EC Explorer

EC 7.1.1.8 Details
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EC number
7.1.1.8
Accepted name
quinol—cytochrome-c reductase
Reaction
quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H+[side 2]
Other name(s)
ubiquinol—cytochrome-c reductase, coenzyme Q-cytochrome c reductase, dihydrocoenzyme Q-cytochrome c reductase, reduced ubiquinone-cytochrome c reductase, complex III (mitochondrial electron transport), ubiquinone-cytochrome c reductase, ubiquinol-cytochrome c oxidoreductase, reduced coenzyme Q-cytochrome c reductase, ubiquinone-cytochrome c oxidoreductase, reduced ubiquinone-cytochrome c oxidoreductase, mitochondrial electron transport complex III, ubiquinol-cytochrome c-2 oxidoreductase, ubiquinone-cytochrome b-c1 oxidoreductase, ubiquinol-cytochrome c2 reductase, ubiquinol-cytochrome c1 oxidoreductase, CoQH2-cytochrome c oxidoreductase, ubihydroquinol:cytochrome c oxidoreductase, coenzyme QH2-cytochrome c reductase, QH2:cytochrome c oxidoreductase, ubiquinol:ferricytochrome-c oxidoreductase
Systematic name
quinol:ferricytochrome-c oxidoreductase
CAS registry number
9027-03-6
Comment
The enzyme, often referred to as the cytochrome bc1 complex or complex III, is the third complex in the electron transport chain. It is present in the mitochondria of all aerobic eukaryotes and in the inner membranes of most bacteria. The mammalian enzyme contains cytochromes b-562, b-566 and c1, and a 2-iron ferredoxin. Depending on the organism and physiological conditions, the enzyme extrudes either two or four protons from the cytoplasmic to the non-cytoplasmic compartment (cf. EC 1.6.99.3, NADH dehydrogenase).
History
created 1978 as EC 1.10.2.2, modified 2013, transferred 2018 to EC 7.1.1.8