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1 Oxidoreductases (9631 organisms)

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1.1 Acting on the CH-OH group of donors (6982 organisms)

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1.2 Acting on the aldehyde or oxo group of donors (1227 organisms)

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1.3 Acting on the CH-CH group of donors (1050 organisms)

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1.4 Acting on the CH-NH₂ group of donors (1047 organisms)

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1.5 Acting on the CH-NH group of donors (745 organisms)

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1.6 Acting on NADH or NADPH (328 organisms)

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1.7 Acting on other nitrogenous compounds as donors (567 organisms)

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1.8 Acting on a sulfur group of donors (765 organisms)

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1.9 Acting on a heme group of donors (185 organisms)

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1.10 Acting on diphenols and related substances as donors (444 organisms)

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1.11 Acting on a peroxide as acceptor (825 organisms)

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1.12 Acting on hydrogen as donor (259 organisms)

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1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) (861 organisms)

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1.13.1. undefined

1.13.11 With incorporation of two atoms of oxygen (762 organisms)

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1.13.11.1 catechol 1,2-dioxygenase (98 organisms)

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1.13.11.2 catechol 2,3-dioxygenase (102 organisms)

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1.13.11.3 protocatechuate 3,4-dioxygenase (47 organisms)

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1.13.11.4 gentisate 1,2-dioxygenase (42 organisms)

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1.13.11.5 homogentisate 1,2-dioxygenase (42 organisms)

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1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase (15 organisms)

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1.13.11.7 created 1965 as EC 1.13.1.7, transferred 1972 to EC 1.13.11.7, deleted 1980

1.13.11.8 protocatechuate 4,5-dioxygenase (14 organisms)

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1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase (7 organisms)

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1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase (1 organism)

1.13.11.11 tryptophan 2,3-dioxygenase (15 organisms)

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1.13.11.12 linoleate 13S-lipoxygenase (30 organisms)

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1.13.11.13 ascorbate 2,3-dioxygenase

1.13.11.14 2,3-dihydroxybenzoate 3,4-dioxygenase (6 organisms)

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1.13.11.15 3,4-dihydroxyphenylacetate 2,3-dioxygenase (26 organisms)

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1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase (4 organisms)

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1.13.11.17 indole 2,3-dioxygenase (5 organisms)

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1.13.11.18 persulfide dioxygenase (20 organisms)

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1.13.11.19 cysteamine dioxygenase (14 organisms)

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1.13.11.20 cysteine dioxygenase (23 organisms)

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1.13.11.21 created 1972, deleted 2001

1.13.11.22 caffeate 3,4-dioxygenase (1 organism)

1.13.11.23 2,3-dihydroxyindole 2,3-dioxygenase (1 organism)

1.13.11.24 quercetin 2,3-dioxygenase (18 organisms)

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1.13.11.25 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase (2 organisms)

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1.13.11.26 peptide-tryptophan 2,3-dioxygenase (4 organisms)

1.13.11.27 4-hydroxyphenylpyruvate dioxygenase (40 organisms)

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1.13.11.28 2,3-dihydroxybenzoate 2,3-dioxygenase (1 organism)

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1.13.11.29 stizolobate synthase (1 organism)

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1.13.11.30 stizolobinate synthase (1 organism)

1.13.11.31 arachidonate 12-lipoxygenase (28 organisms)

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1.13.11.32 2-nitropropane dioxygenase (3 organisms)

1.13.11.33 arachidonate 15-lipoxygenase (32 organisms)

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1.13.11.34 arachidonate 5-lipoxygenase (16 organisms)

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1.13.11.35 pyrogallol 1,2-oxygenase (1 organism)

1.13.11.36 chloridazon-catechol dioxygenase (2 organisms)

1.13.11.37 hydroxyquinol 1,2-dioxygenase (27 organisms)

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1.13.11.38 1-hydroxy-2-naphthoate 1,2-dioxygenase (9 organisms)

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1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase (55 organisms)

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1.13.11.40 arachidonate 8-lipoxygenase (7 organisms)

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1.13.11.41 2,4′-dihydroxyacetophenone dioxygenase (4 organisms)

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1.13.11.42 indoleamine-pyrrole 2,3-dioxygenase

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1.13.11.43 lignostilbene αβ-dioxygenase (3 organisms)

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1.13.11.44 linoleate diol synthase

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1.13.11.45 linoleate 11-lipoxygenase (7 organisms)

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1.13.11.46 4-hydroxymandelate synthase (3 organisms)

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1.13.11.47 3-hydroxy-4-oxoquinoline 2,4-dioxygenase (6 organisms)

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1.13.11.48 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase (8 organisms)

