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Disease on EC 1.13.12.13 - Oplophorus-luciferin 2-monooxygenase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Amyotrophic Lateral Sclerosis
A highly sensitive assay of IRE1 activity using the small luciferase NanoLuc: Evaluation of ALS-related genetic and pathological factors.
SOD1 dimerization monitoring using a novel split NanoLuc, NanoBit.
Arthritis
Bioluminescent Ross River Virus Allows Live Monitoring of Acute and Long-Term Alphaviral Infection by In Vivo Imaging.
Border Disease
Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag.
Brain Neoplasms
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Breast Neoplasms
Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET.
Bronchitis
Development of HiBiT-Tagged Recombinant Infectious Bronchitis Coronavirus for Efficient in vitro and in vivo Viral Quantification.
Carcinogenesis
A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Carcinoma, Hepatocellular
Apaf1 nanoLuc biosensors identified lentinan as a potent synergizer of cisplatin in targeting hepatocellular carcinoma cells.
Novel reporter system to monitor early stages of the hepatitis B virus life cycle.
Cholangiocarcinoma
Discovery of a chemical compound that suppresses expression of BEX2, a dormant cancer stem cell-related protein.
Classical Swine Fever
Development of a High-Throughput Serum Neutralization Test Using Recombinant Pestiviruses Possessing a Small Reporter Tag.
Colonic Neoplasms
Using ?-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway.
Cysts
Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model.
Dermatitis, Phototoxic
Phototoxicity of flavoprotein miniSOG induced by bioluminescence resonance energy transfer in genetically encoded system NanoLuc-miniSOG is comparable with its LED-excited phototoxicity.
Distemper
Recovery of NanoLuc Luciferase-Tagged Canine Distemper Virus for Facilitating Rapid Screening of Antivirals in vitro.
Encephalitis, Japanese
In vivo dynamics of reporter Flaviviridae viruses.
Fragile X Syndrome
One-Step Generation of Seamless Luciferase Gene Knockin Using CRISPR/Cas9 Genome Editing in Human Pluripotent Stem Cells.
Glioblastoma
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Hepatitis B
Novel reporter system to monitor early stages of the hepatitis B virus life cycle.
Hepatitis C
In vivo dynamics of reporter Flaviviridae viruses.
Infections
A sensitive and reproducible cell-based assay via secNanoLuc to detect neutralizing antibody against adeno-associated virus vector capsid.
Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
Identification of KX2-391 as an inhibitor of HBV transcription by a recombinant HBV-based screening assay.
In Vivo Live Imaging of Oncolytic Mammalian Orthoreovirus Expressing NanoLuc Luciferase in Tumor Xenograft Mice.
NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice-A Novel in Vivo Imaging Platform.
Nanoluciferase-Based Method for Detecting Gene Expression in Caenorhabditis elegans.
Recombinant Hepatitis E Viruses Harboring Tags in the ORF1 Protein.
T cell-derived interferon-? is required for host defense to Toxoplasma gondii.
The Vaginal Acquisition and Dissemination of HIV-1 Infection in a Novel Transgenic Mouse Model Is Facilitated by Coinfection with Herpes Simplex Virus 2 and Is Inhibited by Microbicide Treatment.
Influenza, Human
A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection.
Replication-Competent ?NS1 Influenza A Viruses Expressing Reporter Genes.
Visualizing real-time influenza virus infection, transmission and protection in ferrets.
Leishmaniasis, Cutaneous
Evaluation of NanoLuc, RedLuc and Luc2 as bioluminescent reporters in a cutaneous leishmaniasis model.
Leukemia
Nanoluciferase as a novel quantitative protein fusion tag: Application for overexpression and bioluminescent receptor-binding assays of human leukemia inhibitory factor.
Melanoma, Experimental
The influences of a novel anti-adhesion device, thermally cross-linked gelatin film on peritoneal dissemination of tumor cells: The in vitro and in vivo experiments using murine carcinomatous peritonitis models.
Metrorrhagia
Development of a Paper-Based Luminescence Bioassay for Therapeutic Monitoring of Aminoglycosides: a Proof-of-Concept Study.
Neoplasm Metastasis
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Neoplasms
A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells.
A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Detection of Brain Tumors and Systemic Metastases Using NanoLuc and Fluc for Dual Reporter Imaging.
Evaluation of chemical chaperones based on the monitoring of Bip promoter activity and visualization of extracellular vesicles by real-time bioluminescence imaging.
Flavoprotein miniSOG Cytotoxisity Can Be Induced By Bioluminescence Resonance Energy Transfer.
In Vivo Live Imaging of Oncolytic Mammalian Orthoreovirus Expressing NanoLuc Luciferase in Tumor Xenograft Mice.
pHLuc, a Ratiometric Luminescent Reporter for in vivo Monitoring of Tumor Acidosis.
Phototoxicity of flavoprotein miniSOG induced by bioluminescence resonance energy transfer in genetically encoded system NanoLuc-miniSOG is comparable with its LED-excited phototoxicity.
The influences of a novel anti-adhesion device, thermally cross-linked gelatin film on peritoneal dissemination of tumor cells: The in vitro and in vivo experiments using murine carcinomatous peritonitis models.
Neuroblastoma
Molecular Function Analysis of Rabies Virus RNA Polymerase L Protein by Using an L Gene-Deficient Virus.
Pseudorabies
A NanoLuc Luciferase Reporter Pseudorabies Virus for Live Imaging and Quantification of Viral Infection.
Rabies
Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
Uterine Cervical Neoplasms
Using ?-Lactamase and NanoLuc Luciferase Reporter Gene Assays to Identify Inhibitors of the HIF-1 Signaling Pathway.
Virus Diseases
A NanoLuc Luciferase Reporter Pseudorabies Virus for Live Imaging and Quantification of Viral Infection.
Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays.
Highly sensitive real-time in vivo imaging of an influenza reporter virus reveals dynamics of replication and spread.
Yellow Fever
Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery.