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12-ketochenodeoxycholic acid + NADH
cholic acid + NAD+
-
Substrates: -
Products: -
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12-oxo-cholic acid + NAD(P)H + H+
cholic acid + NAD(P)+
Substrates: 4.1% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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12-oxo-deoxycholic acid + NAD(P)H + H+
deoxycholic acid + NAD(P)+
Substrates: -
Products: -
r
12-oxochenodeoxycholic acid + NADP+
(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxycholan-24-oic acid + NADPH + H+
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Substrates: -
Products: -
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
3-oxocholic acid + NADPH + H+
cholic acid + NADP+
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl methyl ester + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl methyl ester + NADPH + H+
-
Substrates: -
Products: -
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5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
5beta-cholanic acid-3,7,12-trione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
5beta-cholanic acid-3alpha-ol-7,12-dione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
7-oxocholic acid + NADPH + H+
deoxycholic acid + NADP+
7alpha,12alpha-dihydroxy-5beta-cholanoate + NAD+
7alpha-hydroxy-12-oxo-5beta-cholanoate + NADH
-
Substrates: -
Products: -
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allocholate + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5alpha-cholan-24-oic acid + NADH
-
Substrates: -
Products: -
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allodeoxycholate + NAD+
3alpha-hydroxy-12-oxo-5alpha-cholan-24-oic acid + NADH
-
Substrates: -
Products: -
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cholate + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADH + H+
cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
cholic acid + NAD(P)+
12-oxocholic acid + NAD(P)H + H+
Substrates: 55.7% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
cholic acid + NAD+
3-oxocholic acid + NADH + H+
cholic acid + NADP+
12-ketochenodeoxycholic acid + NADPH + H+
-
Substrates: the assay is performed using an NADP+-regenerating system with acetone, NADPH, 2-propanol and alcohol dehydrogenase from Lactobacillus brevis or Thermoanaerobium brockii, overview
Products: -
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cholic acid + NADP+
3-oxocholic acid + NADPH + H+
deoxycholate + NADP+
12-oxo-lithocholic acid + NADPH + H+
deoxycholic acid + NAD(P)+
12-oxo-deoxycholic acid + NAD(P)H + H+
Substrates: 51.9% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
deoxycholic acid + NAD+
12-oxolithocholic acid + NADH + H+
-
Substrates: 100% activity
Products: -
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deoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NADH + H+
-
Substrates: -
Products: -
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deoxycholic acid + NADP+
12-oxolithocholic acid + NADH + H+
-
Substrates: 3.14% activity compared to NAD+
Products: -
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deoxycholic acid + NADP+
7-oxocholic acid + NADPH + H+
glycocholic acid + NAD(P)+
? + NAD(P)H + H+
Substrates: 60.3% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
glycodeoxycholic acid + NAD(P)+
? + NAD(P)H + H+
Substrates: 55.9% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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glycodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl glycine + NADH
glycodeoxycholic acid + NAD+
? + NADH + H+
-
Substrates: 97.8% activity compared to deoxycholic acid
Products: -
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glycodeoxycholic acid + NADP+
? + NADPH + H+
taurocholic acid + NAD(P)+
2-[(3alpha,7alpha-dihydroxy-12,24-dioxo-5beta-cholan-24-yl)amino]ethane-1-sulfonic acid + NAD(P)H + H+
Substrates: 53.8% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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taurocholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl taurine + NAD(P)H
taurocholic acid + NAD+
? + NADH + H+
-
Substrates: 98.95% activity compared to deoxycholic acid
Products: -
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taurodeoxychloic acid + NAD(P)+
? + NAD(P)H + H+
Substrates: 58.9% of the activity compared to the substrate 12-oxo-deoxycholic acid
Products: -
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taurodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl taurine + NADH
taurodeoxycholic acid + NAD+
? + NADH + H+
-
Substrates: 90.84% activity compared to deoxycholic acid
Products: -
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taurodeoxycholic acid + NADP+
? + NADPH + H+
additional information
?
