Information on EC 1.1.99.40 - (R)-2-hydroxyglutarate-pyruvate transhydrogenase

for references in articles please use BRENDA:EC1.1.99.40
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EC Tree
IUBMB Comments
The enzyme, characterized in the yeast Saccharomyces cerevisiae, also functions as EC 1.1.2.4, D-lactate dehydrogenase (cytochrome), and is active with oxaloacetate as electron acceptor forming (R)-malate.
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The enzyme appears in viruses and cellular organisms
Synonyms
D-2-hydroxyglutarate-pyruvate transhydrogenase, DLD3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-2-hydroxyglutarate + pyruvate = 2-oxoglutarate + (R)-lactate
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PATHWAY SOURCE
PATHWAYS
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