Reference on EC 1.11.1.24 - thioredoxin-dependent peroxiredoxin
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lee, T.H.; Kim, S.U.; Yu, S.L.; Kim, S.H.; Park do, S.; Moon, H.B.; Dho, S.H.; Kwon, K.S.; Kwon, H.J.; Han, Y.H.; Jeong, S.; Kang, S.W.; Shin, H.S.; Lee, K.K.; Rhee, S.G.; Yu, D.Y.
Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice
Blood
101
5033-5038
2003
Mus musculus
Jang, H.H.; Lee, K.O.; Chi, Y.H.; Jung, B.G.; Park, S.K.; Park, J.H.; Lee, J.R.; Lee, S.S.; Moon, J.C.; Yun, J.W.; Choi, Y.O.; Kim, W.Y.; Kang, J.S.; Cheong, G.W.; Yun, D.J.; Rhee, S.G.; Cho, M.J.; Lee, S.Y.
Two enzymes in one: Two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function
Cell
117
625-635
2004
Saccharomyces cerevisiae
Castro, H.; Budde, H.; Flohe, L.; Hofmann, B.; Lunsdorf, H.; Wissing, J.; Tomas, A.M.
Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum
Free Radic. Biol. Med.
33
1563-1574
2002
Leishmania infantum
Tsuji, N.; Kasuga-Aoki, H.; Isobe, T.; Yoshihara, S.
Cloning and characterisation of a peroxiredoxin from the swine roundworm Ascaris suum
Int. J. Parasitol.
30
125-128
2000
Ascaris suum (Q9NL98), Ascaris suum
Rhee, S.G.; Kang, S.W.; Chang, T.S.; Jeong, W.; Kim, K.
Peroxiredoxin, a novel family of peroxidases
IUBMB Life
52
35-41
2001
Homo sapiens, Rattus norvegicus
Baker, L.M.; Raudonikiene, A.; Hoffman, P.S.; Poole, L.B.
Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization
J. Bacteriol.
183
1961-1973
2001
Helicobacter pylori (P21762), Helicobacter pylori
Kang, S.W.; Chae, H.Z.; Seo, M.S.; Kim, K.; Baines, I.C.; Rhee, S.G.
Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha
J. Biol. Chem.
273
6297-6302
1998
Homo sapiens
Seo, M.S.; Kang, S.W.; Kim, K.; Baines, I.C.; Lee, T.H.; Rhee, S.G.
Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate
J. Biol. Chem.
275
20346-20354
2000
Homo sapiens
Choi, J.; Choi, S.; Choi, J.; Cha, M.K.; Kim, I.H.; Shin, W.
Crystal structure of Escherichia coli thiol peroxidase in the oxidized state: insights into intramolecular disulfide formation and substrate binding in atypical 2-Cys peroxiredoxins
J. Biol. Chem.
278
49478-49486
2003
Escherichia coli
Akerman, S.E.; Mller, S.
Peroxiredoxin-linked detoxification of hydroperoxides in Toxoplasma gondii
J. Biol. Chem.
280
564-570
2005
Toxoplasma gondii
Bernier-Villamor, L.; Navarro, E.; Sevilla, F.; Lazaro, J.J.
Cloning and characterization of a 2-Cys peroxiredoxin from Pisum sativum
J. Exp. Bot.
55
2191-2199
2004
Pisum sativum
Declercq, J.P.; Evrard, C.; Clippe, A.; Stricht, D.V.; Bernard, A.; Knoops, B.
Crystal structure of human peroxiredoxin 5, a novel type of mammalian peroxiredoxin at 1.5 A resolution
J. Mol. Biol.
311
751-759
2001
Homo sapiens (P30044), Homo sapiens
Evrard, C.; Capron, A.; Marchand, C.; Clippe, A.; Wattiez, R.; Soumillion, P.; Knoops, B.; Declercq, J.P.
Crystal structure of a dimeric oxidized form of human peroxiredoxin 5
J. Mol. Biol.
337
1079-1090
2004
Homo sapiens (P30044), Homo sapiens
Krnajski, Z.; Walter, R.D.; Muller, S.
Isolation and functional analysis of two thioredoxin peroxidases (peroxiredoxins) from Plasmodium falciparum
Mol. Biochem. Parasitol.
113
303-308
2001
Plasmodium falciparum (Q9GSV3), Plasmodium falciparum (Q9N699)
Akerman, S.E.; Mller, S.
2-Cys peroxiredoxin PfTrx-Px1 is involved in the antioxidant defence of Plasmodium falciparum
Mol. Biochem. Parasitol.
130
75-81
2003
Plasmodium falciparum
Cheong, N.E.; Choi, Y.O.; Lee, K.O.; Kim, W.Y.; Jung, B.G.; Chi, Y.H.; Jeong, J.S.; Kim, K.; Cho, M.J.; Lee, S.Y.
Molecular cloning, expression, and functional characterization of a 2Cys-peroxiredoxin in Chinese cabbage
Plant Mol. Biol.
40
825-834
1999
Brassica rapa (Q9SQJ4)
Konig, J.; Baier, M.; Horling, F.; Kahmann, U.; Harris, G.; Schurmann, P.; Dietz, K.J.
