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EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.2 Acting on the aldehyde or oxo group of donors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.5.1 With NAD⁺ or NADP⁺ as acceptor

1.5.3 With oxygen as acceptor

1.5.4 With a disulfide as acceptor

1.5.5 With a quinone or similar compound as acceptor

1.5.7 With an iron-sulfur protein as acceptor

1.5.8 With a flavin or flavoprotein as acceptor

1.5.98 With other, known, physiological acceptors

1.5.99 With unknown physiological acceptors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.12 Acting on hydrogen as donor

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.13.1. undefined

1.13.11 With incorporation of two atoms of oxygen

1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

1.13.99 Miscellaneous

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.21.1 With NAD⁺ or NADP⁺ as acceptor

1.21.3 With oxygen as acceptor

1.21.4 With a disulfide as acceptor

1.21.98 With other, known, physiological acceptors

1.21.99 With unknown physiological acceptors

1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor

1.97 Other oxidoreductases

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

3.1 Acting on ester bonds

3.2 Glycosylases

3.3 Acting on ether bonds

3.4 Acting on peptide bonds (peptidases)

3.4.1 α-Amino-acyl-peptide hydrolases (deleted sub-subclass)

3.4.2 Peptidyl-amino-acid hydrolases (deleted sub-subclass)

3.4.3 Dipeptide hydrolases (deleted sub-subclass)

3.4.4 Peptidyl peptide hydrolases (deleted sub-subclass)

3.4.11 Aminopeptidases

3.4.12 Peptidylamino-acid hydrolases or acylamino-acid hydrolases (deleted sub-subclass)

3.4.13 Dipeptidases

3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases

3.4.15 Peptidyl-dipeptidases

3.4.16 Serine-type carboxypeptidases

3.4.17 Metallocarboxypeptidases

3.4.18 Cysteine-type carboxypeptidases

3.4.19 Omega peptidases

3.4.19.1 acylaminoacyl-peptidase

3.4.19.2 peptidyl-glycinamidase

3.4.19.3 pyroglutamyl-peptidase I

3.4.19.4 created 1989, deleted 1992

3.4.19.5 β-aspartyl-peptidase

3.4.19.6 pyroglutamyl-peptidase II

3.4.19.7 N-formylmethionyl-peptidase

3.4.19.8 created 1992, deleted 2000

3.4.19.9 folate γ-glutamyl hydrolase

3.4.19.10 created 1972 as EC 3.4.12.5, transferred 1978 to EC 3.4.17.7, transferred 1992 to EC 3.4.19.10, deleted 1997

3.4.19.11 γ-D-glutamyl-meso-diaminopimelate peptidase

3.4.19.12 ubiquitinyl hydrolase 1

3.4.19.13 glutathione γ-glutamate hydrolase

3.4.19.14 leukotriene-C₄ hydrolase

3.4.19.15 desampylase

3.4.19.16 glucosinolate γ-glutamyl hydrolase

3.4.21 Serine endopeptidases

3.4.22 Cysteine endopeptidases

3.4.23 Aspartic endopeptidases

3.4.24 Metalloendopeptidases

3.4.25 Threonine endopeptidases

3.4.99 Endopeptidases of unknown catalytic mechanism (sub-subclass is currently empty)

3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

3.6 Acting on acid anhydrides

3.7 Acting on carbon-carbon bonds

3.8 Acting on halide bonds

3.9 Acting on phosphorus-nitrogen bonds

3.10 Acting on sulfur-nitrogen bonds

3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)

3.11 Acting on carbon-phosphorus bonds

3.12 Acting on sulfur-sulfur bonds

3.13 Acting on carbon-sulfur bonds

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Release 2023.1 (January 2023)