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EC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.2 Acting on the aldehyde or oxo group of donors
1.3 Acting on the CH-CH group of donors
1.4 Acting on the CH-NH
2
group of donors
1.5 Acting on the CH-NH group of donors
1.6 Acting on NADH or NADPH
1.7 Acting on other nitrogenous compounds as donors
1.8 Acting on a sulfur group of donors
1.9 Acting on a heme group of donors
1.10 Acting on diphenols and related substances as donors
1.11 Acting on a peroxide as acceptor
1.12 Acting on hydrogen as donor
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)
1.14.2 With ascorbate as one donor (deleted sub-subclass)
1.14.3 With reduced pteridine as one donor (deleted sub-subclass)
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
1.14.11.1 γ-butyrobetaine dioxygenase
1.14.11.2 procollagen-proline 4-dioxygenase
1.14.11.3 pyrimidine-deoxynucleoside 2′-dioxygenase
1.14.11.4 procollagen-lysine 5-dioxygenase
1.14.11.5 created 1972, deleted 1976
1.14.11.6 thymine dioxygenase
1.14.11.7 procollagen-proline 3-dioxygenase
1.14.11.8 trimethyllysine dioxygenase
1.14.11.9 flavanone 3-dioxygenase
1.14.11.10 pyrimidine-deoxynucleoside 1′-dioxygenase
1.14.11.11 hyoscyamine (6
S
)-dioxygenase
1.14.11.12 gibberellin-44 dioxygenase
1.14.11.13 gibberellin 2β-dioxygenase
1.14.11.14 6β-hydroxyhyoscyamine epoxidase
1.14.11.15 gibberellin 3β-dioxygenase
1.14.11.16 peptide-aspartate β-dioxygenase
1.14.11.17 taurine dioxygenase
1.14.11.18 phytanoyl-CoA dioxygenase
1.14.11.19 anthocyanidin synthase
1.14.11.20 deacetoxyvindoline 4-hydroxylase
1.14.11.21 clavaminate synthase
1.14.11.22 flavone synthase
1.14.11.23 flavonol synthase
1.14.11.24 2′-deoxymugineic-acid 2′-dioxygenase
1.14.11.25 mugineic-acid 3-dioxygenase
1.14.11.26 deacetoxycephalosporin-C hydroxylase
1.14.11.27 [histone H3]-dimethyl-
L
-lysine
36
demethylase
1.14.11.28 proline 3-hydroxylase
1.14.11.29 hypoxia-inducible factor-proline dioxygenase
1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase
1.14.11.31 thebaine 6-
O
-demethylase
1.14.11.32 codeine 3-
O
-demethylase
1.14.11.33 DNA oxidative demethylase
1.14.11.34 2-oxoglutarate/
L
-arginine monooxygenase/decarboxylase (succinate-forming)
1.14.11.35 1-deoxypentalenic acid 11β-hydroxylase
1.14.11.36 pentalenolactone F synthase
1.14.11.37 kanamycin B dioxygenase
1.14.11.38 verruculogen synthase
1.14.11.39
L
-asparagine hydroxylase
1.14.11.40 enduracididine β-hydroxylase
1.14.11.41
L
-arginine hydroxylase
1.14.11.42 tRNA
Phe
(7-(3-amino-3-carboxypropyl)wyosine
37
-
C
2
)-hydroxylase
1.14.11.43 (
S
)-dichlorprop dioxygenase (2-oxoglutarate)
1.14.11.44 (
R
)-dichlorprop dioxygenase (2-oxoglutarate)
1.14.11.45
L
-isoleucine 4-hydroxylase
1.14.11.46 2-aminoethylphosphonate dioxygenase
1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase
1.14.11.48 xanthine dioxygenase
1.14.11.49 uridine-5′-phosphate dioxygenase
1.14.11.50 (–)-deoxypodophyllotoxin synthase
1.14.11.51 DNA
N
6
-methyladenine demethylase
1.14.11.52 validamycin A dioxygenase
1.14.11.53 mRNA
N
6
-methyladenine demethylase
1.14.11.54 mRNA
N
1
-methyladenine demethylase
1.14.11.55 ectoine hydroxylase
1.14.11.56
L
-proline
cis