The plant-specific function of 2-Cys peroxiredoxin-mediated detoxification of peroxides in the redox-hierarchy of photosynthetic electron flux
Proc. Natl. Acad. Sci. USA
99
5738-5743
2002
Hordeum vulgare
Schroder, E.; Littlechild, J.A.; Lebedev, A.A.; Errington, N.; Vagin, A.A.; Isupov, M.N.
Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7 A resolution
Structure Fold. Des.
8
605-615
2000
Homo sapiens
Wen, L.; Huang, H.M.; Juang, R.H.; Lin, C.T.
Biochemical characterization of 1-Cys peroxiredoxin from Antrodia camphorata
Appl. Microbiol. Biotechnol.
73
1314-1322
2007
Taiwanofungus camphoratus (A1KZ88), Taiwanofungus camphoratus
Huang, J.K.; Ken, C.F.; Huang, H.M.; Lin, C.T.
Biochemical characterization of a novel 2-Cys peroxiredoxin from Antrodia camphorata
Appl. Microbiol. Biotechnol.
74
84-92
2007
Taiwanofungus camphoratus (A1KXU3), Taiwanofungus camphoratus
Nickel, C.; Trujillo, M.; Rahlfs, S.; Deponte, M.; Radi, R.; Becker, K.
Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite
Biol. Chem.
386
1129-1136
2005
Plasmodium falciparum
Sekiya, M.; Mulcahy, G.; Irwin, J.A.; Stack, C.M.; Donnelly, S.M.; Xu, W.; Collins, P.; Dalton, J.P.
Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica
FEBS Lett.
580
5016-5022
2006
Fasciola hepatica (P91883), Fasciola hepatica
Trujillo, M.; Mauri, P.; Benazzi, L.; Comini, M.; De Palma, A.; Flohe, L.; Radi, R.; Stehr, M.; Singh, M.; Ursini, F.; Jaeger, T.
The mycobacterial thioredoxin peroxidase can act as a one-cysteine peroxiredoxin
J. Biol. Chem.
281
20555-20566
2006
Mycobacterium tuberculosis
Conway, J.P.; Kinter, M.
Dual role of peroxiredoxin I in macrophage-derived foam cells
J. Biol. Chem.
281
27991-28001
2006
Mus musculus
Mizohata, E.; Sakai, H.; Fusatomi, E.; Terada, T.; Murayama, K.; Shirouzu, M.; Yokoyama, S.
Crystal structure of an archaeal peroxiredoxin from the aerobic hyperthermophilic crenarchaeon Aeropyrum pernix K1
J. Mol. Biol.
354
317-329
2005
Aeropyrum pernix
Molina-Lopez, J.; Jimenez, L.; Ochoa-Sanchez, A.; Landa, A.
Molecular cloning and characterization of a 2-Cys peroxiredoxin from Taenia solium
J. Parasitol.
92
796-802
2006
Taenia solium
Puetz, S.; Gelius-Dietrich, G.; Piotrowski, M.; Henze, K.
Rubrerythrin and peroxiredoxin: two novel putative peroxidases in the hydrogenosomes of the microaerophilic protozoon Trichomonas vaginalis
Mol. Biochem. Parasitol.
142
212-223
2005
Trichomonas vaginalis
Dombrecht, B.; Heusdens, C.; Beullens, S.; Verreth, C.; Mulkers, E.; Proost, P.; Vanderleyden, J.; Michiels, J.
Defence of Rhizobium etli bacteroids against oxidative stress involves a complexly regulated atypical 2-Cys peroxiredoxin
Mol. Microbiol.
55
1207-1221
2005
Rhizobium etli (O69777), Rhizobium etli
Boucher, I.W.; McMillan, P.J.; Gabrielsen, M.; Akerman, S.E.; Brannigan, J.A.; Schnick, C.; Brzozowski, A.M.; Wilkinson, A.J.; Mueller, S.
Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum
Mol. Microbiol.
61
948-959
2006
Plasmodium falciparum
Lamkemeyer, P.; Laxa, M.; Collin, V.; Li, W.; Finkemeier, I.; Schoettler, M.A.; Holtkamp, V.; Tognetti, V.B.; Issakidis-Bourguet, E.; Kandlbinder, A.; Weis, E.; Miginiac-Maslow, M.; Dietz, K.J.
Peroxiredoxin Q of Arabidopsis thaliana is attached to the thylakoids and functions in context of photosynthesis
Plant J.
45
968-981
2006
Arabidopsis thaliana
Vivancos, A.P.; Castillo, E.A.; Biteau, B.; Nicot, C.; Ayte, J.; Toledano, M.B.; Hidalgo, E.
A cysteine-sulfinic acid in peroxiredoxin regulates H2O2-sensing by the antioxidant Pap1 pathway
Proc. Natl. Acad. Sci. USA
102
8875-8880
2005
Schizosaccharomyces pombe
Barbey, C.; Rouhier, N.; Haouz, A.; Navaza, A.; Jacquot, J.P.
Overproduction, purification, crystallization and preliminary X-ray analysis of the peroxiredoxin domain of a larger natural hybrid protein from Thermotoga maritima
Acta Crystallogr. Sect. F
64
29-31
2008
Thermotoga maritima
Low, F.M.; Hampton, M.B.; Winterbourn, C.C.
Peroxiredoxin 2 and peroxide metabolism in the erythrocyte
Antioxid. Redox Signal.
10
1621-1630
2008
Homo sapiens
Zhang, H.; Go, Y.M.; Jones, D.P.
Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress
Arch. Biochem. Biophys.
