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Information on EC 1.1.1.379 - (R)-mandelate dehydrogenase

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IUBMB Comments
The enzyme, found in bacteria and fungi, can also accept a number of substituted mandelate derivatives, such as 3-hydroxymandelate, 4-hydroxymandelate, 2-methoxymandelate, 4-hydroxy-3-methoxymandelate and 3-hydroxy-4-methoxymandelate. The enzyme has no activity with (S)-mandelate (cf. EC 1.1.99.31, (S)-mandelate dehydrogenase) [1,2]. The enzyme transfers the pro-R-hydrogen from NADH .
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The expected taxonomic range for this enzyme is: Rhodotorula graminis
Synonyms
D(-)-mandelate dehydrogenase, D-ManDH2, ManDH2, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
(R)-mandelate + NAD+ = phenylglyoxylate + NADH + H+
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