EC Explorer

7.1.1.3

ubiquinol oxidase (H⁺-transporting)

2 ubiquinol + O₂ + n H⁺_{[side 1]} = 2 ubiquinone + 2 H₂O + n H⁺_{[side 2]}

cyoABCD (gene names), cytochrome bo₃ oxidase, cytochrome bb₃ oxidase, cytochrome bo oxidase, ubiquinol:O₂ oxidoreductase (H⁺-transporting)

ubiquinol:oxygen oxidoreductase (H⁺-transporting)

Contains a dinuclear centre comprising two hemes, or heme and copper. This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane. The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo₃ oxidase it is 2. cf. EC 7.1.1.7, ubiquinol oxidase ubiquinol oxidase (electrogenic, proton-motive force generating).

created 2011 as EC 1.10.3.10, modified 2014, transferred 2018 to EC 7.1.1.3