465
119-126
2007
Homo sapiens
Trujillo, M.; Clippe, A.; Manta, B.; Ferrer-Sueta, G.; Smeets, A.; Declercq, J.P.; Knoops, B.; Radi, R.
Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation
Arch. Biochem. Biophys.
467
95-106
2007
Homo sapiens (P30044), Homo sapiens
Smeets, A.; Marchand, C.; Linard, D.; Knoops, B.; Declercq, J.P.
The crystal structures of oxidized forms of human peroxiredoxin 5 with an intramolecular disulfide bond confirm the proposed enzymatic mechanism for atypical 2-Cys peroxiredoxins
Arch. Biochem. Biophys.
477
98-104
2008
Homo sapiens (P30044), Homo sapiens
Yang, H.Y.; Jeong, D.K.; Kim, S.H.; Chung, K.J.; Cho, E.J.; Yang, U.; Lee, S.R.; Lee, T.H.
The role of peroxiredoxin III on late stage of proerythrocyte differentiation
Biochem. Biophys. Res. Commun.
359
1030-1036
2007
Mus musculus
Piacenza, L.; Peluffo, G.; Alvarez, M.N.; Kelly, J.M.; Wilkinson, S.R.; Radi, R.
Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite
Biochem. J.
410
359-368
2008
Trypanosoma cruzi
Tavender, T.J.; Sheppard, A.M.; Bulleid, N.J.
Peroxiredoxin IV is an endoplasmic reticulum-localized enzyme forming oligomeric complexes in human cells
Biochem. J.
411
191-199
2008
Homo sapiens (Q13162), Homo sapiens
Trotter, E.W.; Rand, J.D.; Vickerstaff, J.; Grant, C.M.
The yeast Tsa1 peroxiredoxin is a ribosome-associated antioxidant
Biochem. J.
412
73-80
2008
Saccharomyces cerevisiae
Park, S.Y.; Yu, X.; Ip, C.; Mohler, J.L.; Bogner, P.N.; Park, Y.M.
Peroxiredoxin 1 interacts with androgen receptor and enhances its transactivation
Cancer Res.
67
9294-9303
2007
Homo sapiens (Q06830)
Bacano Maningas, M.B.; Koyama, T.; Kondo, H.; Hirono, I.; Aoki, T.
A peroxiredoxin from kuruma shrimp, Marsupenaeus japonicus, inhibited by peptidoglycan
Dev. Comp. Immunol.
32
198-203
2008
Penaeus japonicus (A8R072), Penaeus japonicus
Aran, M.; Caporaletti, D.; Senn, A.M.; Tellez de Inon, M.T.; Girotti, M.R.; Llera, A.S.; Wolosiuk, R.A.
ATP-dependent modulation and autophosphorylation of rapeseed 2-Cys peroxiredoxin
FEBS J.
275
1450-1463
2008
Brassica napus (Q9FUC5)
Limauro, D.; Pedone, E.; Galdi, I.; Bartolucci, S.
Peroxiredoxins as cellular guardians in Sulfolobus solfataricus: characterization of Bcp1, Bcp3 and Bcp4
FEBS J.
275
2067-2077
2008
Saccharolobus solfataricus (Q97VL0), Saccharolobus solfataricus (Q97WG5), Saccharolobus solfataricus (Q97WP9), Saccharolobus solfataricus
Hansen, J.M.; Moriarty-Craige, S.; Jones, D.P.
Nuclear and cytoplasmic peroxiredoxin-1 differentially regulate NF-kappaB activities
Free Radic. Biol. Med.
43
282-288
2007
Homo sapiens
Loumaye, E.; Andersen, A.C.; Clippe, A.; Degand, H.; Dubuisson, M.; Zal, F.; Morsomme, P.; Rees, J.F.; Knoops, B.
Cloning and characterization of Arenicola marina peroxiredoxin 6, an annelid two-cysteine peroxiredoxin highly homologous to mammalian one-cysteine peroxiredoxins
Free Radic. Biol. Med.
45
482-493
2008
Arenicola marina (Q1AN22), Arenicola marina
Jonsson, A.; Teixeira, P.F.; Nordlund, S.
A novel peroxiredoxin activity is located within the C-terminal end of Rhodospirillum rubrum adenylyltransferase
J. Bacteriol.
190
434-437
2008
Rhodospirillum rubrum
Peskin, A.V.; Low, F.M.; Paton, L.N.; Maghzal, G.J.; Hampton, M.B.; Winterbourn, C.C.
The high reactivity of peroxiredoxin 2 with H(2)O(2) is not reflected in its reaction with other oxidants and thiol reagents
J. Biol. Chem.
282
11885-11892
2007
Homo sapiens (P32119), Homo sapiens
Lee, W.; Choi, K.S.; Riddell, J.; Ip, C.; Ghosh, D.; Park, J.H.; Park, Y.M.
Human peroxiredoxin 1 and 2 are not duplicate proteins: the unique presence of Cys83 in Prx1 underscores the structural and functional differences between Prx1 and Prx2
J. Biol. Chem.
282
22011-22022
2007
Homo sapiens (P32119), Homo sapiens (Q06830), Homo sapiens
Wakita, M.; Masuda, S.; Motohashi, K.; Hisabori, T.; Ohta, H.; Takamiya, K.
