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EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.2 Acting on the aldehyde or oxo group of donors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.12 Acting on hydrogen as donor

1.12.1 With NAD⁺ or NADP⁺ as acceptor

1.12.2 With a cytochrome as acceptor

1.12.5 With a quinone or similar compound as acceptor

1.12.7 With an iron-sulfur protein as acceptor

1.12.98 With other, known, physiological acceptors

1.12.99 With unknown physiological acceptors

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.21.1 With NAD⁺ or NADP⁺ as acceptor

1.21.3 With oxygen as acceptor

1.21.4 With a disulfide as acceptor

1.21.98 With other, known, physiological acceptors

1.21.99 With unknown physiological acceptors

1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor

1.97 Other oxidoreductases

1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

4.1 Carbon-carbon lyases

4.2 Carbon-oxygen lyases

4.3 Carbon-nitrogen lyases

4.4 Carbon-sulfur lyases

4.5 Carbon-halide lyases

4.6 Phosphorus-oxygen lyases

4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)

4.6.1.1 adenylate cyclase

4.6.1.2 guanylate cyclase

4.6.1.3 created 1978, deleted 2000

4.6.1.4 created 1978, modified 1983, deleted 2000

4.6.1.5 created 1989, deleted 2000

4.6.1.6 cytidylate cyclase

4.6.1.7 created 1989, deleted 2000

4.6.1.8 created 1992, deleted 2000

4.6.1.9 created 1992, deleted 2000

4.6.1.10 created 1999, deleted 2000

4.6.1.11 created 1999, deleted 2000

4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

4.6.1.13 phosphatidylinositol diacylglycerol-lyase

4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase

4.6.1.15 FAD-AMP lyase (cyclizing)

4.6.1.16 tRNA-intron lyase

4.6.1.17 cyclic pyranopterin monophosphate synthase

4.6.1.18 pancreatic ribonuclease

4.6.1.19 ribonuclease T₂

4.6.1.20 ribonuclease U₂

4.6.1.21 Enterobacter ribonuclease

4.6.1.22 Bacillus subtilis ribonuclease

4.6.1.23 ribotoxin

4.6.1.24 ribonuclease T₁

4.6.1.25 bacteriophage T₄ restriction endoribonuclease RegB

4.6.1.26 uridylate cyclase

4.7 carbon-phosphorus lyases

4.8 Nitrogen-oxygen lyases

4.98 ATP-independent chelatases

4.99 Other lyases

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Release 2023.1 (January 2023)