-emitting proteins reveal the locations of primary tumors and metastases in animals.
Neoplasms
Overexpression of CXCR7 accelerates tumor growth and metastasis of lung cancer cells.
Neoplasms
Peptide-Targeted Polyplexes for Aerosol-Mediated Gene Delivery to CD49f-Overexpressing Tumor Lesions in Lung.
Neoplasms
Persistence of High-Grade Cervical Dysplasia and Cervical Cancer Requires the Continuous Expression of the Human Papillomavirus Type 16 E7 Oncogene.
Neoplasms
Pharmacokinetic modeling of tumor bioluminescence implicates efflux, and not influx, as the bigger hurdle in cancer drug therapy.
Neoplasms
Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector.
Neoplasms
Preclinical evaluation of ex vivo expanded/activated gammadelta T cells for immunotherapy of glioblastoma multiforme.
Neoplasms
Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin.
Neoplasms
Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer.
Neoplasms
Prompt assessment of WST11-VTP outcome using luciferase transfected tumors enables second treatment and increase in overall therapeutic rate.
Neoplasms
Proteasome inhibitors reduce luciferase and beta-galactosidase activity in tissue culture cells.
Neoplasms
Quantitative in vivo bioluminescence imaging of orthotopic patient-derived glioblastoma xenografts.
Neoplasms
Rad51 promoter-targeted gene therapy is effective for in vivo visualization and treatment of cancer.
Neoplasms
Rapid obtention of stable, bioluminescent tumor cell lines using a tCD2-luciferase chimeric construct.
Neoplasms
Regression of experimental NIS-expressing breast cancer brain metastases in response to radioiodide/gemcitabine dual therapy.
Neoplasms
Repetitive, noninvasive imaging of cyclooxygenase-2 gene expression in living mice.
Neoplasms
Replacement of quaternary ammonium headgroups by tri-ornithine in cationic lipids for the improvement of gene delivery in vitro and in vivo.
Neoplasms
S6Ks isoforms contribute to viability, migration, docetaxel resistance and tumor formation of prostate cancer cells.
Neoplasms
Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase.
Neoplasms
Simultaneous imaging of temporal changes of NF-?B activity and viable tumor cells in Huh7/NF-?B-tk-luc2/rfp tumor-bearing mice.
Neoplasms
Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells.
Neoplasms
Suppression of the inflammatory response by disease-inducible interleukin-10 gene therapy in a three-dimensional micromass model of the human synovial membrane.
Neoplasms
Synergistic effects of host B7-H4 deficiency and gemcitabine treatment on tumor regression and anti-tumor T cell immunity in a mouse model.
Neoplasms
Systemic Delivery of an Oncolytic Adenovirus Expressing Soluble Transforming Growth Factor-? Receptor II-Fc Fusion Protein Can Inhibit Breast Cancer Bone Metastasis in a Mouse Model.
Neoplasms
Targeted Delivery of siRNA-Generating DNA Nanocassettes Using Multifunctional Nanoparticles.
Neoplasms
Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins.
Neoplasms
Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs).
Neoplasms
Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII-bearing tumor cells.
Neoplasms
Targeting trastuzumab-resistant breast cancer cells with a lentivirus engineered to bind antibodies that recognize HER-2.
Neoplasms
The effect of the bisphosphonate ibandronate on breast cancer metastasis to visceral organs.
Neoplasms
The expression level of luciferase within tumour cells can alter tumour growth upon in vivo bioluminescence imaging.
Neoplasms
The immune system prevents recurrence of transplanted but not autochthonous antigenic tumors after oncogene inactivation therapy.
Neoplasms
The use of recombinant adeno-associated viral vectors for the transduction of epithelial tumor cells.
Neoplasms
Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model.
Neoplasms
Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice.
Neoplasms
Transgenic mice that accept Luciferase- or GFP-expressing syngeneic tumor cells at high efficiencies.