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1.13.11.49 chlorite O₂-lyase (25 organisms)

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1.13.11.50 acetylacetone-cleaving enzyme (1 organism)

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1.13.11.51 9-cis-epoxycarotenoid dioxygenase (50 organisms)

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1.13.11.52 indoleamine 2,3-dioxygenase (50 organisms)

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1.13.11.53 acireductone dioxygenase (Ni²⁺-requiring) (9 organisms)

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1.13.11.54 acireductone dioxygenase [iron(II)-requiring] (10 organisms)

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1.13.11.55 sulfur oxygenase/reductase (23 organisms)

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1.13.11.56 1,2-dihydroxynaphthalene dioxygenase (5 organisms)

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1.13.11.57 gallate dioxygenase (6 organisms)

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1.13.11.58 linoleate 9S-lipoxygenase (22 organisms)

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1.13.11.59 torulene dioxygenase (2 organisms)

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1.13.11.60 linoleate 8R-lipoxygenase (12 organisms)

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1.13.11.61 linolenate 9R-lipoxygenase (5 organisms)

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1.13.11.62 linoleate 10R-lipoxygenase (4 organisms)

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1.13.11.63 β-carotene 15,15′-dioxygenase (28 organisms)

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1.13.11.64 5-nitrosalicylate dioxygenase (1 organism)

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1.13.11.65 carotenoid isomerooxygenase (6 organisms)

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1.13.11.66 hydroquinone 1,2-dioxygenase (13 organisms)

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1.13.11.67 8′-apo-β-carotenoid 14′,13′-cleaving dioxygenase (3 organisms)

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1.13.11.68 9-cis-β-carotene 9′,10′-cleaving dioxygenase (10 organisms)

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1.13.11.69 carlactone synthase (5 organisms)

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1.13.11.70 all-trans-10′-apo-β-carotenal 13,14-cleaving dioxygenase (8 organisms)

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1.13.11.71 carotenoid-9′,10′-cleaving dioxygenase (13 organisms)

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1.13.11.72 2-hydroxyethylphosphonate dioxygenase (2 organisms)

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1.13.11.73 methylphosphonate synthase (2 organisms)

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1.13.11.74 2-aminophenol 1,6-dioxygenase (6 organisms)

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1.13.11.75 all-trans-8′-apo-β-carotenal 15,15′-oxygenase (5 organisms)

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1.13.11.76 2-amino-5-chlorophenol 1,6-dioxygenase (1 organism)

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1.13.11.77 oleate 10S-lipoxygenase (5 organisms)

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1.13.11.78 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) (4 organisms)

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1.13.11.79 aerobic 5,6-dimethylbenzimidazole synthase (6 organisms)

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1.13.11.80 (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase (3 organisms)

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1.13.11.81 7,8-dihydroneopterin oxygenase (3 organisms)

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1.13.11.82 8′-apo-carotenoid 13,14-cleaving dioxygenase

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1.13.11.83 4-hydroxy-3-prenylphenylpyruvate oxygenase (2 organisms)

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1.13.11.84 crocetin dialdehyde synthase (4 organisms)

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1.13.11.85 exo-cleaving rubber dioxygenase (8 organisms)

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1.13.11.86 5-aminosalicylate 1,2-dioxygenase (2 organisms)

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1.13.11.87 endo-cleaving rubber dioxygenase (12 organisms)

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1.13.11.88 isoeugenol monooxygenase (5 organisms)

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1.13.11.89 (hydroxymethyl)phosphonate dioxygenase (2 organisms)

1.13.11.90 [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming) (1 organism)

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1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) (107 organisms)

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1.13.99 Miscellaneous (20 organisms)

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1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen (2405 organisms)

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1.15 Acting on superoxide as acceptor (381 organisms)

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1.16 Oxidizing metal ions (233 organisms)

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1.17 Acting on CH or CH₂ groups (403 organisms)

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1.18 Acting on iron-sulfur proteins as donors (199 organisms)

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1.19 Acting on reduced flavodoxin as donor (21 organisms)

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1.20 Acting on phosphorus or arsenic in donors (106 organisms)

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1.21 Catalysing the reaction X-H + Y-H = X-Y (151 organisms)

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1.22 Acting on halogen in donors

1.22.1 With NAD⁺ or NADP⁺ as acceptor

1.23 Reducing C-O-C group as acceptor (32 organisms)

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1.97 Other oxidoreductases (134 organisms)

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1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

2 Transferases (7171 organisms)

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3 Hydrolases (11482 organisms)

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4 Lyases (5139 organisms)

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5 Isomerases (2099 organisms)

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6 Ligases (1565 organisms)

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7 Translocases (1096 organisms)

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