Information on EC 1.1.1.209 - 3(or 17)alpha-hydroxysteroid dehydrogenase

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EC Tree 1 Oxidoreductases 1.1 Acting on the CH-OH group of donors 1.1.1 With NAD⁺ or NADP⁺ as acceptor 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase

IUBMB Comments

Acts on the 3α-hydroxy group of androgens of the 5α-androstane series; and also, more slowly, on the 17α-hydroxy group of both androgenic and estrogenic substrates (cf. EC 1.1.1.51 3(or 17)β-hydroxysteroid dehydrogenase).

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

1.1.1.209
17beta-hydroxysteroids
testosterone
aldo-keto
3beta-hsd
neurosteroids
steroidogenesis
epitestosterone
17-ketosteroids
leydig
corticosterone
17alpha-hydroxysteroids
3alpha-hydroxysteroid
3beta-hydroxysteroid
5alpha-reductase
lh-stimulated
17alpha

Synonyms
akr1c21, 3beta- and 17beta-hydroxysteroid dehydrogenase, 3(17)alpha-hydroxysteroid dehydrogenase, 3(or 17)alpha-hydroxysteroid dehydrogenase, more