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
Substrates: 3.65% activity compared to 12-oxolithocholic acid
Products: -
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
Substrates: 3.65% activity compared to 12-oxolithocholic acid
Products: -
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
Substrates: 4.16% activity compared to 12-oxolithocholic acid
Products: -
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
Substrates: 4.16% activity compared to 12-oxolithocholic acid
Products: -
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
-
Substrates: 9.55% activity compared to 12-oxolithocholic acid
Products: -
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12-oxochenodeoxycholic acid + NADPH + H+
7-oxodeoxycholic acid + NADP+
-
Substrates: 9.55% activity compared to 12-oxolithocholic acid
Products: -
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12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
-
Substrates: -
Products: -
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12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
-
Substrates: 19.6% activity compared to deoxycholic acid
Products: -
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12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
-
Substrates: -
Products: -
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12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
-
Substrates: 19.6% activity compared to deoxycholic acid
Products: -
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12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
-
Substrates: -
Products: -
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12-oxolithocholic acid + NADH + H+
deoxycholic acid + NAD+
-
Substrates: 19.6% activity compared to deoxycholic acid
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
-
Substrates: -
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
Substrates: 100% activity
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
Substrates: 100% activity
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
Substrates: 100% activity
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
Substrates: 100% activity
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
-
Substrates: 100% activity
Products: -
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12-oxolithocholic acid + NADPH + H+
deoxycholic acid + NADP+
-
Substrates: 100% activity
Products: -
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3-oxocholic acid + NADPH + H+
cholic acid + NADP+
Substrates: -
Products: -
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3-oxocholic acid + NADPH + H+
cholic acid + NADP+
Substrates: -
Products: -
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3-oxocholic acid + NADPH + H+
cholic acid + NADP+
Substrates: -
Products: -
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3-oxocholic acid + NADPH + H+
cholic acid + NADP+
Substrates: -
Products: -
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3-oxocholic acid + NADPH + H+
cholic acid + NADP+
-
Substrates: -
Products: -
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3-oxocholic acid + NADPH + H+
cholic acid + NADP+
-
Substrates: -
Products: -
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5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
?
5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
?
5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
?
5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
?
5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
-
Substrates: -
Products: -
?
5beta-cholanic acid-3,12-dione + NADPH + H+
3-oxodeoxycholic acid + NADP+
-
Substrates: -
Products: -
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5beta-cholanic acid-3,7,12-trione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
?
5beta-cholanic acid-3,7,12-trione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
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5beta-cholanic acid-3,7,12-trione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
-
Substrates: -
Products: -
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5beta-cholanic acid-3alpha-ol-7,12-dione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
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5beta-cholanic acid-3alpha-ol-7,12-dione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
Substrates: -
Products: -
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5beta-cholanic acid-3alpha-ol-7,12-dione + NADPH + H+
cholic acid + deoxycholic acid + 3-oxodeoxycholic acid + NADP+
-
Substrates: -
Products: -
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7-oxocholic acid + NADPH + H+
deoxycholic acid + NADP+
Substrates: -
Products: -
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7-oxocholic acid + NADPH + H+
deoxycholic acid + NADP+
-
Substrates: -
Products: -
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cholate + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADH + H+
-
Substrates: -
Products: -
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cholate + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADH + H+
-
Substrates: -
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: conversion of CA into 12-oxoursodeoxycholic acid
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: -
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: conversion of CA into 12-oxoursodeoxycholic acid
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: -
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: conversion of CA into 12-oxoursodeoxycholic acid
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
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Substrates: conversion of CA into 12-oxoursodeoxycholic acid
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: -
Products: -
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cholate + NADP+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H+
-
Substrates: conversion of CA into 12-oxoursodeoxycholic acid
Products: -
?
cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: -
Products: -
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cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: -
Products: -
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cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: -
Products: -
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cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: hardly accepts N6-modified NADP+ derivative
Products: -
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cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oic acid
Products: -
?, r
cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: -
Products: -
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cholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H
-
Substrates: -
Products: -
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cholic acid + NAD+
3-oxocholic acid + NADH + H+
-
Substrates: 98.5% activity compared to deoxycholic acid
Products: -
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cholic acid + NAD+
3-oxocholic acid + NADH + H+
-
Substrates: 98.5% activity compared to deoxycholic acid
Products: -
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cholic acid + NAD+
3-oxocholic acid + NADH + H+
-
Substrates: 98.5% activity compared to deoxycholic acid
Products: -
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cholic acid + NADP+
3-oxocholic acid + NADPH + H+
Substrates: 82.32% activity compared to deoxycholic acid
Products: -
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cholic acid + NADP+
3-oxocholic acid + NADPH + H+
Substrates: 80.51% activity compared to deoxycholic acid
Products: -
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cholic acid + NADP+
3-oxocholic acid + NADPH + H+
-
Substrates: 54.44% activity compared to deoxycholic acid
Products: -
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deoxycholate + NADP+
12-oxo-lithocholic acid + NADPH + H+
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Substrates: 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: i.e. 3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid
?
