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EC 4.6.1.1 Details
show Brenda entryEC number
4.6.1.1
Accepted name
adenylate cyclase
Reaction
ATP = 3′,5′-cyclic AMP + diphosphate
Other name(s)
adenylylcyclase,
adenyl cyclase,
3′,5′-cyclic AMP synthetase,
ATP diphosphate-lyase (cyclizing)
Systematic name
ATP diphosphate-lyase (cyclizing; 3′,5′-cyclic-AMP-forming)
CAS registry number
9012-42-4
Comment
Also acts on dATP to form 3′,5′-cyclic dAMP. Requires pyruvate. Activated by NAD+ in the presence of EC 2.4.2.31 NAD(P)+—arginine ADP-ribosyltransferase.
History
created 1972
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1 Oxidoreductases
4 Lyases
4.6.1.3 created 1978, deleted 2000 4.6.1.4 created 1978, modified 1983, deleted 2000 4.6.1.5 created 1989, deleted 2000 4.6.1.7 created 1989, deleted 2000 4.6.1.8 created 1992, deleted 2000 4.6.1.9 created 1992, deleted 2000 4.6.1.10 created 1999, deleted 2000 4.6.1.11 created 1999, deleted 2000
