EC Explorer

7.4.2.1

ABC-type polar-amino-acid transporter

ATP + H₂O + polar amino acid-[polar amino acid-binding protein]_{[side 1]} = ADP + phosphate + polar amino acid_{[side 2]} + [polar amino acid-binding protein]_{[side 1]}

histidine permease, polar-amino-acid-transporting ATPase

ATP phosphohydrolase (ABC-type, polar-amino-acid-importing)

An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein and mediates the import of polar amino acids. This entry comprises bacterial enzymes that import His, Arg, Lys, Glu, Gln, Asp, ornithine, octopine and nopaline.

created 2000 as EC 3.6.3.21, transferred 2018 to EC 7.4.2.1