Neoplasms
Tubulin-Destabilizing Agent BPR0L075 Induces Vascular-Disruption in Human Breast Cancer Mammary Fat Pad Xenografts.
Neoplasms
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Neoplasms
Using the Chicken Chorioallantoic Membrane In Vivo Model to Study Gynecological and Urological Cancers.
Neoplasms
Using [¹?F]FBAU for imaging brain tumor progression in an F98/tk-luc glioma-bearing rat model.
Neoplasms
Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals.
Neoplasms
Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells.
Neoplasms
Visualization of advanced human prostate cancer lesions in living mice by a targeted gene transfer vector and optical imaging.
Neoplasms
Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3.
Neoplasms
Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer.
Neoplasms
WISP1/CCN4: A Potential Target for Inhibiting Prostate Cancer Growth and Spread to Bone.
Neuroblastoma
Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b.
Neuroblastoma
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1? by inhibition of synthesis and not enhanced degradation.
Neuroblastoma
In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma.
Neuroma, Acoustic
Bioluminescent imaging of intracranial vestibular schwannoma xenografts in NOD/SCID mice.
Osteolysis
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Osteosarcoma
A 4.6 kb genomic duplication on 20p12.2-12.3 is associated with brachydactyly type A2 in a Chinese family.
Osteosarcoma
Advantages of bioluminescence imaging to follow siRNA or chemotherapeutic treatments in osteosarcoma preclinical models.
Ovarian Neoplasms
Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4.
Pancreatic Neoplasms
Extracellular DNA in pancreatic cancer promotes cell invasion and metastasis.
Pancreatic Neoplasms
Gemcitabine upregulates ABCG2/BCRP and modulates the intracellular pharmacokinetic profiles of bioluminescence in pancreatic cancer cells.
Parasitemia
Generation of stable L. major(+EGFP-LUC) and simultaneous comparison between EGFP and luciferase sensitivity.
Paratuberculosis
Development of a firefly luciferase-based assay for determining antimicrobial susceptibility of Mycobacterium avium subsp. paratuberculosis.
Parkinson Disease
alpha-Synuclein enhances bioluminescent activity of firefly luciferase by facilitating luciferin localization.
Pheochromocytoma
Insulin-like growth factor I increases rat peptide YY promoter activity through Sp1 binding sites.
Pneumonia
Pathology and immunogenicity in the cotton rat (Sigmodon hispidus) model after infection with a bovine adenovirus type 3 recombinant virus expressing the firefly luciferase gene.
Prolactinoma
[Melatonin inhibits the proliferation of pituitary prolactin-secreting tumor by suppressing the enhancer elements mutation of PRL gene in the rat]
Prostatic Neoplasms
CXCR4 inhibition enhances radiosensitivity, while inducing cancer cell mobilization in a prostate cancer mouse model.
Prostatic Neoplasms
H2 relaxin overexpression increases in vivo prostate xenograft tumor growth and angiogenesis.
Prostatic Neoplasms
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Prostatic Neoplasms
Molecular engineering of a two-step transcription amplification (TSTA) system for transgene delivery in prostate cancer.
Prostatic Neoplasms
Non-invasive imaging of firefly luciferase reporter gene expression using bioluminescence imaging in human prostate cancer models.
Prostatic Neoplasms
Poly(aminoether)-Gold Nanorod Assemblies for Plasmid shRNA-induced Gene Silencing.
Prostatic Neoplasms
Synthesis and in vitro preliminary evaluation of prostate-specific membrane antigen targeted upconversion nanoparticles as a first step towards radio/fluorescence-guided surgery of prostate cancer.
Prostatic Neoplasms
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
Prostatic Neoplasms
Two-step transcriptional amplification as a method for imaging reporter gene expression using weak promoters.
Prostatic Neoplasms
Unique angiogenic and vasculogenic properties of renal cell carcinoma in a xenograft model of bone metastasis are associated with high levels of vegf-a and decreased ang-1 expression.
