Reference on EC 1.13.12.5 - Renilla-type luciferase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cormier, M.J.; Hori, K.; Anderson, J.M.
Bioluminescence in coelenterates
Biochim. Biophys. Acta
346
137-164
1974
Renilla koellikeri, Renilla muelleri, Renilla reniformis
Matthews, J.C.; Hori, K.; Cormier, M.J.
Purification and properties of Renilla reniformis luciferase
Biochemistry
16
85-91
1977
Renilla reniformis
DeLuca, M.; Dempsey, M.E.; Hori, K.; Wampler, J.E.; Cormier, M.J.
Mechanism of oxidative carbon dioxide production during Renilla reniformis bioluminescence
Proc. Natl. Acad. Sci. USA
68
1658-1660
1971
Renilla reniformis
Hart, R.C.; Matthews, J.C.; Hori, K.; Cormier, M.J.
Renilla reniformis bioluminescence: luciferase-catalyzed production of nonradiating excited states from luciferin analogues and elucidation of the excited state species involved in energy transfer to Renilla green fluorescent protein
Biochemistry
18
2204-2210
1979
Renilla reniformis
Matthews, J.C.; Hori, K.; Cormier, M.J.
Substrate and substrate analogue binding properties of Renilla luciferase
Biochemistry
16
5217-5220
1977
Renilla reniformis
Karkhanis, Y.D.; Cormier, M.J.
Isolation and properties of Renilla reniformis luciferase, a low molecular weight energy conversion enzyme
Biochemistry
10
317-326
1971
Renilla reniformis
Liu, J.; Escher, A.
Improved assay sensitivity of an engineered secreted Renilla luciferase
Gene
237
153-159
1999
Renilla reniformis
Liu, J.; O'Kane, D.J.; Escher, A.
Secretion of functional Renilla reniformis luciferase by mammalian cells
Gene
203
141-148
1997
Renilla reniformis
Bhaumik, S.; Lewis, X.Z.; Gambhir, S.S.
Optical imaging of Renilla luciferase, synthetic Renilla luciferase, and firefly luciferase reporter gene expression in living mice
J. Biomed. Opt.
9
578-586
2004
Renilla reniformis
Zhao, H.; Doyle, T.C.; Wong, R.J.; Cao, Y.; Stevenson, D.K.; Piwnica-Worms, D.; Contag, C.H.
Characterization of coelenterazine analogs for measurements of Renilla luciferase activity in live cells and living animals
Mol. Imaging
3
43-54
2004
Renilla reniformis
Mulholland, D.J.; Cox, M.; Read, J.; Rennie, P.; Nelson, C.
Androgen responsiveness of Renilla luciferase reporter vectors is promoter, transgene, and cell line dependent
Prostate
59
115-119
2004
Renilla reniformis
Roberts, R.; Yount, B.; Sims, A.; Baker, S.; Baric, R.
Renilla luciferase as a reporter to assess SARS-CoV mRNA transcription regulation and efficacy of anti-SARS-CoV agents
Adv. Exp. Med. Biol.
581
597-600
2006
Renilla sp.
Deo, S.K.; Mirasoli, M.; Daunert, S.
Bioluminescence resonance energy transfer from aequorin to a fluorophore: an artificial jellyfish for applications in multianalyte detection
Anal. Bioanal. Chem.
381
1387-1394
2005
Aequorea victoria
Dyer, B.W.; Ferrer, F.A.; Klinedinst, D.K.; Rodriguez, R.
A noncommercial dual luciferase enzyme assay system for reporter gene analysis
Anal. Biochem.
282
158-161
2000
Renilla reniformis
Inouye, S.; Tsuji, F.I.
Cloning and sequence analysis of cDNA for the Ca2+-activated photoprotein, clytin
FEBS Lett.
315
343-346
1993
Clytia gregaria
Inouye, S.
Blue fluorescent protein from the calcium-sensitive photoprotein aequorin is a heat resistant enzyme, catalyzing the oxidation of coelenterazine
FEBS Lett.
577
105-110
2004
Aequorea forskalea
Inouye, S.; Sasaki, S.
