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Disease on EC 1.13.11.2 - catechol 2,3-dioxygenase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acute Lung Injury
Etomidate attenuates hyperoxia-induced acute lung injury in mice by modulating the Nrf2/HO-1 signaling pathway.
Adrenal Hyperplasia, Congenital
Biochemical properties of cytochrome P-450 in relation to steroid oxygenation.
Alzheimer Disease
Effect of the herbal formulation Shen-Zhi-Ling on an APP/PS1 mouse model of Alzheimer's disease by modulating the biliverdin reductase/heme oxygenase 1 system.
Interaction of amyloid precursor proteins and heme oxygenase.
Kinetic isotope effects and synthetic strategies for deuterated carbon-11 and fluorine-18 labelled PET radiopharmaceuticals.
Anemia
Porphobilinogen oxygenase from human erythrocytes.
Anemia, Hemolytic, Congenital
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.
Arthritis
Berberis aristata Ameliorates Adjuvant-Induced Arthritis by Inhibition of NF-?B and Activating Nuclear Factor-E2-related Factor 2/hem Oxygenase (HO)-1 Signaling Pathway.
Arthritis, Rheumatoid
[The medical reason for the prescription of COX-2 selective cyclo oxygenase inhibitor rofecoxib for the treatment of rheumatoid arthritis. A post-marketing surveillance study from Austria]
Asthma
Advances in aspirin-exacerbated respiratory disease (AERD).
Atherosclerosis
?-carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice.
Naringenin and atherosclerosis: a review of literature.
[Change and correlation of heme oxygenase/carbon monoxide and nitricoxide synthase/nitrogen monoxide system in atherosclerotic progress of rabbits]
Brain Infarction
A lignocaine infusion worsens the leukoencephalopathy due to a carbon monoxide exposure in sheep.
Carcinogenesis
?-Carotene 9',10' Oxygenase Modulates the Anticancer Activity of Dietary Tomato or Lycopene on Prostate Carcinogenesis in the TRAMP Model.
Benzo(a)pyrene affects proliferation with reference to metabolic genes and ROS/HIF-1?/HO-1 signaling in A549 and MCF-7 cancer cells.
Endomembrane-Targeting Plasmodiophora brassicae Effectors Modulate PAMP Triggered Immune Responses in Plants.
Induction of the putative protective protein ferritin by infrared radiation: implications in skin repair.
Carcinosarcoma
Differential effects of Walker 256 carcinosarcoma cells growing subcutaneously, intramuscularly, or intraperitoneally on hepatic microsomal mixed-function oxygenase activity.
Cardiomegaly
Dexrazoxane does not protect against doxorubicin-induced damage in young rats.
Cardiomyopathies
The CO/HO system reverses inhibition of mitochondrial biogenesis and prevents murine doxorubicin cardiomyopathy.
Cardiovascular Diseases
Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases.
Haeme oxygenase signalling pathway: implications for cardiovascular disease.
Identification of Disease-Related 2-Oxoglutarate/Fe (II)-Dependent Oxygenase Based on Reduced Amino Acid Cluster Strategy.
Light-Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske-Type Oxygenase from Human Microbiota.
Chagas Disease
Haeme oxygenase activity protects the host against excessive cardiac inflammation during experimental Trypanosoma cruzi infection.
Cholestasis
BCNU-induced quantitative and qualitative changes in hepatic cytochrome P-450 can be correlated with cholestasis.
COVID-19
Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections.
Dehydration
Peniphenone and Penilactone Formation in Penicillium crustosum via 1,4-Michael Additions of ortho-Quinone Methide from Hydroxyclavatol to ?-Butyrolactones from Crustosic Acid.
Single-cell C(4) photosynthesis versus the dual-cell (Kranz) paradigm.
Diabetic Foot
The Presence of Oxygen in Wound Healing.
Diabetic Nephropathies
Ferroptosis Enhanced Diabetic Renal Tubular Injury via HIF-1?/HO-1 Pathway in db/db Mice.
PATHOBIOLOGY OF RENAL SPECIFIC OXIDOREDUCTASE/MYO-INOSITOL OXYGENASE IN DIABETIC NEPHROPATHY: ITS IMPLICATIONS IN TUBULO-INTERSTITIAL FIBROSIS.
Essential Hypertension
Association of a promoter variant of the haeme oxygenase-1 gene with hypertension in women.
Foot Ulcer
The Presence of Oxygen in Wound Healing.
Glioma
AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells.
Hemochromatosis
Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis.
Hemophilia A
Tolerance to FVIII: Role of the Immune Metabolic Enzymes Indoleamine 2,3 Dyoxigenase-1 and Heme Oxygenase-1.
Hyperalgesia
The Inhibitory Effects of Slow-Releasing Hydrogen Sulfide Donors in the Mechanical Allodynia, Grip Strength Deficits, and Depressive-Like Behaviors Associated with Chronic Osteoarthritis Pain.
Hypersensitivity
Advances in aspirin-exacerbated respiratory disease (AERD).
Hypertension
Cytochrome P450, the arachidonic acid cascade, and hypertension: new vistas for an old enzyme system.
Endothelial NO synthase as a source of NO and superoxide.
Hypertension, Portal
Effects of Nuclear Factor-E2-related factor 2/Heme Oxygenase 1 on splanchnic hemodynamics in experimental cirrhosis with portal hypertension.
Hypertension, Pulmonary
Impact of hydrogen sulfide on carbon monoxide/heme oxygenase pathway in the pathogenesis of hypoxic pulmonary hypertension.
[Impact of hydrogen sulfide donor on experimental pulmonary hypertension induced by high pulmonary flow and endogenous carbon monoxide/heme oxygenase pathway.]
[Interaction between endogenous nitric oxide and hydrogen sulfide in pathogenesis of hypoxic pulmonary hypertension]
[The regulation of carbon monoxide/heme oxygenase system by hydrogen sulfide in rats with hypoxic pulmonary hypertension]
[The role of endogenous carbon monoxide in vascular remodeling in hypoxic pulmonary hypertension].
Ileus
Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility.
Infections
Endomembrane-Targeting Plasmodiophora brassicae Effectors Modulate PAMP Triggered Immune Responses in Plants.
Enterovirus 71 induces neural cell apoptosis and autophagy through promoting ACOX1 downregulation and ROS generation.
Haeme oxygenase activity protects the host against excessive cardiac inflammation during experimental Trypanosoma cruzi infection.
Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections.
The Presence of Oxygen in Wound Healing.
Insulin Resistance
A? exacerbates ?-synuclein-induced neurotoxicity through impaired insulin signaling in ?-synuclein-overexpressed human SK-N-MC neuronal cells.
Ischemic Stroke
Andrographolide stimulates p38 mitogen-activated protein kinase-nuclear factor erythroid-2-related factor 2-heme oxygenase 1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats.
Keratoconus
Screening for Novel LOX and SOD1 Variants in Keratoconus Patients from Brazil.
Leukemia
12-Lipoxygenase from rat basophilic leukemia cells, an oxygenase with leukotriene A4-synthase activity.
Cytotoxicity of fatty acid oxygenase activation in rat basophilic leukemia cells.
Liver Cirrhosis, Biliary
Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis.
Liver Diseases
[Monooxigenase activity in liver diseases (study based on data of antipyrine metabolism)]
Lung Injury
Electroacupuncture Attenuates Limb Ischemia-Reperfusion-Induced Lung Injury Via p38 Mitogen-Activated Protein Kinase-Nuclear Factor Erythroid-2-Related Factor-2/Heme Oxygenase Pathway.
The effect of composition, size, and solubility on acute pulmonary injury in rats following exposure to Mexico city ambient particulate matter samples.
Lymphoma
Efficient cDNA cloning method using solid phase DNA probe.
Mesothelioma
Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells.
Metabolic Syndrome
Association of NOS3-c.894G>T transversion with susceptibility to metabolic syndrome in Azar-cohort population: A case-control study and in silico analysis of the SNP molecular effects.
Neoplasms
A SNP uncoupling Mina expression from the TGF? signaling pathway.
Antihyperglycemic potentials of a threatened plant, Helonias dioica: antioxidative stress responses and the signaling cascade.
Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.
Controlled exposure to diesel exhaust and traffic noise--Effects on oxidative stress and activation in mononuclear blood cells.
Cyclophosphamide-induced oncogenic transformation, chromosomal breakage, and sister chromatid exchange following microsomal activation.
Differential effects of Walker 256 carcinosarcoma cells growing subcutaneously, intramuscularly, or intraperitoneally on hepatic microsomal mixed-function oxygenase activity.
Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation.
Discovery of pyrazole derivatives as cellular active inhibitors of histone lysine specific demethylase 5B (KDM5B/JARID1B).
Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance.
Identification of Disease-Related 2-Oxoglutarate/Fe (II)-Dependent Oxygenase Based on Reduced Amino Acid Cluster Strategy.
No oxidative stress or DNA damage in peripheral blood mononuclear cells after exposure to particles from urban street air in overweight elderly.
Nrf2/HO-1 Axis Regulates the Angiogenesis of Gastric Cancer via Targeting VEGF.
Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells.
Progressive apoptosis in chorion laeve trophoblast cells of human fetal membrane tissues during in vitro incubation is suppressed by antioxidative reagents.
