Information on EC 1.1.1.397 - beta-methylindole-3-pyruvate reductase

for references in articles please use BRENDA:EC1.1.1.397
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
The enzyme, characterized from the bacterium Streptomyces griseus, participates in the biosynthesis of indolmycin, an antibacterial drug that inhibits the bacterial tryptophan---tRNA ligase (EC 6.1.1.2).
Specify your search results
Select one or more organisms in this record: ?
The expected taxonomic range for this enzyme is: Streptomyces griseus
Synonyms
ind2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD+ = (R)-3-(indol-3-yl)-2-oxobutanoate + NADH + H+
show the reaction diagram
-
-
-
-
PATHWAY SOURCE
PATHWAYS
Select items on the left to see more content.