Any feedback?
Information on EC 1.13.11.68 - 9-cis-beta-carotene 9',10'-cleaving dioxygenase
for references in articles please use BRENDA:EC1.13.11.68Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
1.13.11.68 9-cis-beta-carotene 9',10'-cleaving dioxygenaseIUBMB Comments
Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza.
Specify your search results
Word Map
- 1.13.11.68
- strigolactones
- sls
- shoot
-
phytohormone
-
axillary
- dwarf27
-
tillering
- carlactone
-
weed
-
carotenoid-derived
-
apocarotenoids
- phelipanche
- ramosa
- orobanche
-
arbuscular
The enzyme appears in viruses and cellular organisms
Synonyms
atccd7, ccd4b, carotenoid cleavage dioxygenase 7, carotenoid cleavage dioxygenases 7, osccd7, max3/ccd7, zmccd7, sl biosynthetic enzyme, psccd7, zpccd7, 
more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
AtCCD7
carotenoid cleavage dioxygenase 7
carotenoid cleavage dioxygenases 7
CCD7
MAX3
NCED7
-
-
-
-
ZmCCD7
CCD7
-
-
-
-
MAX3
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
9-cis-beta-carotene + O2 = 9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
9-cis-beta-carotene:O2 oxidoreductase (9',10'-cleaving)
Requires Fe2+. The enzyme participates in a pathway leading to biosynthesis of strigolactones, plant hormones involved in promotion of symbiotic associations known as arbuscular mycorrhiza.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(7E,7'E,9Z,9'E)-7',8'-dihydro-psi,psi-carotene + O2
zeta-apo-10'-carotenal + beta-ionone
-
-
-
?
(7E,7'E,9Z,9'E)-lycopene + O2
zeta-apo-10'-carotenal + beta-ionone
-
-
-
?
9'-cis-neurosporene + O2
zeta-apo-10'-carotenal + beta-ionone
low activity
-
-
?
9-cis-zeta-carotene + O2
9-cis-zeta-apo-10'-carotenal + beta-ionone
-
-
-
?
beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
isoform CCD1 prefers to cleave the 9, 10 position of beta-carotene
-
-
?
9-cis-beta-carotene + 02
9-cis-beta-apo-10'-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
AtCCD7 preferentially cleaves 9-cis-beta-carotene
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-lutein + O2
9-cis-3-hydroxy-epsilon-apo-10'-carotenal + 3-hydroxy-beta-ionone
-
-
-
?
9-cis-lutein + O2
9-cis-3-hydroxy-epsilon-apo-10'-carotenal + 3-hydroxy-beta-ionone
-
-
-
-
?
9-cis-lutein + O2
9-cis-3-hydroxy-epsilon-apo-10'-carotenal + ?
-
-
-
-
?
9-cis-zeaxanthin + O2
9-cis-3-hydroxy-beta-apo-10'-carotenal + 3-hydroxy-beta-ionone
-
-
-
?
9-cis-zeaxanthin + O2
9-cis-3-hydroxy-beta-apo-10'-carotenal + 3-hydroxy-beta-ionone
-
-
-
-
?
9-cis-zeaxanthin + O2
9-cis-3-hydroxy-beta-apo-10'-carotenal + ?
-
-
-
-
?
additional information
?
-
no substrate: lycopene, lutein, zeaxanthin, violaxanthin, or neoxanthin
-
-
?
additional information
?
-
substrate- and stereospecificity of Arabidopsis thaliana carotenoid cleavage dioxygenase 7, overview
-
-
?
additional information
?
-
AtCCD7 cleaves asymmetrically at the 9, 10, and 9', 10' bonds
-
-
?
additional information
?
-
enzyme CCD7 cleaves different 9-cis-carotenoids, yielding hydroxylated 9-cis-apo-10'-carotenals that may lead to hydroxylated carlactones, but show highest affinity for 9-cis-beta-carotene. The enzyme has a higher affinity to 9-cis-beta-carotene than to 9-cis-zeaxanthin, but converts the latter with higher rate. No detectable conversion of 9-cis-violaxanthin, all-trans-lutein, -zeaxanthin or -cryptoxanthin
-
-
?
additional information
?
-
enzyme substrate specificity, dynamic modeling, overview. No activity with the tri-cis-configured PDS or ZDS intermediates and products, i.e. 9,15-di-cis-phytofluene, 9,15,9'-tri-cis-zeta-carotene, 7,9,9'-tri-cis-neurosporene, and 7,9,9',7-tetra-cis-lycopene, as well as with non-canonical isomers of phytofluene (9-cis, 15-cis, all-trans). 9-cis-Lycopene is a poor substrate, and all-trans-lycopene is no substrate. AtCCD7 shows specificity for cleavage of the trans-configured C9-C10 double bond
-
-
?
additional information
?