The significance of type II and PrxQ peroxiredoxins for antioxidative stress response in the purple bacterium Rhodobacter sphaeroides
J. Biol. Chem.
282
27792-27801
2007
Cereibacter sphaeroides
Matsumura, T.; Okamoto, K.; Iwahara, S.; Hori, H.; Takahashi, Y.; Nishino, T.; Abe, Y.
Dimer-oligomer interconversion of wild-type and mutant rat 2-Cys peroxiredoxin: disulfide formation at dimer-dimer interfaces is not essential for decamerization
J. Biol. Chem.
283
284-293
2008
Rattus norvegicus (Q63716)
Bae, J.Y.; Ahn, S.J.; Han, W.; Noh, D.Y.
Peroxiredoxin I and II inhibit H2O2-induced cell death in MCF-7 cell lines
J. Cell. Biochem.
101
1038-1045
2007
Homo sapiens (P30044), Homo sapiens (P32119), Homo sapiens (Q06830), Homo sapiens (Q13162)
Jara, M.; Vivancos, A.P.; Calvo, I.A.; Moldon, A.; Sanso, M.; Hidalgo, E.
The peroxiredoxin Tpx1 is essential as a H2O2 scavenger during aerobic growth in fission yeast
Mol. Biol. Cell
18
2288-2295
2007
Schizosaccharomyces pombe (O74887), Schizosaccharomyces pombe
Joensson, T.J.; Johnson, L.C.; Lowther, W.T.
Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace
Nature
451
98-101
2008
Homo sapiens (Q06830)
Barranco-Medina, S.; Krell, T.; Finkemeier, I.; Sevilla, F.; Lazaro, J.J.; Dietz, K.J.
Biochemical and molecular characterization of the mitochondrial peroxiredoxin PsPrxII F from Pisum sativum
Plant Physiol. Biochem.
45
729-739
2007
Pisum sativum (A0ZXY5), Pisum sativum
Parsonage, D.; Karplus, P.A.; Poole, L.B.
Substrate specificity and redox potential of AhpC, a bacterial peroxiredoxin
Proc. Natl. Acad. Sci. USA
105
8209-8214
2008
Salmonella enterica subsp. enterica serovar Typhimurium (P0A251), Salmonella enterica subsp. enterica serovar Typhimurium
Smeets, A.; Loumaye, E.; Clippe, A.; Rees, J.F.; Knoops, B.; Declercq, J.P.
The crystal structure of the C45S mutant of annelid Arenicola marina peroxiredoxin 6 supports its assignment to the mechanistically typical 2-Cys subfamily without any formation of toroid-shaped decamers
Protein Sci.
17
700-710
2008
Arenicola marina (Q1AN22)
Hong, S.; Kim, C.Y.; Lee, J.H.; Seong, G.J.
Immunohistochemical localization of 2-Cys peroxiredoxins in human ciliary body
Tissue Cell
39
365-368
2007
Homo sapiens, Homo sapiens (P32119), Homo sapiens (Q06830)
Manta, B.; Hugo, M.; Ortiz, C.; Ferrer-Sueta, G.; Trujillo, M.; Denicola, A.
The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2
Arch. Biochem. Biophys.
484
146-154
2009
Homo sapiens
Cox, A.G.; Peskin, A.V.; Paton, L.N.; Winterbourn, C.C.; Hampton, M.B.
Redox potential and peroxide reactivity of human peroxiredoxin 3
Biochemistry
48
6495-6501
2009
Homo sapiens
Hugo, M.; Turell, L.; Manta, B.; Botti, H.; Monteiro, G.; Netto, L.E.; Alvarez, B.; Radi, R.; Trujillo, M.
Thiol and sulfenic acid oxidation of AhpE, the one-cysteine peroxiredoxin from Mycobacterium tuberculosis: kinetics, acidity constants, and conformational dynamics
Biochemistry
48
9416-9426
2009
Mycobacterium tuberculosis
Manandhar, G.; Miranda-Vizuete, A.; Pedrajas, J.R.; Krause, W.J.; Zimmerman, S.; Sutovsky, M.; Sutovsky, P.
Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa
Biol. Reprod.
80
1168-1177
2009
Mus musculus, Sus scrofa
Donnelly, S.; Stack, C.M.; ONeill, S.M.; Sayed, A.A.; Williams, D.L.; Dalton, J.P.
Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages
FASEB J.
22
4022-4032
2008
Fasciola hepatica, Schistosoma mansoni
Pushpamali, W.A.; De Zoysa, M.; Kang, H.S.; Oh, C.H.; Whang, I.; Kim, S.J.; Lee, J.
Comparative study of two thioredoxin peroxidases from disk abalone (Haliotis discus discus): cloning, recombinant protein purification, characterization of antioxidant activities and expression analysis
Fish Shellfish Immunol.
24
294-307
2008
Haliotis discus discus (B1N693), Haliotis discus discus (B1N694)
Nikapitiya, C.; De Zoysa, M.; Whang, I.; Kim, C.G.; Lee, Y.H.; Kim, S.J.; Lee, J.
Molecular cloning, characterization and expression analysis of peroxiredoxin 6 from disk abalone Haliotis discus discus and the antioxidant activity of its recombinant protein
Fish Shellfish Immunol.
27
239-249
2009
Haliotis discus discus (B6RB12), Haliotis discus discus
Liau, Y.; Chen, Y.; Lin, C.; Huang, J.; Lin, C.
