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Information on EC 1.1.1.364 - dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

for references in articles please use BRENDA:EC1.1.1.364
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IUBMB Comments
The enzyme forms an activated deoxy-alpha-D-allose, which is converted to mycinose after attachment to the aglycones of several macrolide antibiotics, including tylosin, chalcomycin, dihydrochalcomycin, and mycinamicin II.
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The expected taxonomic range for this enzyme is: Streptomyces
Synonyms
GerKI, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dTDP-6-deoxy-alpha-D-allose + NAD(P)+ = dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NAD(P)H + H+
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