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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.2 Acting on the aldehyde or oxo group of donors
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD
+
or NADP
+
as acceptor
1.3.2 With a cytochrome as acceptor
1.3.3 With oxygen as acceptor
1.3.4 With a disulfide as acceptor
1.3.5 With a quinone or related compound as acceptor
1.3.7 With an iron-sulfur protein as acceptor
1.3.8 With a flavin as acceptor
1.3.98 With other, known, physiological acceptors
1.3.99 With unknown physiological acceptors
1.4 Acting on the CH-NH
2
group of donors
1.5 Acting on the CH-NH group of donors
1.6 Acting on NADH or NADPH
1.7 Acting on other nitrogenous compounds as donors
1.8 Acting on a sulfur group of donors
1.9 Acting on a heme group of donors
1.10 Acting on diphenols and related substances as donors
1.11 Acting on a peroxide as acceptor
1.12 Acting on hydrogen as donor
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.15 Acting on superoxide as acceptor
1.15.1 Acting on superoxide as acceptor (only sub-subclass identified to date)
1.16 Oxidizing metal ions
1.17 Acting on CH or CH
2
groups
1.18 Acting on iron-sulfur proteins as donors
1.19 Acting on reduced flavodoxin as donor
1.20 Acting on phosphorus or arsenic in donors
1.21 Catalysing the reaction X-H + Y-H = X-Y
1.21.1 With NAD
+
or NADP
+
as acceptor
1.21.3 With oxygen as acceptor
1.21.4 With a disulfide as acceptor
1.21.98 With other, known, physiological acceptors
1.21.99 With unknown physiological acceptors
1.22 Acting on halogen in donors
1.23 Reducing C-O-C group as acceptor
1.97 Other oxidoreductases
1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses
1.98 Enzymes using H
2
as reductant (deleted subclass)
1.99 Other enzymes using O
2
as oxidant (deleted subclass)
2 Transferases
2.1 Transferring one-carbon groups
2.2 Transferring aldehyde or ketonic groups
2.3 Acyltransferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.2 Pentosyltransferases
2.4.2.1 purine-nucleoside phosphorylase
2.4.2.2 pyrimidine-nucleoside phosphorylase
2.4.2.3 uridine phosphorylase
2.4.2.4 thymidine phosphorylase
2.4.2.5 nucleoside ribosyltransferase
2.4.2.6 nucleoside deoxyribosyltransferase
2.4.2.7 adenine phosphoribosyltransferase
2.4.2.8 hypoxanthine phosphoribosyltransferase
2.4.2.9 uracil phosphoribosyltransferase
2.4.2.10 orotate phosphoribosyltransferase
2.4.2.11 nicotinate phosphoribosyltransferase
2.4.2.12 nicotinamide phosphoribosyltransferase
2.4.2.13 created 1961, deleted 1965
2.4.2.14 amidophosphoribosyltransferase
2.4.2.15 guanosine phosphorylase
2.4.2.16 urate-ribonucleoside phosphorylase
2.4.2.17 ATP phosphoribosyltransferase
2.4.2.18 anthranilate phosphoribosyltransferase
2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating)
2.4.2.20 dioxotetrahydropyrimidine phosphoribosyltransferase
2.4.2.21 nicotinate-nucleotide—dimethylbenzimidazole phosphoribosyltransferase
2.4.2.22 xanthine phosphoribosyltransferase
2.4.2.23 deoxyuridine phosphorylase
2.4.2.24 1,4-β-
D
-xylan synthase
2.4.2.25 flavone apiosyltransferase
2.4.2.26 protein xylosyltransferase
2.4.2.27 dTDP-dihydrostreptose—streptidine-6-phosphate dihydrostreptosyltransferase
2.4.2.28
S
-methyl-5′-thioadenosine phosphorylase
2.4.2.29 tRNA-guanosine
34
preQ
1
transglycosylase
2.4.2.30 NAD
+
ADP-ribosyltransferase
2.4.2.31 NAD
+
—protein-arginine ADP-ribosyltransferase
2.4.2.32 dolichyl-phosphate
D
-xylosyltransferase
2.4.2.33 dolichyl-xylosyl-phosphate—protein xylosyltransferase
2.4.2.34 indolylacetylinositol arabinosyltransferase
2.4.2.35 flavonol-3-
O
-glycoside xylosyltransferase
2.4.2.36 NAD
+
—diphthamide ADP-ribosyltransferase
2.4.2.37 NAD
+
—dinitrogen-reductase ADP-
D
-ribosyltransferase
2.4.2.38 glycoprotein 2-β-
D
-xylosyltransferase
2.4.2.39 xyloglucan 6-xylosyltransferase
2.4.2.40 zeatin
O
-β-
D
-xylosyltransferase
2.4.2.41 xylogalacturonan β-1,3-xylosyltransferase
2.4.2.42 UDP-
D
-xylose:β-
D
-glucoside α-1,3-
D
-xylosyltransferase
2.4.2.43 lipid IV
A
4-amino-4-deoxy-
L
-arabinosyltransferase
2.4.2.44
S
-methyl-5′-thioinosine phosphorylase
2.4.2.45 decaprenyl-phosphate phosphoribosyltransferase
2.4.2.46 galactan 5-
O
-arabinofuranosyltransferase
2.4.2.47 arabinofuranan 3-
O
-arabinosyltransferase
2.4.2.48 tRNA-guanine
15
transglycosylase
2.4.2.49 neamine phosphoribosyltransferase
2.4.2.50 cyanidin 3-
O
-galactoside 2′′-
O
-xylosyltransferase
2.4.2.51 anthocyanidin 3-
O
-glucoside 2′′′-
O
-xylosyltransferase
2.4.2.52 triphosphoribosyl-dephospho-CoA synthase
2.4.2.53 undecaprenyl-phosphate 4-deoxy-4-formamido-
L
-arabinose transferase
2.4.2.54 β-ribofuranosylphenol 5′-phosphate synthase
2.4.2.55 nicotinate
D
-ribonucleotide:phenol phospho-
D
-ribosyltransferase
2.4.2.56 kaempferol 3-
O
-xylosyltransferase
2.4.2.57 AMP phosphorylase
2.4.2.58 hydroxyproline
O
-arabinosyltransferase
2.4.2.59 sulfide-dependent adenosine diphosphate thiazole synthase
2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase
2.4.2.61 α-dystroglycan β1,4-xylosyltransferase
2.4.2.62 xylosyl α-1,3-xylosyltransferase
2.4.2.63 EGF-domain serine xylosyltransferase
2.4.2.64 tRNA-guanosine
34
queuine transglycosylase
2.4.3 Sialyltransferases
2.4.99 Transferring other glycosyl groups
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.6 Transferring nitrogenous groups
2.7 Transferring phosphorus-containing groups
2.8 Transferring sulfur-containing groups
2.9 Transferring selenium-containing groups
2.10 Transferring molybdenum- or tungsten-containing groups
3 Hydrolases
3.1 Acting on ester bonds
3.2 Glycosylases
3.3 Acting on ether bonds
3.4 Acting on peptide bonds (peptidases)
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.6 Acting on acid anhydrides
3.7 Acting on carbon-carbon bonds
3.8 Acting on halide bonds
3.9 Acting on phosphorus-nitrogen bonds
3.10 Acting on sulfur-nitrogen bonds
3.11 Acting on carbon-phosphorus bonds
3.12 Acting on sulfur-sulfur bonds
3.13 Acting on carbon-sulfur bonds
4 Lyases
5 Isomerases
6 Ligases
7 Translocases