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BRENDA support

Information on EC 1.1.1.87 - homoisocitrate dehydrogenase

for references in articles please use BRENDA:EC1.1.1.87

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IUBMB Comments

Forms part of the lysine biosynthesis pathway in fungi .

The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

Synonyms
lys12, homoisocitrate dehydrogenase, tk0280, schicdh, homoisocitric dehydrogenase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
coenzyme B biosynthesis, L-lysine biosynthesis IV, L-lysine biosynthesis V