EC Explorer

7.6.2.1

P-type phospholipid transporter

ATP + H₂O + phospholipid_{[side 1]} = ADP + phosphate + phospholipid_{[side 2]}

Mg²⁺-ATPase (ambiguous), flippase (ambiguous), aminophospholipid-transporting ATPase (ambiguous), phospholipid-translocating ATPase (ambiguous), phospholipid-transporting ATPase (ambiguous)

ATP phosphohydrolase (P-type, phospholipid-flipping)

A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. Different forms of the enzyme move phospholipids such as phosphatidylcholine, lyso-phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, phosphatidyglycerol, sphingomyelin and glucosylceramide from one membrane face to the other (‘flippase’).

created 2000 as EC 3.6.3.1 (EC 3.6.3.13 created 2000, incorporated 2001), transferred 2018 to EC 7.6.2.1