deoxycholate + NADP+
12-oxo-lithocholic acid + NADPH + H+
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Substrates: 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: i.e. 3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid
?
deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: -
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deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
-
Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: -
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deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: -
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deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: -
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deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: -
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deoxycholic acid + NAD(P)+
3alpha-hydroxy-12-oxo-5beta-cholan-24-oic acid + NAD(P)H + H+
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid
Products: -
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deoxycholic acid + NADP+
7-oxocholic acid + NADPH + H+
Substrates: 100% activity
Products: -
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deoxycholic acid + NADP+
7-oxocholic acid + NADPH + H+
Substrates: 100% activity
Products: -
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deoxycholic acid + NADP+
7-oxocholic acid + NADPH + H+
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Substrates: 100% activity
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl glycine
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl glycine
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl glycine
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: 81.08% activity compared to deoxycholic acid
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: 81.08% activity compared to deoxycholic acid
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: 81.08% activity compared to deoxycholic acid
Products: -
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glycocholic acid + NAD+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl glycine
Products: -
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glycodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholanoyl glycine
Products: -
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glycodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholanoyl glycine
Products: -
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glycodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholanoyl glycine
Products: -
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glycodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl glycine + NADH
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Substrates: i.e. 3alpha,12alpha-dihydroxy-5beta-cholanoyl glycine
Products: -
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glycodeoxycholic acid + NADP+
? + NADPH + H+
Substrates: 25.85% activity compared to deoxycholic acid
Products: -
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glycodeoxycholic acid + NADP+
? + NADPH + H+
Substrates: 24.17% activity compared to deoxycholic acid
Products: -
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glycodeoxycholic acid + NADP+
? + NADPH + H+
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Substrates: 6.36% activity compared to deoxycholic acid
Products: -
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taurocholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl taurine + NAD(P)H
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl taurine
Products: -
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taurocholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl taurine + NAD(P)H
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl taurine
Products: -
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taurocholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl taurine + NAD(P)H
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Substrates: i.e. 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl taurine
Products: -
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taurocholic acid + NAD(P)+
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanoyl taurine + NAD(P)H
-
Substrates: -
Products: -
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taurodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl taurine + NADH
-
Substrates: -
Products: -
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taurodeoxycholic acid + NAD+
3alpha-hydroxy-12-oxo-5beta-cholanoyl taurine + NADH
-
Substrates: -
Products: -
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taurodeoxycholic acid + NADP+
? + NADPH + H+
Substrates: 40.33% activity compared to deoxycholic acid
Products: -
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taurodeoxycholic acid + NADP+
? + NADPH + H+
Substrates: 45.08% activity compared to deoxycholic acid
Products: -
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taurodeoxycholic acid + NADP+
? + NADPH + H+
-
Substrates: 6.05% activity compared to deoxycholic acid
Products: -
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additional information
?
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Substrates: multistep conversion of cholic acid into ursodeoxycholic acid. Enzyme sources are 7alpha-HSDH from Clostridium absonum (crude extract), 12alpha-HSDH from Clostridium group P, 7beta-HSDH from Clostridium absonum
Products: -
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additional information
?
-
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Substrates: multistep conversion of cholic acid into ursodeoxycholic acid. Enzyme sources are 7alpha-HSDH from Clostridium absonum (crude extract), 12alpha-HSDH from Clostridium group P, 7beta-HSDH from Clostridium absonum
Products: -
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additional information
?
-
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Substrates: reaction product analysis confirmed by MS and NMR analyses
Products: -
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additional information
?
-
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Substrates: reaction product analysis confirmed by MS and NMR analyses
Products: -
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additional information
?
