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Information on EC 1.1.1.187 - GDP-4-dehydro-D-rhamnose reductase

for references in articles please use BRENDA:EC1.1.1.187

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IUBMB Comments

The enzyme, which operates in the opposite direction to that shown, forms a mixture of GDP-α-D-rhamnose and its C-4 epimer, GDP-6-deoxy-α-D-talose. cf. EC 1.1.1.281, GDP-4-dehydro-6-deoxy-D-mannose reductase and EC 1.1.1.135, GDP-6-deoxy-D-talose 4-dehydrogenase.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
gdp-4-keto-6-deoxy-d-mannose reductase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
GDP-alpha-D-rhamnose + NAD(P)+ = GDP-4-dehydro-alpha-D-rhamnose + NAD(P)H + H+
show the reaction diagram
In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed
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