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Information on EC 1.1.1.421 - D-apionate oxidoisomerase

for references in articles please use BRENDA:EC1.1.1.421

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IUBMB Comments

The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. The reaction involves migration of a hydroxymethyl group from position 3 to position 2 and oxidation of the 3-hydroxyl group. Stereospecificity of the product, 3-oxoisoapionate, has not been determined.

The enzyme appears in viruses and cellular organisms

Synonyms
d-apionate oxidoisomerase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-apionate + NAD+ = 3-oxo-D-isoapionate + NADH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
D-apionate degradation I (xylose isomerase family decarboxylase), D-apionate degradation II (RLP decarboxylase), D-apionate degradation III (RLP transcarboxylase/hydrolase)
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