-4-hydroxylase
1.14.11.57
L
-proline
trans
-4-hydroxylase
1.14.11.58 ornithine lipid ester-linked acyl 2-hydroxylase
1.14.11.59 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase
1.14.11.60 scopoletin 8-hydroxylase
1.14.11.61 feruloyl-CoA 6-hydroxylase
1.14.11.62
trans
-4-coumaroyl-CoA 2-hydroxylase
1.14.11.63 peptidyl-lysine (3
S
)-dioxygenase
1.14.11.64 glutarate dioxygenase
1.14.11.65 [histone H3]-dimethyl-
L
-lysine
9
demethylase
1.14.11.66 [histone H3]-trimethyl-
L
-lysine
9
demethylase
1.14.11.67 [histone H3]-trimethyl-
L
-lysine
4
demethylase
1.14.11.68 [histone H3]-trimethyl-
L
-lysine
27
demethylase
1.14.11.69 [histone H3]-trimethyl-
L
-lysine
36
demethylase
1.14.11.70 7-deoxycylindrospermopsin hydroxylase
1.14.11.71 methylphosphonate hydroxylase
1.14.11.72 [2-(trimethylamino)ethyl]phosphonate dioxygenase
1.14.11.73 [protein]-arginine 3-hydroxylase
1.14.11.74
L
-isoleucine 3
1
-dioxygenase
1.14.11.75 3
1
-hydroxy-
L
-isoleucine 4-dioxygenase
1.14.11.76
L
-glutamate 3(
R
)-hydroxylase
1.14.11.77 alkyl sulfatase
1.14.11.78 (
R
)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase
1.14.11.79 protein-
L
-histidine (3
S
)-3-hydroxylase
1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor
1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
1.14.19 With oxidation of a pair of donors resulting in the reduction of O
2
to two molecules of water
1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated
1.14.99 Miscellaneous
1.15 Acting on superoxide as acceptor
1.16 Oxidizing metal ions
1.16.1 With NAD
+
or NADP
+
as acceptor
1.16.3 With oxygen as acceptor
1.16.5 With a quinone or similar compound as acceptor
1.16.8 With a flavin as acceptor
1.16.9 With a copper protein as acceptor
1.16.98 With other, known, physiological acceptors
1.16.99 With unknown physiological acceptors
1.17 Acting on CH or CH
2
groups
1.18 Acting on iron-sulfur proteins as donors
1.19 Acting on reduced flavodoxin as donor
1.20 Acting on phosphorus or arsenic in donors
1.21 Catalysing the reaction X-H + Y-H = X-Y
1.21.1 With NAD
+
or NADP
+
as acceptor
1.21.3 With oxygen as acceptor
1.21.4 With a disulfide as acceptor
1.21.98 With other, known, physiological acceptors
1.21.99 With unknown physiological acceptors
1.22 Acting on halogen in donors
1.23 Reducing C-O-C group as acceptor
1.97 Other oxidoreductases
1.98 Enzymes using H
2
as reductant (deleted subclass)
1.99 Other enzymes using O
2
as oxidant (deleted subclass)
2 Transferases
3 Hydrolases
3.1 Acting on ester bonds
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse
O-
and
S-
glycosyl compounds
3.2.2 Hydrolysing
N-
glycosyl compounds
3.2.3 Hydrolysing S-glycosyl compounds (deleted sub-subclass)
3.3 Acting on ether bonds
3.4 Acting on peptide bonds (peptidases)
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.6 Acting on acid anhydrides
3.7 Acting on carbon-carbon bonds
3.8 Acting on halide bonds
3.9 Acting on phosphorus-nitrogen bonds
3.10 Acting on sulfur-nitrogen bonds
3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
3.11 Acting on carbon-phosphorus bonds
3.12 Acting on sulfur-sulfur bonds
3.13 Acting on carbon-sulfur bonds
4 Lyases
5 Isomerases
6 Ligases
7 Translocases