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Information on EC 1.1.1.418 - plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

for references in articles please use BRENDA:EC1.1.1.418
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IUBMB Comments
The enzyme, found in plants, catalyses multiple reactions during plant sterol biosynthesis. Unlike the fungal/animal enzyme EC 1.1.1.170, 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating), the plant enzyme is specific for NAD+.
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The enzyme appears in viruses and cellular organisms
Synonyms
3beta-HSD/D1, 3beta-HSD/D2, 3beta-hydroxysteroid dehydrogenase/C-4 decarboxylase, 3beta-hydroxysteroid dehydrogenases/C-4 decarboxylase, 3beta-hydroxysteroid-dehydrogenase/C4-decarboxylase, 3betaHSD/D, 3betaHSD/D1, 3betaHSD/D2, 4alpha-carboxysterol-C3-dehydrogenase/C4-decarboxylase, 4alpha-CD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 3beta-hydroxysteroid-4alpha-carboxylate + NAD+ = a 3-oxosteroid + CO2 + NADH
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