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Information on EC 1.1.3.23 - thiamine oxidase

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EC Tree
     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.23 thiamine oxidase
IUBMB Comments
A flavoprotein (FAD). The product differs from thiamine in replacement of -CH2.CH2.OH by -CH2.COOH; the two-step oxidation proceeds without the release of the intermediate aldehyde from the enzyme.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
thiamin dehydrogenase, thiamin oxidase, thiamin:oxygen 5-oxidoreductase, thiamine dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
thiamine + 2 O2 + H2O = thiamine acetic acid + 2 H2O2
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PATHWAY SOURCE
PATHWAYS
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