-
-
the enzyme does not act on 9-cis-violaxanthin
-
-
-
additional information
?
-
-
substrate- and stereospecificity of Pisum sativum carotenoid cleavage dioxygenase 7, overview
-
-
?
additional information
?
-
-
enzyme CCD7 cleaves different 9-cis-carotenoids, yielding hydroxylated 9-cis-apo-10'-carotenals that may lead to hydroxylated carlactones, but show highest affinity for 9-cis-beta-carotene. The enzyme has a higher affinity to 9-cis-beta-carotene than to 9-cis-zeaxanthin, but converts the latter with higher rate. No detectable conversion of 9-cis-violaxanthin, all-trans-lutein, -zeaxanthin or -cryptoxanthin
-
-
?
additional information
?
-
recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
additional information
?
-
-
recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
additional information
?
-
recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
additional information
?
-
-
recombinant ZpCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-beta-carotene + O2
9-cis-10'-apo-beta-carotenal + beta-ionone
-
-
-
-
?
9-cis-zeaxanthin + O2
9-cis-3-hydroxy-beta-apo-10'-carotenal + 3-hydroxy-beta-ionone
-
-
-
?
9-cis-zeaxanthin + O2
9-cis-3-hydroxy-beta-apo-10'-carotenal + 3-hydroxy-beta-ionone
-
-
-
-
?
additional information
?
-
substrate- and stereospecificity of Arabidopsis thaliana carotenoid cleavage dioxygenase 7, overview
-
-
?
additional information
?
-
-
substrate- and stereospecificity of Pisum sativum carotenoid cleavage dioxygenase 7, overview
-
-
?
additional information
?
-
recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
additional information
?
-
-
recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
additional information
?
-
recombinant ZmCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
additional information
?
-
-
recombinant ZpCCD7 is able to efficiently catalyze metabolism of linear and cyclic carotenoids in Escherichia coli, and generates bionone by cleaving beta-carotene at the 9,10 (9',10') position. The recombinant enzyme in Escherichia coli catalyzes convertion of individual carotenoids including phytoene, lycopene, delta-carotene, ecarotene, beta-carotene, and zeaxanthin
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
methanol
addition of methanol to in vitro assays has a stimulatory effect on activity at concentrations up to 25%
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.0152
beta-carotene
pH 7.0, temperature not specified in the publication
0.0411
9-cis-beta-carotene
recombinant enzyme, pH not specified in the publication, 28°C
0.0596
9-cis-beta-carotene
-
recombinant enzyme, pH not specified in the publication, 28°C
0.1487
9-cis-zeaxanthin
recombinant enzyme, pH not specified in the publication, 28°C
0.626
9-cis-zeaxanthin
-
recombinant enzyme, pH not specified in the publication, 28°C
additional information
additional information
Michaelis-Menten kinetics
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
28
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pI VALUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
meristematic zone and the pericycle of the elongation zone of the roots
brenda
-
meristematic zone and the pericycle of the elongation zone of the roots
-
brenda
-
meristematic zone and the pericycle of the elongation zone of the roots
brenda
-
subterranean shoot named spider, moderate to low expression level of CCD8
brenda
additional information
CsCCD7 expression is not higher in the newly developed vascular tissue of axillary buds compared to the vascular tissue of the apical bud. Tissue expression analysis, overview
brenda
additional information
-
developmental expression of CCD7 in different tissues of the parasite, overview
brenda
additional information
CCD7 expression is highly responsive to phosphorus deficiency, especially in the meristematic zone and the pericycle of the elongation zone of maize roots. The crown root has the strongest ZmCCD7 expression in the meristematic zone under phosphorus limitation
brenda
additional information
-
CCD7 expression is highly responsive to phosphorus deficiency, especially in the meristematic zone and the pericycle of the elongation zone of maize roots. The crown root has the strongest ZmCCD7 expression in the meristematic zone under phosphorus limitation
brenda
additional information
-
CCD7 expression is highly responsive to phosphorus deficiency, especially in the meristematic zone and the pericycle of the elongation zone of maize roots. The crown root has the strongest ZmCCD7 expression in the meristematic zone under phosphorus limitation
-
brenda
additional information
-
CCD7 expression is highly responsive to phosphorus deficiency, especially in the meristematic zone and the pericycle of the elongation zone of maize roots
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
protein contains a probable chloroplast targeting sequence of 31 amino acids
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
evolution
