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EC 1.14.14.141 Details
show Brenda entryEC number
1.14.14.141
Accepted name
psoralen synthase
Reaction
(+)-marmesin + [reduced NADPH—hemoprotein reductase] + O2 = psoralen + [oxidized NADPH—hemoprotein reductase] + acetone + 2 H2O
Other name(s)
CYP71AJ1
Systematic name
(+)-marmesin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase
Comment
This microsomal cytochrome P-450 (heme-thiolate) enzyme is rather specific for (+)-marmesin, although it can also accept 5-hydroxymarmesin to a much lesser extent. Furanocoumarins protect plants from fungal invasion and herbivore attack. (+)-Columbianetin, the angular furanocoumarin analogue of the linear furanocoumarin (+)-marmesin, acts as a competitive inhibitor even though it is not a substrate.
History
created 2007 as EC 1.14.13.102, transferred 2018 to EC 1.14.14.141
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.19.1 stearoyl-CoA 9-desaturase
