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EC 3.6.1.9 Details
EC number
3.6.1.9
Accepted name
nucleotide diphosphatase
Reaction
a nucleoside triphosphate + H2O = a nucleotide + diphosphate
Other name(s)
ENPP1 (gene name), nucleotide pyrophosphatase, nucleotide-sugar pyrophosphatase, nucleoside-triphosphate diphosphatase
Systematic name
nucleoside-triphosphate diphosphohydrolase
CAS registry number
9032-64-8
Comment
The enzyme preferentially hydrolyses ATP, but can also hydrolyse other nucleoside 5′ triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates. In vitro the enzyme also acts as a nucleotidohydrolase on ADP, NAD+, NADP+, FAD, and CoA.
History
created 1961 (EC 3.6.1.19 created 1972, incorporated 2016), modified 2016
EC Tree
3.6.1.4 created 1961, deleted 1965
3.6.1.32 created 1984, deleted 2000
3.6.1.33 created 1984, deleted 2000
3.6.1.34 created 1984, deleted 2000
3.6.1.35 created 1984, deleted 2000
3.6.1.36 created 1984, deleted 2000
3.6.1.37 created 1984, deleted 2000
3.6.1.38 created 1984, deleted 2000
3.6.1.46 created 2000, deleted 2003
3.6.1.47 created 2000, deleted 2003
3.6.1.48 created 2000, deleted 200
3.6.1.49 created 2000, deleted 2003
3.6.1.50 created 2000, deleted 2003
3.6.1.51 created 2000, deleted 2003