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Information on EC 1.1.5.10 - D-2-hydroxyacid dehydrogenase (quinone)

for references in articles please use BRENDA:EC1.1.5.10
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IUBMB Comments
The enzyme from mammalian kidney contains one mole of FAD per mole of enzyme.(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
(R)-2-hydroxy acid dehydrogenase, (R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase, D-lactate dehydrogenase, DLD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol
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