malfunction
metabolism
biosynthesis of strigolactones requires the action of two CCD enzymes, CCD7 and CCD8 (EC 1.13.11.70), which act sequentially on 9-cis-beta-carotene, strigolactone biosynthesis pathway from all-trans-beta-carotene to ent-2'-epi-5-deoxystrigol
physiological function
additional information
evolution
occurrence of duplication in CCD4 genes that evolved into two new genes CCD7 and CCD8, EC 1.13.11.70. The site-specific profile and coefficient of type-I functional divergences reveals critical amino acid residues, leading to subgroup-specific functional evolution after their phylogenetic diversification
evolution
Zea mays ZmCCD7 and Zea mays subsp. parviglumis ZpCCD7 have the same coding sequence, indicating negative selection of the CCD7 gene over domestication from Zea mays subsp. parviglumis to Zea mays. ZmCCD7/ZpCCD7 encodes a carotenoid cleavage dioxygenase mediating strigolactone biosynthesis in maize and its ancestor
evolution
-
Zea mays ZmCCD7 and Zea mays subsp. parviglumis ZpCCD7 have the same coding sequence, indicating negative selection of the CCD7 gene over domestication from Zea mays subsp. parviglumis to Zea mays. ZmCCD7/ZpCCD7 encodes a carotenoid cleavage dioxygenase mediating strigolactone biosynthesis in maize and its ancestor
evolution
-
Zea mays ZmCCD7 and Zea mays subsp. parviglumis ZpCCD7 have the same coding sequence, indicating negative selection of the CCD7 gene over domestication from Zea mays subsp. parviglumis to Zea mays. ZmCCD7/ZpCCD7 encodes a carotenoid cleavage dioxygenase mediating strigolactone biosynthesis in maize and its ancestor
-
malfunction
-
tomato plants expressing a SlCCD7 antisense construct display greatly increased branching. A metabolomic screen is conducted. With the exception of a reduction of stem amino acid content in the transgenic lines, no major changes are observed. Targeted analysis of the same plants reveal significantly decreased levels of strigolactone. There are no significant changes in root carotenoids, indicating that relatively little substrate is required to produce the bioactive strigolactones. The germination rate of Orobanche ramosa seeds is reduced by up to 90% on application of extract from the SlCCD7 antisense lines, compared with the wild type. Upon mycorrhizal colonization, C13 cyclohexenone and C14 mycorradicin apocarotenoid levels are greatly reduced in the roots of the antisense lines, implicating SlCCD7 in their biosynthesis
malfunction
-
gene silencing of CCD7 in Phelipanche aegyptiaca by tobacco rattle virus system retards the parasite development on the host. Transient knockdown of PaCCD7 inhibits tubercle development and the infestation process in host plants. The number of parasite tubercles attached to the roots of host plants treated with TRV:PaCCD7, TRV:PaCCD8, or a mixture of TRV:PaCCD7 and TRV:PaCCD8 is significantly reduced by 95% as compared to control plants
malfunction
suppression of shoot branching in the Arabidopsis thaliana Col-0 ccd7 max3 mutant by transformation of ZmCCD7/ZpCCD7. Knockout or knockdown of these CCD7 results in numerous shoot branches by blocking or reducing strigolactone production
malfunction
-
suppression of shoot branching in the Arabidopsis thaliana Col-0 ccd7 max3 mutant by transformation of ZmCCD7/ZpCCD7. Knockout or knockdown of these CCD7 results in numerous shoot branches by blocking or reducing strigolactone production
malfunction
-
suppression of shoot branching in the Arabidopsis thaliana Col-0 ccd7 max3 mutant by transformation of ZmCCD7/ZpCCD7. Knockout or knockdown of these CCD7 results in numerous shoot branches by blocking or reducing strigolactone production
-
physiological function
coexpression of the enzyme, CCD7, and all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase CCD8, EC 1.13.11.70, in Escherichia coli results in production of 13-apo-beta-carotenone. The sequential cleavages of beta-carotene by CCD7 and CCD8 are likely the initial steps in the synthesis of a carotenoid-derived signaling molecule that is necessary for the regulation lateral branching
physiological function
loss-of-function mutants exhibit a significant decrease in petiole length and are highly branched. The axillary buds, which are typically delayed in growth in wild-type plants, grow out to produce leaves and inflorescences. The mutant plant have smaller rosette diameters due to a decrease in the lengths of petioles and leaf blades compared with wild-type plants. The phenotypes contribute to the bushy appearance of the mutants. The double mutant, additionally lacking 10'-apo-beta-carotenal 13,14-cleaving dioxygenase activity, EC 1.13.11.70, is phenotypically indistinguishable from either single mutant, indicating an interaction consistent with both genes functioning in the same pathway. Both classes of plants show a slight increase in inflorescence number compared with wild type
physiological function