Characterisation of 2-Cys peroxiredoxin isozyme (Prx1) from Taiwanofungus camphorata (Niu-chang-chih): Expression and enzyme properties
Food Chem.
119
154-160
2010
Taiwanofungus camphoratus (A1KXR1)
Nakamura, T.; Kado, Y.; Yamaguchi, T.; Matsumura, H.; Ishikawa, K.; Inoue, T.
Crystal structure of peroxiredoxin from Aeropyrum pernix K1 complexed with its substrate, hydrogen peroxide
J. Biochem.
147
109-115
2009
Aeropyrum pernix (Q9Y9L0)
Trujillo, M.; Ferrer-Sueta, G.; Radi, R.
Kinetic studies on peroxynitrite reduction by peroxiredoxins
Methods Enzymol.
441
173-196
2008
Helicobacter pylori, Homo sapiens, Mycobacterium tuberculosis, Plasmodium falciparum, Saccharomyces cerevisiae, Trypanosoma brucei, Trypanosoma cruzi
Suttiprapa, S.; Loukas, A.; Laha, T.; Wongkham, S.; Kaewkes, S.; Gaze, S.; Brindley, P.J.; Sripa, B.
Characterization of the antioxidant enzyme, thioredoxin peroxidase, from the carcinogenic human liver fluke, Opisthorchis viverrini
Mol. Biochem. Parasitol.
160
116-122
2008
Opisthorchis viverrini (B4Y9T5), Opisthorchis viverrini
Cong, M.; Ni, D.; Song, L.; Wang, L.; Zhao, J.; Qiu, L.; Li, L.
Molecular cloning, characterization and mRNA expression of peroxiredoxin in Zhikong scallop Chlamys farreri
Mol. Biol. Rep.
36
1451-1459
2009
Azumapecten farreri (B3SP74), Azumapecten farreri
Tanaka, M.; Sakurai, T.; Yokoyama, N.; Inoue, N.; Kawazu, S.
Cloning and characterization of peroxiredoxin in Babesia bovis
Parasitol. Res.
105
1473-1477
2009
Babesia bovis
McNair, C.M.; Nisbet, A.J.; Billingsley, P.F.; Knox, D.P.
Molecular characterization, expression and localization of a peroxiredoxin from the sheep scab mite, Psoroptes ovis
Parasitology
136
453-460
2009
Psoroptes ovis (B6V3F6), Psoroptes ovis
Olahova, M.; Taylor, S.R.; Khazaipoul, S.; Wang, J.; Morgan, B.A.; Matsumoto, K.; Blackwell, T.K.; Veal, E.A.
A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance
Proc. Natl. Acad. Sci. USA
105
19839-19844
2008
Caenorhabditis elegans (Q21824), Caenorhabditis elegans (Q8IG31), Caenorhabditis elegans
Bhattacharyya, S.; Dutta, D.; Ghosh, A.K.; Das, A.K.
Cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of an atypical two-cysteine peroxiredoxin (SAOUHSC_01822) from Staphylococcus aureus NCTC 8325
Acta Crystallogr. Sect. F
65
1113-1115
2009
Staphylococcus aureus (Q2FXL3), Staphylococcus aureus, Staphylococcus aureus NCTC 8325 (Q2FXL3)
Hu, Z.; Lee, K.S.; Choo, Y.M.; Yoon, H.J.; Lee, S.M.; Lee, J.H.; Kim, D.H.; Sohn, H.D.; Jin, B.R.
Molecular cloning and characterization of 1-Cys and 2-Cys peroxiredoxins from the bumblebee Bombus ignitus
Comp. Biochem. Physiol. B
155
272-280
2010
Bombus ignitus (C3VVL4), Bombus ignitus (C3VVL6), Bombus ignitus
Loo, G.H.; Schuller, K.A.
Cloning and functional characterization of a peroxiredoxin 4 from yellowtail kingfish (Seriola lalandi)
Comp. Biochem. Physiol. B
156
244-253
2010
Seriola lalandi (B9USM4)
Sutton, D.L.; Loo, G.H.; Menz, R.I.; Schuller, K.A.
Cloning and functional characterization of a typical 2-Cys peroxiredoxin from southern bluefin tuna (Thunnus maccoyii)
Comp. Biochem. Physiol. B
156
97-106
2010
Thunnus maccoyii (A9QKS0), Thunnus maccoyii
Horta, B.B.; de Oliveira, M.A.; Discola, K.F.; Cussiol, J.R.; Netto, L.E.
Structural and biochemical characterization of peroxiredoxin Qbeta from Xylella fastidiosa: catalytic mechanism and high reactivity
J. Biol. Chem.
285
16051-16065
2010
Xylella fastidiosa (Q9PER7), Xylella fastidiosa
Parsonage, D.; Desrosiers, D.C.; Hazlett, K.R.; Sun, Y.; Nelson, K.J.; Cox, D.L.; Radolf, J.D.; Poole, L.B.
Broad specificity AhpC-like peroxiredoxin and its thioredoxin reductant in the sparse antioxidant defense system of Treponema pallidum
Proc. Natl. Acad. Sci. USA
107
6240-6245
2010
Treponema pallidum (O83522), Treponema pallidum
DAmbrosio, K.; Limauro, D.; Pedone, E.; Galdi, I.; Pedone, C.; Bartolucci, S.; De Simone, G.
