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EC 1.1.1.398 Details
show Brenda entryEC number
1.1.1.398
Accepted name
2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase
Reaction
2-(glutathion-S-yl)-2-methylbut-3-en-1-ol + 2 NAD+ + H2O = 2-(glutathion-S-yl)-2-methylbut-3-enoate + 2 NADH + 2 H+ (overall reaction);;(1a) 2-(glutathion-S-yl)-2-methylbut-3-en-1-ol + NAD+ = 2-(glutathion-S-yl)-2-methylbut-3-enal + NADH + H+;;(1b) 2-(glutathion-S-yl)-2-methylbut-3-enal + NAD+ + H2O = 2-(glutathion-S-yl)-2-methylbut-3-enoate + NADH + H+
Other name(s)
isoH (gene name),
4-hydroxy-3-glutathionyl-3-methylbut-1-ene dehydrogenase
Systematic name
2-(glutathion-S-yl)-2-methylbut-3-en-1-ol:NAD+ oxidoreductase
Comment
The enzyme, characterized from the bacterium Rhodococcus sp. AD45, is involved in isoprene degradation.
History
created 2016
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.14.13.45 created 1992, deleted 2003
