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EC 1.14.12.13 Details
EC number
1.14.12.13
Accepted name
2-halobenzoate 1,2-dioxygenase
Reaction
a 2-halobenzoate + NADH + H+ + O2 = catechol + a halide anion + NAD+ + CO2
Other name(s)
2-chlorobenzoate 1,2-dioxygenase
Systematic name
2-halobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dehalogenating, decarboxylating)
CAS registry number
125268-83-9
Comment
A multicomponent enzyme system composed of a dioxygenase component and an electron transfer component. The latter contains FAD. The enzyme, characterized from the bacterium Burkholderia cepacia 2CBS, has a broad substrate specificity. Substrates include 2-fluorobenzoate, 2-chlorobenzoate, 2-bromobenzoate, and 2-iodobenzoate, which are processed in this order of preference.
History
created 1992, modified 2012
EC Tree
1.14.13.45 created 1992, deleted 2003