Insights into the catalytic mechanism of the Bcp family: Functional and structural analysis of Bcp1 from Sulfolobus solfataricus
Proteins Struct. Funct. Bioinform.
76
995-1006
2009
Saccharolobus solfataricus (Q97WP9)
Kashima, Y.; Ishikawa, K.
Alkyl hydroperoxide reductase dependent on thioredoxin-like protein from Pyrococcus horikoshii
J. Biochem.
134
25-29
2003
Pyrococcus horikoshii (O58966), Pyrococcus horikoshii
Loumaye, E.; Ferrer-Sueta, G.; Alvarez, B.; Rees, J.F.; Clippe, A.; Knoops, B.; Radi, R.; Trujillo, M.
Kinetic studies of peroxiredoxin 6 from Arenicola marina: rapid oxidation by hydrogen peroxide and peroxynitrite but lack of reduction by hydrogen sulfide
Arch. Biochem. Biophys.
514
1-7
2011
Arenicola marina (Q1AN22), Arenicola marina
Park, J.W.; Piszczek, G.; Rhee, S.G.; Chock, P.B.
Glutathionylation of peroxiredoxin I induces decamer to dimers dissociation with concomitant loss of chaperone activity
Biochemistry
50
3204-3210
2011
Homo sapiens
Limauro, D.; D'Ambrosio, K.; Langella, E.; de Simone, G.; Galdi, I.; Pedone, C.; Pedone, E.; Bartolucci, S.
Exploring the catalytic mechanism of the first dimeric Bcp: Functional, structural and docking analyses of Bcp4 from Sulfolobus solfataricus
Biochimie
92
1435-1444
2010
Saccharolobus solfataricus (Q97VL0), Saccharolobus solfataricus P2 (Q97VL0)
Qiu, W.; Dong, A.; Pizarro, J.C.; Botchkarsev, A.; Min, J.; Wernimont, A.K.; Hills, T.; Hui, R.; Artz, J.D.
Crystal structures from the Plasmodium peroxiredoxins: new insights into oligomerization and product binding
BMC Struct. Biol.
12
002
2012
Plasmodium vivax, Plasmodium yoelii (Q7RSE5), Plasmodium vivax Sal-1
Chen, X.W.; Kang, L.H.; Ding, D.; Liu, Q.; Wang, J.X.; Kang, C.J.
Characterization of a 2-Cys peroxiredoxin IV in Marsupenaeus japonicus (kuruma shrimp) and its role in the anti-viral immunity
Fish Shellfish Immunol.
35
1848-1857
2013
Penaeus japonicus (A8R072), Penaeus japonicus
Ikeda, Y.; Nakano, M.; Ihara, H.; Ito, R.; Taniguchi, N.; Fujii, J.
Different consequences of reactions with hydrogen peroxide and t-butyl hydroperoxide in the hyperoxidative inactivation of rat peroxiredoxin-4
J. Biochem.
149
443-453
2011
Rattus norvegicus (Q9Z0V5)
Bang, Y.J.; Oh, M.H.; Choi, S.H.
Distinct characteristics of two 2-Cys peroxiredoxins of Vibrio vulnificus suggesting differential roles in detoxifying oxidative stress
J. Biol. Chem.
287
42516-42524
2012
Vibrio vulnificus (A0A087JKY6), Vibrio vulnificus (A0A1W6MAW2), Vibrio vulnificus MO6-24/O (A0A087JKY6), Vibrio vulnificus MO6-24/O (A0A1W6MAW2)
Kim, S.Y.; Jung, Y.J.; Shin, M.R.; Park, J.H.; Nawkar, G.M.; Maibam, P.; Lee, E.S.; Kim, K.S.; Paeng, S.K.; Kim, W.Y.; Lee, K.O.; Yun, D.J.; Kang, C.H.; Lee, S.Y.
Molecular and functional properties of three different peroxiredoxin isotypes in Chinese cabbage
Mol. Cells
33
27-33
2012
Brassica napus (Q8GZT7), Brassica rapa subsp. oleifera (Q9SQJ4), Brassica rapa subsp. pekinensis (Q9XF72), Brassica rapa subsp. pekinensis
Nakamura, T.; Matsumura, H.; Inoue, T.; Kai, Y.; Uegaki, K.; Hagihara, Y.; Ataka, M.; Ishikawa, K.
Crystallization and preliminary X-ray diffraction analysis of thioredoxin peroxidase from the aerobic hyperthermophilic archaeon Aeropyrum pernix K1
Acta Crystallogr. Sect. F
61
323-325
2005
Aeropyrum pernix (Q9Y9L0), Aeropyrum pernix DSM 11879 (Q9Y9L0)
Jeon S.J.; Ishikawa, K.
Characterization of novel hexadecameric thioredoxin peroxidase from Aeropyrum pernix K1
J. Biol. Chem.
278
24174-24180
2003
Aeropyrum pernix (Q9Y9L0), Aeropyrum pernix, Aeropyrum pernix DSM 11879 (Q9Y9L0)
Nakamura, T.; Yamamoto, T.; Abe, M.; Matsumura, H.; Hagihara, Y.; Goto, T.; Yamaguchi, T.; Inoue, T.
Oxidation of archaeal peroxiredoxin involves a hypervalent sulfur intermediate
Proc. Natl. Acad. Sci. USA
105
6238-6242
2008
Aeropyrum pernix (Q9Y9L0), Aeropyrum pernix DSM 11879 (Q9Y9L0)
Kawakami, R.; Sakuraba, H.; Kamohara, S.; Goda, S.; Kawarabayasi, Y.; Ohshima, T.