-
-
Substrates: no activity with chenodeoxycholic acid, glycochenodeoxycholic acid, taurochenodeoxycholic acid, 12-oxochenodeoxycholic acid, 3-oxodeoxycholic acid, and 3-oxocholic acid
Products: -
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additional information
?
-
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Substrates: no activity with chenodeoxycholic acid, glycochenodeoxycholic acid, taurochenodeoxycholic acid, 12-oxochenodeoxycholic acid, 3-oxodeoxycholic acid, and 3-oxocholic acid
Products: -
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additional information
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Substrates: no activity with chenodeoxycholic acid, glycochenodeoxycholic acid, taurochenodeoxycholic acid, 12-oxochenodeoxycholic acid, 3-oxodeoxycholic acid, and 3-oxocholic acid
Products: -
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additional information
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Substrates: no detection of the formation of 5beta-cholanic acid-3alpha-ol-12-one when cholic acid or its C-3'- or C-7'-oxo derivative is the substrate. No detection of oxidation of the 12alpha-hydroxyl group when deoxycholic acid is the substrate. No activity with 5beta-cholanic acid-12alpha-ol-3-one. No activity with NADH
Products: -
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additional information
?
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Substrates: no detection of the formation of 5beta-cholanic acid-3alpha-ol-12-one when cholic acid or its C-3'- or C-7'-oxo derivative is the substrate. No detection of oxidation of the 12alpha-hydroxyl group when deoxycholic acid is the substrate. No activity with 5beta-cholanic acid-12alpha-ol-3-one. No activity with NADH
Products: -
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additional information
?
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Substrates: no detection of the formation of 5beta-cholanic acid-3alpha-ol-12-one when cholic acid or its C-3- or C-7-oxo derivative is the substrate. No detection of oxidation of the 12alpha-hydroxyl group when deoxycholic acid is the substrate. No activity with 5beta-cholanic acid-12alpha-ol-3-one and 7-oxocholic acid. No activity with NADH
Products: -
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additional information
?
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Substrates: no detection of the formation of 5beta-cholanic acid-3alpha-ol-12-one when cholic acid or its C-3- or C-7-oxo derivative is the substrate. No detection of oxidation of the 12alpha-hydroxyl group when deoxycholic acid is the substrate. No activity with 5beta-cholanic acid-12alpha-ol-3-one and 7-oxocholic acid. No activity with NADH
Products: -
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additional information
?
-
-
Substrates: no detection of the formation of 5beta-cholanic acid-3alpha-ol-12-one when cholic acid or its C-3- or C-7-oxo derivative is the substrate. No detection of oxidation of the 12alpha-hydroxyl group when deoxycholic acid is the substrate. No activity with 5beta-cholanic acid-12alpha-ol-3-one. No activity with NADH
Products: -
-
additional information
?
-
-
Substrates: no detection of the formation of 5beta-cholanic acid-3alpha-ol-12-one when cholic acid or its C-3- or C-7-oxo derivative is the substrate. No detection of oxidation of the 12alpha-hydroxyl group when deoxycholic acid is the substrate. No activity with 5beta-cholanic acid-12alpha-ol-3-one. No activity with NADH
Products: -
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Ottolina, G.; Riva, S.; Carrea, G.; Danieli, B.; Buckmann, A.F.
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Eggerthella lenta
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Clostridium perfringens
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Brevibacterium fuscum
-
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Panichajakul, S.; Tawat, K.; Yoshida, T.; Taguchi, H.
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Brevibacterium fuscum
-
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Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid
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Clostridium sp.
brenda
Giovannini, P.P.; Grandini, A.; Perrone, D.; Pedrini, P.; Fantin, G.; Fogagnolo, M.
7alpha- and 12alpha-Hydroxysteroid dehydrogenases from Acinetobacter calcoaceticus lwoffii: a new integrated chemo-enzymatic route to ursodeoxycholic acid
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Acinetobacter lwoffii
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Kollerov, V.V.; Lobastova, T.G.; Monti, D.; Deshcherevskaya, N.O.; Ferrandi, E.E.; Fronza, G.; Riva, S.; Donova, M.V.
Deoxycholic acid transformations catalyzed by selected filamentous fungi
Steroids
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Curvularia lunata, Curvularia lunata VKM F-644
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Eggerthella lenta, Eggerthella lenta C592, Eggerthella lenta DSM 2243T
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