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Information on EC 1.1.1.421 - D-apionate oxidoisomerase

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IUBMB Comments
The enzyme, characterized from several bacterial species, participates in the degradation of D-apionate. The reaction involves migration of a hydroxymethyl group from position 3 to position 2 and oxidation of the 3-hydroxyl group. Stereospecificity of the product, 3-oxoisoapionate, has not been determined.
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The enzyme appears in viruses and cellular organisms
Synonyms
apnO, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-apionate + NAD+ = 3-oxo-D-isoapionate + NADH + H+
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PATHWAY SOURCE
PATHWAYS
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