Oxidative stress response in an anaerobic hyperthermophilic archaeon Presence of a functional peroxiredoxin in Pyrococcus horikoshii
J. Biochem.
136
541-547
2004
Pyrococcus horikoshii (O58966), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (O58966)
Anusevicius, A.; Miseviciene, L.; Sarlauskas, J.; Rouhier, N.; Jacquot, J.; Cenas, N.
Quinone- and nitroreductase reactions of Thermotoga maritima peroxiredoxin-nitroreductase hybrid enzyme
Arch. Biochem. Biophys.
528
50-56
2012
Thermotoga maritima (Q9WZR4), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9WZR4)
Lakhal, R.; Auria, R.; Davidson, S.; Ollivier, B.; Durand, M.; Dolla, A.; Hamdi, M.; Combet-Blanc, Y.
Oxygen uptake rates in the hyperthermophilic anaerobe Thermotoga maritima grown in a bioreactor under controlled oxygen exposure Clues to its defence strategy against oxidative stress
Arch. Microbiol.
193
429-438
2011
Thermotoga maritima (Q9WZR4), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9WZR4)
Kong, W.; Shiota, S.; Shi, Y.; Nakayama, H.; Nakayama, K.
A novel peroxiredoxin of the plant Sedum lineare is a homologue of Escherichia coli bacterioferritin co-migratory protein Bcp
Biochem. J.
351
107-114
2000
Sedum lineare (Q9MB35), Sedum lineare
Perez-Perez, M.E.; Mata-Cabana, A.; Sanchez-Riego, A.M.; Lindahl, M.; Florencio, F.J.
A comprehensive analysis of the peroxiredoxin reduction system in the cyanobacterium Synechocystis sp. strain PCC 6803 reveals that all five peroxiredoxins are thioredoxin dependent
J. Bacteriol.
191
7477-7489
2009
Synechocystis sp. PCC 6803 (P72697), Synechocystis sp. PCC 6803 (P72719), Synechocystis sp. PCC 6803 (P73263), Synechocystis sp. PCC 6803 (P73728), Synechocystis sp. PCC 6803 (Q55624)
Jeong, W.; Cha, M.K.; Kim, I.H.
Thioredoxin-dependent hydroperoxide peroxidase activity of bacterioferritin comigratory protein (BCP) as a new member of the thiol-specific antioxidant protein (TSA)/alkyl hydroperoxide peroxidase C (AhpC) family
J. Biol. Chem.
275
2924-2930
2000
Escherichia coli (P0AE52), Escherichia coli, Escherichia coli K12 (P0AE52)
Rouhier, N.; Gelhaye, E.; Jacquot, J.P.
Glutaredoxin-dependent peroxiredoxin from poplar protein-protein interaction and catalytic mechanism
J. Biol. Chem.
277
13609-13614
2002
Populus trichocarpa (A9PCL4)
Cao, Y.; Yang, Q.; Tu, X.H.; Li, S.G.; Liu, S.
Molecular characterization of a typical 2-Cys thioredoxin peroxidase from the Asiatic rice borer Chilo suppressalis and its role in oxidative stress
Arch. Insect Biochem. Physiol.
99
e21476
2018
Chilo suppressalis (A0A2S0RQP8), Chilo suppressalis
Petrenko, V.A.; Pakharukova, M.Y.; Kovner, A.V.; Lvova, M.N.; Lyakhovich, V.V.; Mordvinov, V.A.
Secretion of thioredoxin peroxidase protein of cat liver fluke Opisthorchis felineus during modeling of experimental Opisthorchiasis
Bull. Exp. Biol. Med.
162
773-776
2017
Opisthorchis felineus
Luo, Y.; Wu, Y.; Munyampundu, J.
Role of alkyl hydroperoxide reductase subunit C (AhpC) as a peroxiredoxin in Leptospira interrogans against oxidative stress
Chin. J. Microbiol. Immunol.
38
193-198
2018
Leptospira interrogans
-
Nusai, K.; Doungdee, P.; Rungrotmongkol, T.
Study of drug likeness of praziquantel derivatives for the inhibition of thioredoxin peroxidase and aspartic protease in Opisthorchis viverrini by molecular docking method
Curr. Appl. Sci. Technol.
17
87-102
2017
Opisthorchis viverrini (B4Y9T5)
-
Jiang, G.; Yang, J.; Li, X.; Cao, Y.; Liu, X.; Ling, J.; Wang, H.; Zhong, Z.; Zhu2, J.
Alkyl hydroperoxide reductase is important for oxidative stress resistance and symbiosis in Azorhizobium caulinodans
FEMS Microbiol. Lett.
366
fnz014
2019
Azorhizobium caulinodans (A8HQP9), Azorhizobium caulinodans, Azorhizobium caulinodans ORS 571 (A8HQP9)
Zhang, H.; Wang, Z.; Huang, J.; Cao, J.; Zhou, Y.; Zhou, J.
A novel thioredoxin-dependent peroxiredoxin (TPx-Q) plays an important role in defense against oxidative stress and is a possible drug target in Babesia microti
Front. Vet. Sci.
7
76
2020
Babesia microti
Linder, R.; Greco, J.; Seidl, F.; Matsui, T.; Ehrenreich, I.