biosynthesis of strigolactones requires the action of two CCD enzymes, CCD7 and CCD8 (EC 1.13.11.70), which act sequentially on 9-cis-beta-carotene
physiological function
CCD7 enzymes are highly stereospecific, cleaving only 9-cis-configured substrates, such as 9-cis-beta-carotene. The strigolactone biosynthetic enzyme AtCCD7 converts 9-cis-configured acyclic carotenes, such as 9-cis-zeta-carotene, 9'-cis-neurosporene, and 9-cis-lycopene, yielding 9-cis-configured products and indicating that AtCCD7, rather than AtCCD4, is the candidate for forming acyclic retrograde signals that are thought to derive from the cleavage of poly-cis-configured carotene desaturation intermediates
physiological function
-
important role of the strigolactone associated gene PaCCD7 in the parasite life cycle, and roles of CCD7 and CCD8 enzymes in the biosynthesis of strigolactones
physiological function
strigolactones are apocarotenoids generated via all-trans-beta-carotene isomerization, sequential oxidative cleavage of 9-cis-beta-carotene by two carotenoid cleavage dioxygenases (CCD7 and CCD8)
physiological function
-
strigolactones are apocarotenoids generated via all-trans-beta-carotene isomerization, sequential oxidative cleavage of 9-cis-beta-carotene by two carotenoid cleavage dioxygenases (CCD7 and CCD8)
physiological function
-
strigolactones are phytohormones synthesized from carotenoids via a stereospecific pathway involving the carotenoid cleavage dioxygenases 7 (CCD7) and 8. CCD7 cleaves 9-cis-beta-carotene to form a supposedly 9-cis-configured beta-apo-10'-carotenal
physiological function
strigolactones are phytohormones synthesized from carotenoids via a stereospecific pathway involving the carotenoid cleavage dioxygenases 7 (CCD7) and 8. CCD7 cleaves 9-cis-beta-carotene to form a supposedly 9-cis-configured beta-apo-10'-carotenal
physiological function
two carotenoid cleavage dioxygenases, CCD7 and CCD8, are involved in strigolactones biosynthesis. Involvement of the branching enzymes CCD7 and CCD8 in the control of bud sprouting and apical dominance. CsCCD7 and CsCCD8 expression show some overlapping, although they are not identical
physiological function
-
the enzyme plays an important role in the development of branches and inhibits the growth of axillary buds by up-regulating its downstream gene, BRC1
physiological function
-
strigolactones are apocarotenoids generated via all-trans-beta-carotene isomerization, sequential oxidative cleavage of 9-cis-beta-carotene by two carotenoid cleavage dioxygenases (CCD7 and CCD8)
-
additional information
in silico analysis, structure homology modeling, molecular modeling, dynamic simulation and structure comparisons of Arabidopsis thaliana carotenoid cleavage dioxygenases, overview
additional information
the biochemical basis of the shoot branching phenotype is not due to inhibition of enzyme CCD7, but of enzyme CCD8, EC 1.13.11.70
additional information
-
the biochemical basis of the shoot branching phenotype is not due to inhibition of enzyme CCD7, but of enzyme CCD8, EC 1.13.11.70
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). CCD7_ARATH
618
0
69453
Swiss-Prot
Chloroplast (Reliability: 3)
CCD7_ORYSJ
609
0
68188
Swiss-Prot
Chloroplast (Reliability: 4)
A0A2G9HWL6_9LAMI
658
0
73674
TrEMBL
Chloroplast (Reliability: 3)
A0A2G9FYF2_9LAMI
361
0
40081
TrEMBL
Chloroplast (Reliability: 2)
C4PJN3_MAIZE
619
0
68656
TrEMBL
other Location (Reliability: 3)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
CCD7M14
-
the chickpea mutant with G-to-A transition at nucleotide position 210 leading to stop codon at position 70 of the protein shows considerable resistance to broomrape (high resistance to both Phelipanche aegyptiaca and Orobanche crenata) and a strigolactone-deficiency phenotype, with a high number of short branches compared to wild type
additional information
additional information
enzyme is able to complement a CCD7/max3 mutation in Arabidopsis thaliana
additional information
a truncated enzyme protein of 587 amino acids lacking the N-terminal targeting sequence is also able to catalyze the 910 cleavage of beta-carotene. Coexpression of the enzyme, CCD7, and all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase CCD8, EC 1.13.11.70, in Escherichia coli results in production of 13-apo-beta-carotenone. The sequential cleavages of beta-carotene by CCD7 and CCD8 are likely the initial steps in the synthesis of a carotenoid-derived signaling molecule that is necessary for the regulation lateral branching
additional information
-
gene silencing of CCD7 in Phelipanche aegyptiaca by tobacco rattle virus system, parasitic PaCCD7 gene is silenced in Phelipanche aegyptiaca using a trans-silencing approach in Nicotiana benthamiana. Transient knockdown of PaCCD7 inhibits tubercle development and the infestation process in host plants
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANIC SOLVENT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE