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EC Explorer

EC 3.6.4.8 Details
EC number
3.6.4.8
Accepted name
proteasome ATPase
Reaction
ATP + H2O = ADP + phosphate
Systematic name
ATP phosphohydrolase (polypeptide-degrading)
Comment
Belongs to the AAA-type superfamily and, like EC 3.6.4.5 (minus-end-directed kinesin ATPase), is involved in channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome.
History
created 2000, deleted 2018