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Information on EC 1.13.11.77 - oleate 10S-lipoxygenase

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IUBMB Comments
Binds Fe2+. The enzyme isolated from the bacterium Pseudomonas sp. 42A2 has similar activity with all the three Delta9 fatty acids. cf. EC 1.13.11.62, linoleate 10R-lipoxygenase.
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Word Map
  • 1.13.11.77
  • bristle
  • wingless
  • glypicans
  • proneural
  • pannier
  • decapentaplegic
  • achaete-scute
  • deacylase
  • dally
  • macrochaete
  • prepatterning
  • iroquois
  • dally-like
  • palmitoleoylate
  • notal
The enzyme appears in viruses and cellular organisms
Synonyms
(10S)-dioxygenase, (10S)-DOX, 10S-dioxygenase, 10S-DOX, heme dioxygenase, linoleate 10S-dioxygenase, linoleate 10S-DOX, linoleate heme 10S-dioxygenase, LOX, Np-diox, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
alpha-linolenate + O2 = (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate
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(3)
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linoleate + O2 = (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate
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(2)
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oleate + O2 = (8E,10S)-10-hydroperoxyoctadeca-8-enoate
show the reaction diagram
(1)
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