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EC 4.6.1.6 Details
show Brenda entryEC number
4.6.1.6
Accepted name
cytidylate cyclase
Reaction
CTP = 3′,5′-cyclic CMP + diphosphate
Other name(s)
3′,5′-cyclic-CMP synthase,
cytidylyl cyclase,
cytidyl cyclase,
CTP diphosphate-lyase (cyclizing),
pycC (gene name) (ambiguous)
Systematic name
CTP diphosphate-lyase (cyclizing; 3′,5′-cyclic-CMP-forming)
CAS registry number
65357-82-6
Comment
In bacteria and archaea the enzyme's product, cCMP, functions as a second messenger in bacterial immunity against viruses. The enzyme is synthesized following phage infection and activates immune effectors that execute an antiviral response.
History
created 1989
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1 Oxidoreductases
4 Lyases
4.6.1.3 created 1978, deleted 2000 4.6.1.4 created 1978, modified 1983, deleted 2000 4.6.1.5 created 1989, deleted 2000 4.6.1.7 created 1989, deleted 2000 4.6.1.8 created 1992, deleted 2000 4.6.1.9 created 1992, deleted 2000 4.6.1.10 created 1999, deleted 2000 4.6.1.11 created 1999, deleted 2000
