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The enzyme appears in viruses and cellular organisms
Synonyms
L-2-hydroxyphytanic acid oxidase, more
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L-2-hydroxyphytanic acid oxidase
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L-2-hydroxyphytanate + O2 = 2-oxophytanate + H2O2
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L-2-hydroxyphytanate:oxygen 2-oxidoreductase
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L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
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Substrates: -
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L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
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Substrates: deficiency in patients with Zellweger syndrome, which lack morphologically distinguishable peroxisomes
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L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
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Substrates: -
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L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
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Substrates: deficiency in patients with Zellweger syndrome, which lack morphologically distinguishable peroxisomes
Products: -
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L-2-hydroxyphytanate + O2
2-oxophytanate + H2O2
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Substrates: -
Products: -
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L-2-Hydroxyisocaproate
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0.15
L-2-Hydroxyphytanate
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7 - 9.5
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pH 7.0: about 45% of maximal activity, pH 9.5: about 80% of maximal activity
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brenda
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brenda
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cortex
brenda
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weak activity in medulla
brenda
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no activity in the medulla
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brenda
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no activity
brenda
additional information
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no activity in brain, cerebellum, skeletal muscle, heart or jejunal mucosa
brenda
additional information
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no activity in brain, cerebellum, skeletal muscle, heart or jejunal mucosa
brenda
additional information
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no activity in spleen and lung
brenda
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brenda
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brenda
Highest Expressing Human Cell Lines
Cell Line Links
Gene Links
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Vamecq, J.; Draye, J.P.
The enzymatic and mass spectrometric identification of 2-oxophytanic acid, a product of the peroxisomal oxidation of l-2-hydroxyphytanic acid
Biomed. Environ. Mass Spectrom.
15
345-351
1988
Rattus norvegicus
brenda
Draye, J.P.; van Hoof, F.; de Hoffmann, E.; Vamecq, J.
Peroxisomal oxidation of L-2-hydroxyphytanic acid in rat kidney cortex
Eur. J. Biochem.
167
573-578
1987
Rattus norvegicus
brenda
Wanders, R.J.A.; van Roermund, C.W.T.; Schor, D.S.M.; ten Brink, H.J.; Jakobs, C.
2-Hydroxyphytanic acid oxidase activity in rat and human liver and its deficiency in the Zellweger syndrome
Biochim. Biophys. Acta
1227
177-182
1994
Homo sapiens, Rattus norvegicus
brenda
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