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EC 3.1.3.79 Details
EC number
3.1.3.79
Accepted name
mannosylfructose-phosphate phosphatase
Reaction
β-D-fructofuranosyl-α-D-mannopyranoside 6F-phosphate + H2O = β-D-fructofuranosyl-α-D-mannopyranoside + phosphate
Other name(s)
mannosylfructose-6-phosphate phosphatase, MFPP
Systematic name
β-D-fructofuranosyl-α-D-mannopyranoside-6F-phosphate phosphohydrolase
Comment
This enzyme, from the soil proteobacterium and plant pathogen Agrobacterium tumefaciens strain C58, requires Mg2+ for activity. Mannosylfructose is the major endogenous osmolyte produced by several α-proteobacteria in response to osmotic stress and is synthesized by the sequential action of EC 2.4.1.246 (mannosylfructose-phosphate synthase) followed by this enzyme. While mannosylfructose 6-phosphate is the physiological substrate, the enzyme can use sucrose 6-phosphate very efficiently. The F in mannosylfructose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
History
created 2009
EC Tree
1.5.3.3 created 1961, deleted 1972
1.5.3.8 created 1989, deleted 1992
1.5.3.9 created 1989, modified 1999, deleted 2002