Prostatic Neoplasms
[Inhibitory effect of ONO-AE3-208 on the formation of bone metastasis of prostate cancer in mice].
Pseudorabies
Firefly luciferase as a marker for herpesvirus (pseudorabies virus) replication in vitro and in vivo.
Pseudorabies
Recombinant Pseudorabies Virus (PRV) Expressing Firefly Luciferase Effectively Screened for CRISPR/Cas9 Single Guide RNAs and Antiviral Compounds.
Puberty, Precocious
A novel mutation of estrogen receptor gene detected in girls with precocious puberty.
Rabies
Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain.
Rabies
Novel, rapid assay for measuring entry of diverse enveloped viruses, including HIV and rabies.
Reperfusion Injury
Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model.
Sarcoma, Avian
Effect of intercistronic length on internal ribosome entry site (IRES) efficiency in bicistronic mRNA.
Sarcoma, Avian
Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.
Sarcoma, Avian
Prior arterial injury enhances luciferase expression following in vivo gene transfer.
Sarcoma, Avian
The efficiency of different IRESs (internal ribosomes entry site) in monocistronic mRNAS.
Scoliosis
Prolonged down regulation of specific gene expression in nucleus pulposus cell mediated by RNA interference in vitro.
Sepsis
Anti-inflammatory activity of curcumin-loaded solid lipid nanoparticles in IL-1? transgenic mice subjected to the lipopolysaccharide-induced sepsis.
Sepsis
Streptococcus pneumoniae elaborates persistent and prolonged competent state during pneumonia-derived sepsis.
Severe Combined Immunodeficiency
Interrogating androgen receptor function in recurrent prostate cancer.
Severe Combined Immunodeficiency
Noninvasive assessment of tumor cell proliferation in animal models.
Severe Combined Immunodeficiency
Nuclear expression of S100A4 calcium binding protein increases cholangiocarcinoma invasiveness and metastasization.
Severe Combined Immunodeficiency
Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.
Smallpox
Bioluminescent imaging of vaccinia virus infection in immunocompetent and immunodeficient rats as a model for human smallpox.
Squamous Cell Carcinoma of Head and Neck
A nonviral vector with transfection activity comparable with adenoviral transduction.
Stomach Neoplasms
Development of a cell-based pathway modulator screening system to screen the targeted cancer therapeutic candidates.
Stomach Neoplasms
Identification of the targeted therapeutic potential of doxycycline for a subset of gastric cancer patients.
Stomach Neoplasms
Non-invasive visualisation of the development of peritoneal carcinomatosis and tumour regression after 213Bi-radioimmunotherapy using bioluminescence imaging.
Stomach Neoplasms
Noninvasive visualization of microRNA-16 in the chemoresistance of gastric cancer using a dual reporter gene imaging system.
Tauopathies
Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone.
Teratoma
Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma.
Thyroid Cancer, Papillary
Characterization of thyroid cancer cell lines in murine orthotopic and intracardiac metastasis models.
Thyroid Neoplasms
Characterization of thyroid cancer cell lines in murine orthotopic and intracardiac metastasis models.
Triple Negative Breast Neoplasms
Longitudinal Visualization of Viable Cancer Cell Intratumoral Distribution in Mouse Models Using Oatp1a1-Enhanced Magnetic Resonance Imaging.
Triple Negative Breast Neoplasms
Multimodal fluorescence- and bioluminescence imaging reveals transfection potential of intratracheally administered polyplexes for breast cancer lung metastases.
Tuberculosis
A novel firefly luciferase biosensor enhances the detection of apoptosis induced by ESAT-6 family proteins of Mycobacterium tuberculosis.
Tuberculosis
A rapid method for screening antimicrobial agents for activities against a strain of Mycobacterium tuberculosis expressing firefly luciferase.
Tuberculosis
Antibiotic-dependent correlation between drug-induced killing and loss of luminescence in Streptococcus gordonii expressing luciferase.
Tuberculosis
Construction and evaluation of luciferase reporter phages for the detection of active and non-replicating tubercle bacilli.
Tuberculosis
Rapid in vivo assessment of drug efficacy against Mycobacterium tuberculosis using an improved firefly luciferase.
Tuberculosis
Reporter gene technology to assess activity of antimycobacterial agents in macrophages.
Urinary Bladder Neoplasms
A validated mouse model for orthotopic bladder cancer using transurethral tumour inoculation and bioluminescence imaging.
Urinary Bladder Neoplasms
Cloning and analysis of human UroplakinII promoter and its application for gene therapy in bladder cancer.
Urinary Bladder Neoplasms
Intravesical chemotherapy of high-grade bladder cancer with HTI-286, a synthetic analogue of the marine sponge product hemiasterlin.
Urinary Bladder Neoplasms
Oncolytic vesicular stomatitis viruses are potent agents for intravesical treatment of high-risk bladder cancer.
Uterine Cervical Neoplasms
Combined E7-dendritic cell-based immunotherapy and human sodium/iodide symporter radioiodine gene therapy with monitoring of antitumor effects by bioluminescent imaging in a mouse model of uterine cervical cancer.
Uterine Cervical Neoplasms
TMTP1-modified Indocyanine Green-loaded Polymeric Micelles for Targeted Imaging of Cervical Cancer and Metastasis Sentinel Lymph Node in vivo.
Vaccinia
A modified HIV challenge assay in mice by using luciferase-expressing vaccinia virus.
Vaccinia
A mouse model based on replication-competent Tiantan vaccinia expressing luciferase/HIV-1 Gag fusion protein for the evaluation of protective efficacy of HIV vaccine.
Vaccinia
Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant.
Vaccinia
Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread.
Vaccinia
Bioluminescent imaging of vaccinia virus infection in immunocompetent and immunodeficient rats as a model for human smallpox.
Vaccinia
Comparison of the replication characteristics of vaccinia virus strains Guang 9 and Tian Tan in vivo and in vitro.
Vaccinia
Evaluation of Tumor Specificity and Immunity of Thymidine Kinase-Deleted Vaccinia Virus Guang9 Strain.
Vaccinia
Expression of the firefly luciferase gene in vaccinia virus: a highly sensitive gene marker to follow virus dissemination in tissues of infected animals.
Vaccinia
Regional versus systemic delivery of recombinant vaccinia virus as suicide gene therapy for murine liver metastases.
Vaccinia
Screening and evaluation of potential inhibitors against vaccinia virus from 767 approved drugs.
Vaccinia
Tumor-specific gene delivery using recombinant vaccinia virus in a rabbit model of liver metastases.
Vaccinia
[Analysis of reporter gene expression at different segments of the vaccinia virus genome]
Vesicular Stomatitis
A vesicular stomatitis virus replicon-based bioassay for the rapid and sensitive determination of multi-species type I interferon.
Vesicular Stomatitis
Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain.
Vesicular Stomatitis
Fetal gene transfer using lentiviral vectors: in vivo detection of gene expression by microPET and optical imaging in fetal and infant monkeys.
Vesicular Stomatitis
High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G.
Virus Diseases
Bioluminescence imaging of vaccinia virus: effects of interferon on viral replication and spread.
Virus Diseases
Circadian regulation of a viral gene promoter in live transgenic mice expressing firefly luciferase.
Virus Diseases
Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice.
Virus Diseases
Oncolytic herpes simplex virus counteracts the hypoxia-induced modulation of glioblastoma stem-like cells.
Virus Diseases
Tricyclo-DNA containing oligonucleotides as steric block inhibitors of human immunodeficiency virus type 1 tat-dependent trans-activation and HIV-1 infectivity.
Yellow Fever
Construction of yellow fever virus subgenomic replicons by yeast-based homologous recombination cloning technique.
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