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1 Oxidoreductases (9634 organisms)

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1.1 Acting on the CH-OH group of donors (6909 organisms)

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1.2 Acting on the aldehyde or oxo group of donors (1222 organisms)

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1.3 Acting on the CH-CH group of donors (1032 organisms)

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1.4 Acting on the CH-NH₂ group of donors (1047 organisms)

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1.5 Acting on the CH-NH group of donors (745 organisms)

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1.6 Acting on NADH or NADPH (359 organisms)

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1.7 Acting on other nitrogenous compounds as donors (568 organisms)

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1.8 Acting on a sulfur group of donors (747 organisms)

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1.8.1 With NAD⁺ or NADP⁺ as acceptor (313 organisms)

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1.8.2 With a cytochrome as acceptor (51 organisms)

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1.8.3 With oxygen as acceptor (109 organisms)

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1.8.4 With a disulfide as acceptor (205 organisms)

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1.8.5 With a quinone or similar compound as acceptor (89 organisms)

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1.8.6 With a nitrogenous group as acceptor (deleted sub-subclass)

1.8.7 With an iron-sulfur protein as acceptor (40 organisms)

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1.8.98 With other, known, physiological acceptors (35 organisms)

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1.8.99 With unknown physiological acceptors (128 organisms)

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1.9 Acting on a heme group of donors (339 organisms)

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1.10 Acting on diphenols and related substances as donors (444 organisms)

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1.11 Acting on a peroxide as acceptor (798 organisms)

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1.11.1 Peroxidases (782 organisms)

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1.11.2 Peroxygenases (36 organisms)

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1.12 Acting on hydrogen as donor (258 organisms)

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1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) (861 organisms)

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1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen (2371 organisms)

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1.15 Acting on superoxide as acceptor (381 organisms)

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1.16 Oxidizing metal ions (235 organisms)

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1.16.1 With NAD⁺ or NADP⁺ as acceptor (172 organisms)

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1.16.3 With oxygen as acceptor (73 organisms)

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1.16.5 With a quinone or similar compound as acceptor

1.16.8 With a flavin as acceptor (1 organism)

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1.16.9 With a copper protein as acceptor (3 organisms)

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1.16.98 With other, known, physiological acceptors

1.17 Acting on CH or CH₂ groups (401 organisms)

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1.18 Acting on iron-sulfur proteins as donors (198 organisms)

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1.19 Acting on reduced flavodoxin as donor (21 organisms)

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1.20 Acting on phosphorus or arsenic in donors (105 organisms)

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1.21 Catalysing the reaction X-H + Y-H = X-Y (149 organisms)

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1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor (32 organisms)

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1.97 Other oxidoreductases (134 organisms)

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1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

2 Transferases (6601 organisms)

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3 Hydrolases (9513 organisms)

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4 Lyases (5106 organisms)

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5 Isomerases (2066 organisms)

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6 Ligases (1540 organisms)

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6.1 Forming carbon-oxygen bonds (376 organisms)

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6.2 Forming carbon-sulfur bonds (418 organisms)

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6.3 Forming carbon-nitrogen bonds (793 organisms)

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6.4 Forming carbon-carbon bonds (203 organisms)

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6.5 Forming phosphoric-ester bonds (241 organisms)

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6.6 Forming nitrogen—metal bonds (26 organisms)

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7 Translocases (833 organisms)

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