Transient Vasodilation in Mouse 4T1 Tumors after Intragastric and Intravenous Administration of Gold Nanoparticles.
Trisindoline synthesis and anticancer activity.
[Effect of hepatocarcinogenicity of estragole on the glucocorticoid-mediated induction of liver-specific enzymes and the activity of the transcription factors FOXA and HNF4 in the liver of mouse and rat]
[Effect of ionol on oxygenase level in proliferating animal tissues]
Neurodegenerative Diseases
Localization of NADPH cytochrome P450 oxidoreductase in rat brain by immunohistochemistry and in situ hybridization and a comparison with the distribution of neuronal NADPH-diaphorase staining.
Obesity
Molecular characterization and expression analysis of fat mass and obesity-associated gene in rabbit.
Osteoarthritis
The Inhibitory Effects of Slow-Releasing Hydrogen Sulfide Donors in the Mechanical Allodynia, Grip Strength Deficits, and Depressive-Like Behaviors Associated with Chronic Osteoarthritis Pain.
Ovarian Neoplasms
Apatinib, a Novel Tyrosine Kinase Inhibitor, Promotes ROS-Dependent Apoptosis and Autophagy via the Nrf2/HO-1 Pathway in Ovarian Cancer Cells.
SIRT5 Promotes Cisplatin Resistance in Ovarian Cancer by Suppressing DNA Damage in a ROS-Dependent Manner via Regulation of the Nrf2/HO-1 Pathway.
Pancreatic Neoplasms
Structure and assembly of the diiron cofactor in the heme-oxygenase-like domain of the N-nitrosourea-producing enzyme SznF.
Pneumonia
A SNP uncoupling Mina expression from the TGF? signaling pathway.
Lack of Transcription Factor p53 Exacerbates Elastase-Induced Emphysema in Mice.
Porphyria Cutanea Tarda
Porphobilinogen oxygenase from human erythrocytes.
Porphyria, Erythropoietic
Porphobilinogen oxygenase from human erythrocytes.
Porphyrias
Porphobilinogen excretion in chemical induced porphyria: reversal by induction of porphobilinogen oxygenase.
Porphobilinogen oxygenase from human erythrocytes.
Porphyrias, Hepatic
Porphobilinogen oxygenase from human erythrocytes.
Prostatic Neoplasms
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer.
Mitochondrial Beta-Carotene 9, 10 Oxygenase Modulates Prostate Cancer Growth via NF-kappaB Inhibition: a Lycopene-Independent Function.
Single Nucleotide Polymorphisms in ?-Carotene Oxygenase 1 are Associated with Plasma Lycopene Responses to a Tomato-Soy Juice Intervention in Men with Prostate Cancer.
Reperfusion Injury
Consequences of exercising on ischemia-reperfusion injury in type 2 diabetic Goto-Kakizaki rat hearts: role of the HO/NOS system.
Rhinitis, Allergic
Impact of Carbon Monoxide/Heme Oxygenase on Hydrogen Sulfide/Cystathionine-?-lyase Pathway in the Pathogenesis of Allergic Rhinitis in Guinea Pigs.
Sarcoma, Avian
A catechol 2,3-dioxygenase gene as a reporter.
Seizures, Febrile
Interaction between endogenous nitric oxide and carbon monoxide in the pathogenesis of recurrent febrile seizures.
Sepsis
Secreted lipoxygenase from Pseudomonas aeruginosa exhibits biomembrane oxygenase activity and induces hemolysis in human red blood cells.
Skin Diseases
Epidermal fatty acid oxygenases are activated in non-psoriatic dermatoses.
Starvation
Effect of carbon starvation on toluene degradation activity by toluene monooxygenase-expressing bacteria.
Subarachnoid Hemorrhage
Recombinant milk fat globule-EGF factor-8 reduces oxidative stress via integrin ?3/nuclear factor erythroid 2-related factor 2/heme oxygenase pathway in subarachnoid hemorrhage rats.
Superinfection
Efficient cDNA cloning method using solid phase DNA probe.
Thrombosis
First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.
The effect of composition, size, and solubility on acute pulmonary injury in rats following exposure to Mexico city ambient particulate matter samples.
Tuberculosis
A novel IS element, ISMpa1, in Mycobacterium avium subsp. paratuberculosis.
Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis.
Molecular characterization of the eis promoter of Mycobacterium tuberculosis.
Mycobacterium tuberculosis Rv3160c is a TetR-like transcriptional repressor that regulates expression of the putative oxygenase Rv3161c.
Pharmacokinetics of aldosterone in patients with Addison's disease: effect of rifampicin treatment on glucocorticoid and mineralocorticoid metabolism.