Blue fluorescent protein from the calcium-sensitive photoprotein aequorin: catalytic properties for the oxidation of coelenterazine as an oxygenase
FEBS Lett.
580
1977-1982
2006
Aequorea forskalea
Cheung, C.Y.; Webb, S.E.; Meng, A.; Miller, A.L.
Transient expression of apoaequorin in zebrafish embryos: extending the ability to image calcium transients during later stages of development
Int. J. Dev. Biol.
50
561-569
2006
Aequorea forskalea
Ohashi, W.; Inouye, S.; Yamazaki, T.; Hirota, H.
NMR analysis of the Mg2+-binding properties of aequorin, a Ca2+-binding photoprotein
J. Biochem.
138
613-620
2005
Aequorea forskalea
Tsuzuki, K.; Tricoire, L.; Courjean, O.; Gibelin, N.; Rossier, J.; Lambolez, B.
Thermostable mutants of the photoprotein aequorin obtained by in vitro evolution
J. Biol. Chem.
280
34324-34331
2005
Aequorea victoria (Q6J4T7)
Tricoire, L.; Tsuzuki, K.; Courjean, O.; Gibelin, N.; Bourout, G.; Rossier, J.; Lambolez, B.
Calcium dependence of aequorin bioluminescence dissected by random mutagenesis
Proc. Natl. Acad. Sci. USA
103
9500-9505
2006
Aequorea victoria
Loening, A.M.; Fenn, T.D.; Wu, A.M.; Gambhir, S.S.
Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output
Protein Eng. Des. Sel.
19
391-400
2006
Renilla sp.
Venisnik, K.M.; Olafsen, T.; Loening, A.M.; Iyer, M.; Gambhir, S.S.; Wu, A.M.
Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors
Protein Eng. Des. Sel.
19
453-460
2006
Renilla sp.
Inouye, S.; Sshara, Y.
Expression, purification and characterization of a photoprotein, clytin, from Clytia gregarium
Protein Expr. Purif.
53
384-389
2007
Clytia gregaria
Deng, L.; Vysotski, E.S.; Markova, S.V.; Liu, Z.J.; Lee, J.; Rose, J.; Wang, B.C.
All three Ca2+-binding loops of photoproteins bind calcium ions: the crystal structures of calcium-loaded apo-aequorin and apo-obelin
Protein Sci.
14
663-675
2005
Aequorea victoria (P07164)
Hanson, J.; Reese, J.; Gorman, J.; Cash, J.; Fraizer, G.
Hormone treatment enhances WT1 activation of renilla luciferase constructs in LNCaP cells
Front. Biosci.
12
1387-1394
2007
Renilla reniformis
Auld, D.S.; Southall, N.T.; Jadhav, A.; Johnson, R.L.; Diller, D.J.; Simeonov, A.; Austin, C.P.; Inglese, J.
Characterization of chemical libraries for luciferase inhibitory activity
J. Med. Chem.
51
2372-2386
2008
Renilla reniformis
Loening, A.M.; Fenn, T.D.; Gambhir, S.S.
Crystal structures of the luciferase and green fluorescent protein from Renilla reniformis
J. Mol. Biol.
374
1017-1028
2007
Renilla reniformis (P27652)
Hoshino, H.; Nakajima, Y.; Ohmiya, Y.
Luciferase-YFP fusion tag with enhanced emission for single-cell luminescence imaging
Nat. Methods
4
637-639
2007
Renilla reniformis
Titushin, M.S.; Markova, S.V.; Frank, L.A.; Malikova, N.P.; Stepanyuk, G.A.; Lee, J.; Vysotski, E.S.
Coelenterazine-binding protein of Renilla muelleri: cDNA cloning, overexpression, and characterization as a substrate of luciferase
Photochem. Photobiol. Sci.
7
189-196
2008
Renilla muelleri (C9V492), Renilla muelleri
Woo, J.; Howell, M.H.; von Arnim, A.G.
Structure-function studies on the active site of the coelenterazine-dependent luciferase from Renilla
Protein Sci.
17
725-735
2008
Renilla reniformis (P27652)
Andou, T.; Endoh, T.; Mie, M.; Kobatake, E.
RNA detection using peptide-inserted Renilla luciferase
Anal. Bioanal. Chem.
393
661-668
2009
Renilla sp.
Verhaegen, M.; Christopoulos, T.
Recombinant Gaussia luciferase: Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization
Anal. Chem.
74
4378-4385
2002
Gaussia princeps (Q9BLZ2), Gaussia princeps
Maguire, C.; Deliolanis, N.; Pike, L.; Niers, J.; Tjon-Kon-Fat, L.; Sena-Esteves, M.; Tannous, B.
Gaussia luciferase variant for high-throughput functional screening applications
Anal. Chem.
81
7102-7106
2009
Gaussia princeps
Kaihara, A.; Umezawa, Y.; Furukawa, T.
Bioluminescent indicators for Ca2+ based on split renilla luciferase complementation in living cells
Anal. Sci.
24
1405-1408
2008
Renilla sp.
Inouye, S.; Sahara, Y.
Identification of two catalytic domains in a luciferase secreted by the copepod Gaussia princeps
Biochem. Biophys. Res. Commun.
365
96-101
2008
Gaussia princeps
Patel, K.; Ng, P.; Kuo, C.; Levy, S.; Levy, R.; Swartz, J.
Cell-free production of Gaussia princeps luciferase - antibody fragment bioconjugates for ex vivo detection of tumor cells
Biochem. Biophys. Res. Commun.
390
971-976
2009
Gaussia princeps
Cissell, K.A.; Rahimi, Y.; Shrestha, S.; Deo, S.K.
Reassembly of a bioluminescent protein renilla luciferase directed through DNA hybridization
Bioconjug. Chem.
20
15-19
2009
Renilla sp.
Suzuki, T.; Usuda, S.; Ichinose, H.; Inouye, S.
Real-time bioluminescence imaging of a protein secretory pathway in living mammalian cells using Gaussia luciferase
FEBS Lett.
581
4551-4556
2007
Gaussia princeps
Liu, X.; Kramer, J.A.; Hu, Y.; Schmidt, J.M.; Jiang, J.; Wilson, A.G.E.
Development of a high-throughput human hepG2 dual luciferase assay for detection of metabolically activated hepatotoxicants and genotoxicants
Int. J. Toxicol.
28
162-179
2009
Renilla sp.
Knappskog, S.; Ravneberg, H.; Gjerdrum, C.; Tre, C.; Stern, B.; Pryme, I.
The level of synthesis and secretion of Gaussia princeps luciferase in transfected CHO cells is heavily dependent on the choice of signal peptide
J. Biotechnol.
128
705-715
2007
Gaussia princeps (Q9BLZ2), Gaussia princeps
Ruecker, O.; Zillner, K.; Groebner-Ferreira, R.; Heitzer, M.
Gaussia-luciferase as a sensitive reporter gene for monitoring promoter activity in the nucleus of the green alga Chlamydomonas reinhardtii
Mol. Genet. Genomics
280
153-162
2008
Renilla sp., Gaussia princeps (Q9BLZ2), Gaussia princeps
Santos, E.B.; Yeh, R.; Lee, J.; Nikhamin, Y.; Punzalan, B.; Punzalan, B.; La Perle, K.; Larson, S.M.; Sadelain, M.; Brentjens, R.J.
Sensitive in vivo imaging of T cells using a membrane-bound Gaussia princeps luciferase
Nat. Med.
15
338-344
2009
Renilla sp., Gaussia princeps
Woo, J.; v. Arnim, A.G.
Mutational optimization of the coelenterazine-dependent luciferase from Renilla
Plant Methods
4
23
2008
Renilla reniformis
Herbst, K.J.; Allen, M.D.; Zhang, J.
The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by renilla luciferase
Plos One
4
e5642
2009
Renilla sp.
Badr, C.; Hewett, J.; Breakefield, X.; Tannous, B.
A highly sensitive assay for monitoring the secretory pathway and ER stress
PLoS ONE
6
e571
2007
Gaussia princeps
Auld, D.S.; Thorne, N.; Maguire, W.F.; Inglese, J.
Mechanism of PTC124 activity in cell-based luciferase assay of nonsense codon suppression
Proc. Natl. Acad. Sci. USA
106
3585-3590
2009
Renilla reniformis
Stepanyuk, G.A.; Unch, J.; Malikova, N.P.; Markova, S.V.; Lee, J.; Vysotski, E.S.
Coelenterazine-v ligated to Ca2+-triggered coelenterazine-binding protein is a stable and efficient substrate of the red-shifted mutant of Renilla muelleri luciferase
Anal. Bioanal. Chem.
398
1809-1817
2010
Renilla muelleri (C9V492), Renilla muelleri
Liu, S.; Nelson, C.A.; Xiao, L.; Lu, L.; Seth, P.P.; Davis, D.R.; Hagedorn, C.H.
Measuring antiviral activity of benzimidazole molecules that alter IRES RNA structure with an infectious hepatitis C virus chimera expressing Renilla luciferase
Antiviral Res.
89
54-63
2010
Renilla reniformis
Jiang, Y.; Bernard, D.; Yu, Y.; Xie, Y.; Zhang, T.; Li, Y.; Burnett, J.P.; Fu, X.; Wang, S.; Sun, D.
Split Renilla luciferase protein fragment-assisted complementation (SRL-PFAC) to characterize Hsp90-Cdc37 complex and identify critical residues in protein/protein interactions
J. Biol. Chem.
285
21023-21036
2010
Renilla reniformis
Huang, H.; Choi, S.Y.; Frohman, M.A.
A quantitative assay for mitochondrial fusion using Renilla luciferase complementation
Mitochondrion
10
559-566
2010
Renilla reniformis
Hatzios, S.; Ringgaard, S.; Davis, B.; Waldor, M.
Studies of dynamic protein-protein interactions in bacteria using renilla luciferase complementation are undermined by nonspecific enzyme inhibition
PLoS ONE
7
e43175
2012
Renilla reniformis
Inouye, S.; Sahara-Miura, Y.; Sato, J.; Iimori, R.; Yoshida, S.; Hosoya, T.
Expression, purification and luminescence properties of coelenterazine-utilizing luciferases from Renilla, Oplophorus and Gaussia: comparison of substrate specificity for C2-modified coelenterazines
Protein Expr. Purif.
88
150-156
2013
Gaussia, Oplophorus gracilirostris, Renilla reniformis
Song, W.C.; Sung, H.J.; Park, K.S.; Choi, J.W.; Cho, J.Y.; Um, S.H.
Novel functional Renilla luciferase mutant provides long-term serum stability and high luminescence activity
Protein Expr. Purif.
91
215-220
2013
Renilla reniformis
Wang, J.; Guo, W.; Long, C.; Zhou, H.; Wang, H.; Sun, X.
The split Renilla luciferase complementation assay is useful for identifying the interaction of Epstein-Barr virus protein kinase BGLF4 and aheat shock protein Hsp90
Acta Virol.
60
62-70
2016
Renilla reniformis (P27652)
Farzannia, A.; Roghanian, R.; Zarkesh-Esfahani, S.H.; Nazari, M.; Emamzadeh, R.
FcUni-RLuc an engineered Renilla luciferase with Fc binding ability and light emission activity
Analyst
140
1438-1441
2015
Renilla reniformis (P27652)
Ghaedizadeh, S.; Emamzadeh, R.; Nazari, M.; Rasa, S.; Zarkesh-Esfahani, S.; Yousefi, M.
Understanding the molecular behaviour of Renilla luciferase in imidazolium-based ionic liquids, a new model for the alpha/beta fold collapse
Biochem. Eng. J.
105
505-513
2016
Renilla reniformis (P27652)
-
Fanaei Kahrani, Z.; Emamzadeh, R.; Nazari, M.; Rasa, S.M.
Molecular basis of thermostability enhancement of Renilla luciferase at higher temperatures by insertion of a disulfide bridge into the structure
Biochim. Biophys. Acta
1865
252-259
2017
Renilla reniformis (P27652)
Rahnama, S.; Saffar, B.; Kahrani, Z.F.; Nazari, M.; Emamzadeh, R.
Super RLuc8 A novel engineered Renilla luciferase with a red-shifted spectrum and stable light emission
Enzyme Microb. Technol.
96
60-66
2017
Renilla reniformis (P27652)
Salehi, F.; Emamzadeh, R.; Nazari, M.; Rasa, S.M.
Probing the emitter site of Renilla luciferase using small organic molecules; an attempt to understand the molecular architecture of the emitter site
Int. J. Biol. Macromol.
93
1253-1260
2016
Renilla reniformis (P27652)
Liyaghatdar, Z.; Emamzadeh, R.; Rasa, S.M.M.; Nazari, M.
Trehalose radial networks protect Renilla luciferase helical layers against thermal inactivation
Int. J. Biol. Macromol.
105
66-73
2017
Renilla reniformis (P27652), Renilla reniformis
Kahrani, Z.F.; Ganjalikhany, M.R.; Rasa, S.M.M.; Emamzadeh, R.
New Insights into the Molecular characteristics behind the function of Renilla luciferase
J. Cell. Biochem.
119
1780-1790
2018
Renilla reniformis (P27652)
Farkas, T.; Jaeaettelae, M.
Renilla luciferase-LC3 based reporter assay for measuring autophagic flux
Methods Enzymol.
588
1-13
2017
Renilla reniformis (P27652)
Jiang, T.; Yang, X.; Yang, X.; Yuan, M.; Zhang, T.; Zhang, H.; Li, M.
Novel bioluminescent coelenterazine derivatives with imidazopyrazinone C-6 extended substitution for Renilla luciferase
Org. Biomol. Chem.
14
5272-5281
2016
Renilla reniformis (P27652)
Shigehisa, M.; Amaba, N.; Arai, S.; Higashi, C.; Kawanabe, R.; Matsunaga, A.; Laksmi, F.A.; Tokunaga, M.; Ishibashi, M.
Stabilization of luciferase from Renilla reniformis using random mutations
Protein Eng. Des. Sel.
30
7-13
2017
Renilla reniformis (P27652)
Broyles, D.B.; Dikici, E.; Daunert, S.; Deo, S.K.
Facile synthesis and characterization of a novel tamavidin-luciferase reporter fusion protein for universal signaling applications
Adv. Biosyst.
4
e1900166
2020
Gaussia princeps (Q9BLZ2)
Khoshnevisan, G.; Emamzadeh, R.; Nazari, M.; Rasa, S.M.M.; Sariri, R.; Hassani, L.
Kinetics, structure, and dynamics of Renilla luciferase solvated in binary mixtures of glycerol and water and the mechanism by which glycerol obstructs the enzyme emitter site
Int. J. Biol. Macromol.
117
617-624
2018
Renilla reniformis (CAA01908.1)
Larionova, M.; Markova, S.; Vysotski, E.
Bioluminescent and structural features of native folded Gaussia luciferase
J. Photochem. Photobiol. B
183
309-317
2018
Gaussia princeps (Q9BLZ2), Gaussia princeps
Zhang, C.; Cheng, L.; Dong, G.; Han, G.; Yang, X.; Tang, C.; Li, X.; Zhou, Y.; Du, L.; Li, M.
Novel photoactivatable substrates for Renilla luciferase imaging in vitro and in vivo
Org. Biomol. Chem.
16
4789-4792
2018
Renilla sp.
Ishibashi, M.; Kawanabe, R.; Amaba, N.; Arai, S.; Laksmi, F.; Komori, K.; Tokunaga, M.
Expression and characterization of the Renilla luciferase with the cumulative mutation
Protein Expr. Purif.
145
39-44
2018
Renilla reniformis (P27652), Renilla reniformis
Wu, N.; Kobayashi, N.; Tsuda, K.; Unzai, S.; Saotome, T.; Kuroda, Y.; Yamazaki, T.
Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR
Sci. Rep.
10
20069
2020
Gaussia princeps (Q9BLZ2)
html completed
