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Information on EC 1.1.1.369 - D-chiro-inositol 1-dehydrogenase

for references in articles please use BRENDA:EC1.1.1.369

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IUBMB Comments

The enzyme, found in the bacterium Bacillus subtilis, also catalyses the reaction of EC 1.1.1.18, inositol 2-dehydrogenase, and can also use D-glucose and D-xylose. It shows trace activity with D-ribose and D-fructose . It is part of a myo-inositol/D-chiro-inositol degradation pathway leading to acetyl-CoA.

The enzyme appears in viruses and cellular organisms

Synonyms
IDH, iolG, TM0414, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
1D-chiro-inositol + NAD+ = 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+
show the reaction diagram
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