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The enzyme appears in viruses and cellular organisms
Synonyms short chain dehydrogenase/reductase, more
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D-ribose dehdrogenase (nicotinamide adenine dinucleotide phosphate)
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D-ribose dehydrogenase (NADP+)
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dehydrogenase, ribose (nicotinamide adenine dinucleotide phosphate)
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NADP-pentose-dehydrogenase
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NADP-ribose-1-dehydrogenase
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short chain dehydrogenase/reductase
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D-ribose + NADP+ + H2O = D-ribonate + NADPH + H+
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D-ribose:NADP+ 1-oxidoreductase
Also acts, more slowly, on D-xylose and other pentoses.
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5-O-trityl-alpha,beta-D-ribose + NADP+ + H2O
5-O-trityl-D-ribono-1,4-lactone + NADPH + H+
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Substrates: - Products: -
ir
D-arabinose + NADP+ + H2O
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Substrates: - Products: -
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D-ribose + NADP+ + H2O
D-ribonate + NADPH
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Substrates: - Products: -
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D-xylose + NADP+ + H2O
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Substrates: - Products: -
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NADP+
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HgCl2
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2.5 mM, 94% inhibition
iodoacetamide
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200 mM, 90% inhibition
NEM
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10 mM, 81% inhibition
p-chloromercuribenzoate
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0.2 mM, 92% inhibition
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9 - 10.3
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about 55% of maximal activity at pH 9.0 and at pH 10.3
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Highest Expressing Human Cell Lines
Filter by:
Cell Line Links
Gene Links
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expressed in Escherichia coli
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activity increases at the beginning of salt stress, 3.2- and 4.4-fold higher specific activity than controls grown in soil at the beginning of stress and after 1 day, respectively. Hypoosmotic stress does not induce the activity
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Schiwara, H.W.; Domschke, W.; Domagk, G.F.
Differenzierung verschiedener Zucker-Dehydrogenasen in der Schweineleber durch Disk-Elektrophorese und Ionenaustauschchromatograpie
Hoppe-Seyler's Z. Physiol. Chem.
349
1575-1581
1968
Sus scrofa
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Napora, K.; Wrodnigg, T.M.; Kosmus, P.; Thonhofer, M.; Robins, K.; Winkler, M.
Yarrowia lipolytica dehydrogenase/reductase: an enzyme tolerant for lipophilic compounds and carbohydrate substrates
Bioorg. Med. Chem. Lett.
23
3393-3395
2013
Yarrowia lipolytica
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Hyskova, V.; Pliskova, V.; Cerveny, V.; Ryslava, H.
NADP-dependent enzymes are involved in response to salt and hypoosmotic stress in cucumber plants
Gen. Physiol. Biophys.
36
247-258
2017
Cucumis sativus
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