The stress-inducible peroxidase TSA2 underlies a conditionally beneficial chromosomal duplication in Saccharomyces cerevisiae
G3 (Bethesda)
7
3177-3184
2017
Saccharomyces cerevisiae (Q04120), Saccharomyces cerevisiae
Li, Y.; Sun, Y.; Gu, X.; Xie, Y.; Lai, W.; Jing, B.; Peng, X.; Yang, G.
Prokaryotic expression and serodiagnostic potential of glyceraldehyde-3-phosphate dehydrogenase and thioredoxin peroxidase from Baylisascaris schroederi
Genes (Basel)
8
293
2017
Baylisascaris schroederi
Wang, H.; Zhang, C.S.; Fang, B.B.; Li, Z.D.; Li, L.; Bi, X.J.; Li, W.D.; Zhang, N.; Lin, R.Y.; Wen, H.
Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway
Parasit. Vectors
12
542
2019
Echinococcus granulosus (Q8T6C4), Echinococcus granulosus
Mastud, P.; Patankar, S.
An ambiguous N-terminus drives the dual targeting of an antioxidant protein Thioredoxin peroxidase (TgTPx1/2) to endosymbiotic organelles in Toxoplasma gondii
PeerJ
7
e7215
2019
Toxoplasma gondii, Toxoplasma gondii RH
Liao, J.; Wang, K.; Yao, W.; Yi, X.; Yan, H.; Chen, M.; Lan, X.
Cloning, expression and antioxidant activity of a thioredoxin peroxidase from Branchiostoma belcheri tsingtaunese
PLoS ONE
12
e0175162
2017
Branchiostoma belcheri tsingtauense (Q5XUI0), Branchiostoma belcheri tsingtauense
Su, T.; Si, M.; Zhao, Y.; Liu, Y.; Yao, S.; Che, C.; Chen, C.
A thioredoxin-dependent peroxiredoxin Q from Corynebacterium glutamicum plays an important role in defense against oxidative stress
PLoS ONE
13
e0192674
2018
Corynebacterium glutamicum (Q8NMS6), Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032 (Q8NMS6)
Liu, Y.; Lu, F.; Guo, G.; Feng, D.; Zhang, B.; Gao, W.; Bi, R.
Crystallization and preliminary crystallographic analysis of thioredoxin-dependent thiol peroxidase (SF2523) from Shigella flexneri 2a str. 301
Prog. Biochem. Biophys.
44
253-258
2017
Shigella flexneri (P0AE55)
-
Liu, Y.; Yang, Y.; Xu, J.; Dong, X.; Gu, X.; Xie, Y.; Lai, W.; Jing, B.; Peng, X.; Yang, G.
Expression and serodiagnostic potential of antigen B and thioredoxin peroxidase from Taenia multiceps
Vet. Parasitol.
272
58-63
2019
Taenia multiceps (E9P5B2), Taenia multiceps
Liu, W.; Liu, A.; Gao, H.; Wang, Q.; Wang, L.; Warkentin, E.; Rao, Z.; Michel, H.; Peng, G.
Structural properties of the peroxiredoxin AhpC2 from the hyperthermophilic eubacterium Aquifex aeolicus
Biochim. Biophys. Acta
1862
2797-2805
2018
Aquifex aeolicus (O67024), Aquifex aeolicus
Chong, S.M.S.; Kamariah, N.; Grueber, G.
Residues of helix alpha2 are critical for catalytic efficiency of mycobacterial alkylhydroperoxide reductase subunit C
FEBS Lett.
594
2829-2839
2020
Mycobacterium tuberculosis variant bovis
Jin, Q.W.; Zhang, N.Z.; Li, W.H.; Qin, H.T.; Liu, Y.J.; Ohiolei, J.A.; Niu, D.Y.; Yan, H.B.; Li, L.; Jia, W.Z.; Song, M.X.; Fu, B.Q.
Trichinella spiralis thioredoxin peroxidase 2 regulates protective th2 immune response in mice by directly inducing alternatively activated macrophages
Front. Immunol.
11
2015
2020
Trichinella spiralis, Trichinella spiralis ISS534
Lian, F.M.; Jiang, Y.L.; Yang, W.; Yang, X.
Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 mimics a conformational intermediate during the catalytic cycle
Int. J. Biol. Macromol.
161
1055-1060
2020
Saccharomyces cerevisiae (P38013)
Adriani, P.P.; de Paiva, F.C.R.; de Oliveira, G.S.; Leite, A.C.; Sanches, A.S.; Lopes, A.R.; Dias, M.V.B.; Chambergo, F.S.
Structural and functional characterization of the glutathione peroxidase-like thioredoxin peroxidase from the fungus Trichoderma reesei
Int. J. Biol. Macromol.
167
93-100
2021
Trichoderma reesei (G0RHF8), Trichoderma reesei, Trichoderma reesei QM6a (G0RHF8)
Guo, X.; Zhang, J.; Li, R.; Li, H.; He, X.; Wang, S.; Wang, Z.; Harandi, M.F.; Hu, J.; Zheng, Y.
Molecular cloning and functional characterization of a thioredoxin peroxidase gene in Echinococcus multilocularis
Mol. Biochem. Parasitol.
245
111408
2021
Echinococcus multilocularis (Q86M52), Echinococcus multilocularis
html completed
