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EC 6.3.2.41 Details
show Brenda entryEC number
6.3.2.41
Accepted name
N-acetylaspartylglutamate synthase
Reaction
ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetyl-L-aspartyl-L-glutamate
Other name(s)
N-acetylaspartylglutamate synthetase,
NAAG synthetase,
NAAGS,
RIMKLA (gene name) (ambiguous),
RIMKLB (gene name) (ambiguous)
Systematic name
N-acetyl-L-aspartate:L-glutamate ligase (ADP, N-acetyl-L-aspartyl-L-glutamate-forming)
Comment
The enzyme, found in animals, produces the neurotransmitter N-acetyl-L-aspartyl-L-glutamate. One isoform also has the activity of EC 6.3.1.17, β-citrylglutamate synthase [2], while another isoform has the activity of EC 6.3.2.42, N-acetylaspartylglutamylglutamate synthase [3].
History
created 2014
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.14.2 created 1972, deleted 1976 1.14.14.4 created 2000, deleted 2002
