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EC 3.6.4.10 Details
EC number
3.6.4.10
Accepted name
non-chaperonin molecular chaperone ATPase
Reaction
ATP + H2O = ADP + phosphate
Other name(s)
molecular chaperone Hsc70 ATPase
Systematic name
ATP phosphohydrolase (polypeptide-polymerizing)
Comment
This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin.
History
created 2000