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EC 4.1.1.100 Details
EC number
4.1.1.100
Accepted name
prephenate decarboxylase
Reaction
prephenate = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2
Other name(s)
BacA, AerD, SalX, non-aromatizing prephenate decarboxylase
Systematic name
prephenate carboxy-lyase (3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate-forming)
Comment
The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. The enzyme isomerizes only the pro-R double bond in prephenate.
History
created 2015
EC Tree
1.3.99.9 created 1976, deleted 2002