Reference on EC 1.1.1.428 - 4-methylthio 2-oxobutanoate reductase (NADH)

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Hilbert, B.J.; Morris, B.L.; Ellis, K.C.; Paulsen, J.L.; Schiffer, C.A.; Grossman, S.R.; Royer, W.E.

Structure-guided design of a high affinity inhibitor to human CtBP

ACS Chem. Biol.

1118-1127

2015

Homo sapiens

Achouri, Y.; Noel, G.; Van Schaftingen, E.

2-Keto-4-methylthiobutyrate, an intermediate in the methionine salvage pathway, is a good substrate for CtBP1

Biochem. Biophys. Res. Commun.

352

903-906

2007

Homo sapiens

Korwar, S.; Morris, B.; Parikh, H.; Coover, R.; Doughty, T.; Love, I.; Hilbert, B.; Royer, W.J.; Kellogg, G.; Grossman, S.; Ellis, K.

Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal binding protein (CtBP)

Bioorg. Med. Chem.

2707-2715

2016

Homo sapiens

Hilbert, B.J.; Grossman, S.R.; Schiffer, C.A.; Royer, W.E.

Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design

FEBS Lett.

588

1743-1748

2014

Homo sapiens (P56545), Homo sapiens (Q13363), Homo sapiens

Kumar, V.; Carlson, J.; Ohgi, K.; Edwards, T.; Rose, D.; Escalante, C.; Rosenfeld, M.; Aggarwal, A.

Transcription corepressor CtBP is an NAD+-regulated dehydrogenase

Mol. Cell.

857-869

2002

Homo sapiens