Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

No. of entries

Information on EC 1.1.1.40 - malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

for references in articles please use BRENDA:EC1.1.1.40

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The enzyme catalyses the oxidative decarboxylation of (S)-malate in the presence of NADP+ and divalent metal ions, and the decarboxylation of oxaloacetate. cf. EC 1.1.1.38, malate dehydrogenase (oxaloacetate-decarboxylating), and EC 1.1.1.39, malate dehydrogenase (decarboxylating).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes

Synonyms
nadp-me, nadp-malate dehydrogenase, nadp-malic enzyme, nadp-mdh, nadp-dependent malic enzyme, nadp-dependent malate dehydrogenase, nadp-me2, malic enzyme 1, nadp malic enzyme, nadp-me1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
C4 photosynthetic carbon assimilation cycle, NADP-ME type, C4 photosynthetic carbon assimilation cycle, PEPCK type, gluconeogenesis I