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Information on EC 1.1.1.149 - 20alpha-hydroxysteroid dehydrogenase

for references in articles please use BRENDA:EC1.1.1.149

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IUBMB Comments

Re-specific with respect to NAD(P)+ (cf. EC 1.1.1.62 17β-estradiol 17-dehydrogenase).

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
akr1c3, akr1c1, 20alpha-hsd, 20alpha-hydroxysteroid dehydrogenase, 20beta-hydroxysteroid dehydrogenase, akr1c9, akr1c14, 3alpha-hsor, 3alpha-hydroxysteroid oxidoreductase, aldo-keto reductase family 1 member c1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
17alpha,20alpha-dihydroxypregn-4-en-3-one + NAD(P)+ = 17alpha-hydroxyprogesterone + NAD(P)H + H+
show the reaction diagram
PATHWAY SOURCE
PATHWAYS