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EC 5.1.3.37 Details
EC number
5.1.3.37
Accepted name
mannuronan 5-epimerase
Reaction
[mannuronan]-β-D-mannuronate = [alginate]-α-L-guluronate
Other name(s)
algG (gene name), alginate epimerase, C5-mannuronan epimerase, mannuronan C-5-epimerase
Systematic name
[mannuronan]-β-D-mannuronate 5-epimerase
Comment
The enzyme epimerizes the C-5 bond in some β-D-mannuronate residues in mannuronan, converting them to α-L-guluronate residues, and thus modifying the mannuronan into alginate. It is found in brown algae and alginate-producing bacterial species from the Pseudomonas and Azotobacter genera.
History
created 2015
EC Tree
1.14.14.2 created 1972, deleted 1976
1.14.14.4 created 2000, deleted 2002