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EC 4.6.1.16 Details
show Brenda entryEC number
4.6.1.16
Accepted name
tRNA-intron lyase
Reaction
pretRNA = a 3′-half-tRNA molecule with a 5′-OH end + a 5′-half-tRNA molecule with a 2′,3′-cyclic phosphate end + an intron with a 2′,3′-cyclic phosphate and a 5′-hydroxyl terminus
Other name(s)
transfer ribonucleate intron endoribonuclease,
tRNA splicing endonuclease,
splicing endonuclease,
tRNATRPintron endonuclease,
transfer splicing endonuclease
Systematic name
pretRNA lyase (intron-removing; cyclic-2′,3′-phosphate-forming)
CAS registry number
117444-13-0
Comment
The enzyme catalyses the final stage in the maturation of tRNA molecules.
History
created 1992 as EC 3.1.27.9, transferred 2014 to EC 4.6.1.16
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.13.11.21 created 1972, deleted 2001
