Information on EC 188.8.131.52 - thiamine oxidasefor references in articles please use BRENDA:EC184.108.40.206
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A flavoprotein (FAD). The product differs from thiamine in replacement of -CH2.CH2.OH by -CH2.COOH; the two-step oxidation proceeds without the release of the intermediate aldehyde from the enzyme.
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The enzyme appears in viruses and cellular organisms
thiamin dehydrogenase, thiamin oxidase, thiamin:oxygen 5-oxidoreductase, thiamine dehydrogenase,
thiamine + 2 O2 + H2O = thiamine acetic acid + 2 H2O2
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