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Information on EC 1.1.1.273 - vellosimine dehydrogenase

for references in articles please use BRENDA:EC1.1.1.273

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IUBMB Comments

Also acts on related alkaloids with an endo-aldehyde group as vellosimine (same stereochemistry at C-16) but only slight activity with exo-aldehydes. Detected in many cell suspension cultures of plants from the family Apocynaceae.

The enzyme appears in viruses and cellular organisms
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
10-deoxysarpagine + NADP+ = vellosimine + NADPH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
ajmaline and sarpagine biosynthesis
Highest Expressing Human Cell Lines
Cell Line Links Gene Links