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EC 3.1.1.4 Details
EC number
3.1.1.4
Accepted name
phospholipase A2
Reaction
phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate
Other name(s)
lecithinase A, phosphatidase, phosphatidolipase, phospholipase A
Systematic name
phosphatidylcholine 2-acylhydrolase
CAS registry number
9001-84-7
Comment
Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position. Requires Ca2+.
History
created 1961, modified 1976, modified 1983
EC Tree
3.1.1.9 created 1961, deleted 1972
3.1.1.12 created 1961, deleted 1972
3.1.1.16 created 1961, deleted 1972
3.1.1.18 created 1961, deleted 1982
3.1.1.62 created 1989, deleted 1992
3.1.1.69 created 1992, deleted 2002